TECHNOLOGY=SCIENC...
Follow
Find
55 views | +0 today
 
Rescooped by Harpal S.sandhu from Social Foraging
onto TECHNOLOGY=SCIENCE=CREATIVITY
Scoop.it!

Protein Complex Formation: Computational Clarification of the Sequential versus Probabilistic Recruitment Puzzle

Protein Complex Formation: Computational Clarification of the Sequential versus Probabilistic Recruitment Puzzle | TECHNOLOGY=SCIENCE=CREATIVITY | Scoop.it

Our current view on how protein complexes assemble and disassemble at promoter sites is based on experimental data. For instance this data is provided by biochemical methods (e.g. ChIP-on-chip assays) or GFP-based assays. These two approaches suggest very different characteristics for protein recruitment processes that regulate and initiate gene transcription. Biochemical methods suggest a strictly ordered and consecutive protein recruitment while GFP-based assays draw a picture much closer to chaotic or stochastic recruitment. To understand the reason for these conflicting results, we design a generalized recruitment model (GRM) that allows to simulate all possible scenarios between strictly sequential recruitment and completely probabilistic recruitment. With this model we show that probabilistic, transient binding events that are visible in GFP experiments can not be detected by ChIP experiments. We demonstrate that sequential recruitment processes and probabilistic recruitment processes that contain “shortcuts” exhibit periodic dynamics and are hard to distinguish with standard ChIP measurements. Therefore we propose a simple experimental method that can be used to discriminate sequential from probabilistic recruitment processes. We discuss the limitations of this method.


Via Ashish Umre
more...
No comment yet.
Your new post is loading...
Your new post is loading...
Scooped by Harpal S.sandhu
Scoop.it!

Michael Woodside Nanotechnology Part 1 Fall 2013 Technology and Future of Medicine Course

Dr. Michael Woodside presents the Promise and Perils of Nanotechnology Part 1 on October 8, 2013 in the Technology and Future of Medicine course LABMP 590 at...
more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Fuel gain over unity in an inertially confined fusion implosion

Boot-strapping results when alpha particles, helium nuclei produced in the deuterium-tritium (DT) fusion process, deposit their energy in the DT fuel, rather than escaping. ...
more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

3D Virtual Worlds in Health Care | franzcalvo

3D Virtual Worlds in Health Care | franzcalvo | TECHNOLOGY=SCIENCE=CREATIVITY | Scoop.it
Background: A three-dimensional virtual world (3DVW) is a computer-simulated electronic 3D virtual environment that users can explore, inhabit, communicate, and interact with via avatars, which are graphical representations ...
more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Intelligent Alien Life Could Be Found by 2040 - Next Big Future

science (3154) energy (2895) technology (2035) space (1786) united states (1748) nuclear (1707) china (1668) world (1657) medicine (1290) materials (1004) military (523) environment (516) robotics (506) solar (493) cars (477) fusion (400) ....
more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Dwave Doubling quantum qubits each year and planning to double ...

D-Wave last year introduced the second-generation quantum computer called D-Wave Two which has a “list price north of $10 million,” according a research note from financial firm Sterne Agee on Wednesday.
more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Math modeling integral to synthetic biology research - Phys.org

Math modeling integral to synthetic biology research - Phys.org | TECHNOLOGY=SCIENCE=CREATIVITY | Scoop.it
A long-standing challenge in synthetic biology has been to create gene circuits that behave in predictable and robust ways. Mathematical modeling experts from the ... Energy breakthrough uses sun to create solar energy materials.
more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Big Data, Synthetic Biology And Space Planes Are The Weapons Of ...

Big Data, Synthetic Biology And Space Planes Are The Weapons Of ... | TECHNOLOGY=SCIENCE=CREATIVITY | Scoop.it
According to the Defense Advanced Research Projects Agency, it's big data, synthetic biology and space planes. “We can see the information revolution unfolding across ... It saw its spending increased to triple inFY2015 to $15 million.
more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Michio Kaku: This is Your Brain on a Laser Beam

Don't miss new Big Think videos! Subscribe by clicking here: http://goo.gl/CPTsV5 Dr. Michio Kaku returns to Big Think studios to discuss his latest book, Th...
more...
No comment yet.
Rescooped by Harpal S.sandhu from MATHEMATICS-NETWORK=NATURE=BASICS
Scoop.it!

Generating 3D Topologies with Multiple Constraints on the GPU | hgpu.org

Generating 3D Topologies with Multiple Constraints on the GPU | Computer science, CUDA, nVidia, nVidia GeForce GTX 480, Topology optimization problem


Via Mikael Bourges-Sevenier, Harpal S.sandhu
more...
Rescooped by Harpal S.sandhu from MATHEMATICS-NETWORK=NATURE=BASICS
Scoop.it!

How Signals, Geometry, and Topology are Influencing Data Science

I've been noticing unlikely areas of mathematics pop-up in data analysis. While signal processing is a natural fit, topology, differential and algebraic geometry aren't exactly areas you associate with...

Via Ed Stenson, Pierre Levy, Harpal S.sandhu
more...
Harpal S.sandhu's curator insight, July 9, 2013 3:11 PM

geometry

Harpal S.sandhu's curator insight, July 9, 2013 3:20 PM

data science

Harpal S.sandhu's curator insight, July 15, 2013 2:25 PM

DATA SCIENCE

Rescooped by Harpal S.sandhu from MATHEMATICS-NETWORK=NATURE=BASICS
Scoop.it!

