"Jan. 14, 2014 — Treatment and "cure" of breast cancer doesn't ensure that the disease won't spread to the brain. Too often, sometimes years after an initial diagnosis and remission, breast cancer cells are discovered growing as new tumors within the brain. Now City of Hope researchers have found how this happens.Breast cancer cells masquerade as neurons, allowing them to hide from the immune system, cross the blood-brain barrier and begin to form ultimately-deadly brain tumors, the researchers found.
"The most dreaded location for cancer to spread is the brain," said Rahul Jandial, a City of Hope neurosurgeon who led the study, available online and slated for print publication in theProceedings of the National Academy of Sciences in February. "As we have become better at keeping cancer at bay with drugs such as Herceptin, women are fortunately living longer. In this hard-fought life extension, brain metastastes are being unmasked as the next battleground for extending the lives of women with breast cancer."
Via Susan Zager