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Rescooped by lane suchy from Amazing Science!

Can You Mix Those Two Drugs? Ask Dr. Google

Can You Mix Those Two Drugs? Ask Dr. Google | The Amazing Topic that will definatly get you more scoopit followers and views get ready for this boyz |

Analyzing queries made to Google, Bing, and other search engines can reveal the potentially dangerous consequences of mixing prescriptions before they are known to the Food and Drug Administration (FDA), according to a new study. Such data mining could even expose medical risks that slip through clinical trials undetected.


Pharmaceuticals often have side effects that go unnoticed until they're already available to the public. This is especially true of side effects that emerge when two drugs interact, largely because drug trials try to pinpoint the effects of one drug at a time. Physicians have a few ways to hunt for these hidden risks, such as reports to FDA from doctors, nurses, and patients. One study, in 2011, data-mined those FDA reports and uncovered a hidden drug interaction: When taken together, the antidepressant paroxetine and the cholesterol suppressant pravastatin cause hyperglycemia, or high blood sugar. After verifying that finding with experiments, the researchers behind the study wondered what other information sources were left untapped.


Enter search engines. Much like Google Flu Trends reveals influenza outbreaks by tracking flu-related search terms, search queries about drug combinations and possible side effects—say, "paroxetine," "pravastatin," and "hyperglycemia"—might enable researchers to identify unanticipated downsides to medications, says bioinformatics researcher Nigam Shah of Stanford University in Palo Alto, California. "If a lot of people are concerned about a symptom, that in itself is valuable information."


Although many bad reactions to drugs never get reported to doctors, people talk about what's bothering them all the time on a casual basis to their friends or online, notes computational biologist Nicholas Tatonetti of Columbia University, who was also involved with the study. "They don't really know," he says. "They're just reporting on their symptoms, which is just a normal thing that humans love to do."


Before anyone knew about the drug combination's side effects, one out of 10 people searching for both drugs also looked for terms related to hyperglycemia—about twice as often as did people looking up paroxetine or pravastatin alone. The researchers then looked for 62 other drug pairings, half known to cause hyperglycemia and the other half known not to. They found that the data-mining procedure correctly predicted whether the drug combo did or did not cause hyperglycemia about 81% of the time.


The findings add yet another resource for scientists to find clues to drug risks, Shah says, and this one can be monitored in real time. One hope, he notes, is that search engine companies could analyze the data and ship the results to FDA, which would then screen the information and alert doctors of new potential risks. "This is information, we have access to it. As a society we're sitting on it," he says. "We could use it to assist the FDA, which currently relies on the reported sources."


The new study is "exciting" because the field is so new, says biomedical informatics researcher Hojjat Salmasian of Columbia University, who was not involved with the work. "We don't know how much potential it has," he says. "But based on the results that have been published so far in this study and other similar studies, it seems like this is a very important field to explore."

Via Dr. Stefan Gruenwald
lane suchy's insight:

California Love"
(feat. Dr. Dre)

California love!

California... knows how to party
California... knows how to party
In the citaaay of L.A.
In the citaaay of good ol' Watts
In the citaaay, the city of Compton
We keep it rockin! We keep it rockin!

[Verse 1: Dr. Dre]
Now let me welcome everybody to the wild, wild west
A state that's untouchable like Elliot Ness
The track hits ya eardrum like a slug to ya chest
Pack a vest for your Jimmy in the city of sex
We in that sunshine state where that bomb ass hemp be
The state where ya never find a dance floor empty
And pimps be on a mission for them greens
Lean mean money-makin-machines servin fiends
I been in the game for ten years makin rap tunes
Ever since honeys was wearin sassoon
Now it's '95 and they clock me and watch me
Diamonds shinin lookin like I robbed Liberace
It's all good, from Diego to tha Bay
Your city is tha bomb if your city makin pay
Throw up a finger if ya feel the same way
Dre puttin it down for


Shake it shake it baby
Shake it shake it baby
Shake it shake it mama
Shake it Cali
Shake it shake it baby
Shake it shake it shake it shake it...

[Verse 2: 2Pac]
Out on bail fresh outta jail, California dreamin
Soon as I stepped on the scene, I'm hearin hoochies screamin
Fiendin for money and alcohol
The life of a west side playa where cowards die and it's all ball
Only in Cali where we riot not rally to live and die
In L.A. we wearin Chucks not Ballies (that's right)
Dressed in Locs and khaki suits and ride is what we do
Flossin but have caution we collide with other crews
Famous cause we program worldwide
Let'em recognize from Long Beach to Rosecrans
Bumpin and grindin like a slow jam, it's west side
So you know the row won't bow down to no man
Say what you say
But give me that bomb beat from Dre
Let me serenade the streets of L.A.
From Oakland to Sacktown
The Bay Area and back down
Cali is where they put they mack down
Give me love!


[Dre:] Now make it shake...


[Outro: Dre, 2Pac]
Uh, yeah, uh, longbeach in tha house, uh yeah
Oaktown, Oakland definately in tha house hahaha
Frisko, Frisko
[Tupac:] Hey, you know LA is up in this
Pasadena, where you at
Yeah, Inglewood, Inglewood always up to no good
[Tupac:] Even Hollywood tryin to get a piece baby
Sacramento, sacramento where ya at? yeah

Throw it up y'all, throw it up, Throw it up
Let's show these fools how we do this on that west side
Cause you and I know it's tha best side

Yeah, That's riight
West coast, west coast
Uh, California Love
California Love
Reece Bobby's comment, March 8, 2013 10:14 AM
You're speaking directly to my soul.. how do you do it?
lane suchy's comment, March 8, 2013 3:47 PM
Three words Dalhi Lama
Rescooped by lane suchy from Machinimania!

Reese Bobby invents lightsabers!!!!!!

Reese Bobby invents lightsabers!!!!!! | The Amazing Topic that will definatly get you more scoopit followers and views get ready for this boyz |
knights of the old republic Star Wars / Lucasfilm rumors have been running rampant in the… 4 months since Disney acquired the company (and it's a testament to just how much movement there's been that the interval since ...

Via Henrik Safegaard - Cloneartist
lane suchy's insight:

wooooooow da da daaaa

Reece Bobby's comment, February 28, 2013 4:03 PM
Holy Crow, it really does!
BCHS-RileyMartin's comment, March 6, 2013 2:06 PM
thanks for the 200 followers :)
lane suchy's comment, March 6, 2013 4:33 PM
your welcome tucker town :D