Videos 3-4

Videos 3-4 | TECHNOLOGY=SCIENCE=CREATIVITY | Scoop.it
more...
No comment yet.
Rescooped by Harpal S.sandhu from CxConferences
Scoop.it!

Collective Intelligence 2014

This interdisciplinary conference seeks to bring together researchers from a variety of fields relevant to understanding and designing collective intelligence of many types.
Topics of interest include but are not limited to:
• human computation
• social computing
• crowdsourcing
• wisdom of crowds (e.g., prediction markets)
• group memory and extended cognition
• collective decision making and problem-solving
• participatory and deliberative democracy
• animal collective behavior
• organizational design
• public policy design (e.g., regulatory reform)
• ethics of collective intelligence (e.g., “digital sweatshops”)
• computational models of group search and optimization
• emergence and evolution of intelligence
• new technologies for making groups smarter

 

http://collective.mech.northwestern.edu


Via Complexity Digest
Harpal S.sandhu's insight:

COLLECTIVE INTELLIGENCE

more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Data driven eugenics, Genetic Enhancement, computer cloud AI via ...

However, highly user friendly voice and very precise (Leap Motion) gesture control and Google Glass augmented reality displays could provide a sufficiently seamless two-way connection to our gadgets and computers.
Harpal S.sandhu's insight:

hologrphic world .multi universe

more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Materials database proves its mettle with new discoveries - Phys.org

Materials database proves its mettle with new discoveries - Phys.org | TECHNOLOGY=SCIENCE=CREATIVITY | Scoop.it
No lithium-containing materials with the CO3 and PO4 chemical groups found in these compounds exist in nature — these materials are fully synthetic and unexpected. ...
more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Stronger benchmarks needed to fully quantify quantum speedup ...

Stronger benchmarks needed to fully quantify quantum speedup ... | TECHNOLOGY=SCIENCE=CREATIVITY | Scoop.it
(Phys.org) —Texas A&M University physicist Helmut G. Katzgraber's research takes him to the crossroads of physics, computer science, quantum information theory and statistical mechanics. ...
more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Halfway from 1990 to 2038 - Next Big Future

There will be two to six major approaches to quantum computing nearing the million qubit scale. ... Terrestrial energy will have made several dozen molten salt reactors for steam extraction of oil from Canada's oilsands.
more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Distinguishing Classical and Quantum Models for the D-Wave Device

We study the population ratio of the isolated and clustered states as a function of the overall energy scale of the Ising term, and the distance between the final state and the Gibbs state, and find that these are sensitive probes that distinguish...
more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Groundbreaking optical device could enhance optical information ...

Groundbreaking optical device could enhance optical information ... | TECHNOLOGY=SCIENCE=CREATIVITY | Scoop.it
Researchers at Washington University in St. Louis have used the same phenomenon to build an optical device that may lead to new and more powerful computers that run faster and cooler. Lan Yang ...
more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Synthetic biologists break new ground in medicine, energy - Phys.org

Synthetic biologists break new ground in medicine, energy - Phys.org | TECHNOLOGY=SCIENCE=CREATIVITY | Scoop.it
The hot field of synthetic biology uses tools and concepts from physics, engineering and computer science to build new biological systems. Newly understood genomic sequencing and advances in molecular biology, as well ...
more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Future computer memory - Memristors, cheaper MRAM, and Phase ...

451 Research provides computer memory analysis at computerweekly. ... Labels: computer memory, computers, future, HP, memristors, mram, phase change material, science, technology ...
more...
No comment yet.
Scooped by Harpal S.sandhu
Scoop.it!

Timothytrespas- Still beating myself up over not doing more for others...

Timothytrespas: Still Beating myself up over not doing more for others... How targeting has made me selfish and horrible! Or not. I am clearly conflicted ins...
more...
No comment yet.
Rescooped by Harpal S.sandhu from MATHEMATICS-NETWORK=NATURE=BASICS
Scoop.it!

Math Videos, Games, and Worksheets for the Common Core | Math Chimp

Math Videos, Games, and Worksheets for the Common Core | Math Chimp | TECHNOLOGY=SCIENCE=CREATIVITY | Scoop.it
Check out our selection of free math videos, games, and worksheets. We collect the best math activities online for K-8 and organize them by the Common Core Standards.
more...
No comment yet.
Rescooped by Harpal S.sandhu from MATHEMATICS-NETWORK=NATURE=BASICS
Scoop.it!

Plane Math

Click here to edit the title

more...
No comment yet.
Rescooped by Harpal S.sandhu from MATHEMATICS-NETWORK=NATURE=BASICS
Scoop.it!

Math Interactives

more...
Ayad Altory's curator insight, February 10, 2013 6:57 AM

משחקים במתמטיקה

Rescooped by Harpal S.sandhu from The 21st Century
Scoop.it!

Major Players in the MOOC Universe - The Digital Campus 2013 - The Chronicle of Higher Education

Major Players in the MOOC Universe - The Digital Campus 2013 - The Chronicle of Higher Education | TECHNOLOGY=SCIENCE=CREATIVITY | Scoop.it
Explore connections among the major players.

Via Susan Bainbridge
Harpal S.sandhu's insight:

GREAT DIGITAL DELIVERY

 

more...
academiPad's curator insight, May 2, 2013 7:10 AM

A brief intro into the MOOC universe: Who backs what?

davidgibson's curator insight, May 2, 2013 1:44 PM

Remarkable how this subsector has taken off! Does anyone have a link to a critique and categorization?

Craig Fleming's curator insight, May 19, 2013 9:10 PM

Loving the disruption. Higher Ed is starting to quaver.