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Efficient TALEN construction and evaluation methods for human cell and animal applications - Sakuma - 2013 - Genes to Cells - Wiley Online Library

Efficient TALEN construction and evaluation methods for human cell and animal applications - Sakuma - 2013 - Genes to Cells - Wiley Online Library | TALENS | Scoop.it
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PLOS Computational Biology: Computational Predictions Provide Insights into the Biology of TAL Effector Target Sites

PLOS Computational Biology: Computational Predictions Provide Insights into the Biology of TAL Effector Target Sites | TALENS | Scoop.it
PLOS Computational Biology is an open-access
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BMC Bioinformatics | Full text | Mojo Hand, a TALEN design tool for genome editing applications

Recent studies of transcription activator-like (TAL) effector domains fused to nucleases (TALENs) demonstrate enormous potential for genome editing.
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Efficient Targeted Mutagenesis in Medaka Using Custom-Designed Transcription Activator-Like Effector Nucleases

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Cold Spring Harbor Symposium on Quantitative Biology: Effector Biology of Plant-Associated Organisms: Concepts and Perspectives (2012)

Cold Spring Harbor Symposium on Quantitative Biology: Effector Biology of Plant-Associated Organisms: Concepts and Perspectives (2012) | TALENS | Scoop.it

Every plant is closely associated with a variety of living organisms. Therefore, deciphering howplants interact with mutualistic and parasitic organisms is essential for a comprehensive understanding of the biology of plants. The field of plant–biotic interactions has recently coalesced around an integrated model. Major classes of molecular players both from plants and their associated organisms have been revealed. These include cell surface and intracellular immune receptors of plants, as well as apoplastic and host-cell translocated (cytoplasmic) effectors of the invading organism. This article focuses on effectors, molecules secreted by plant-associated organisms that alter plant processes. Effectors have emerged as a central class of molecules in our integrated view of plant–microbe interactions. Their study has significantly contributed to advancing our knowledge of plant hormones, plant development, plant receptors, and epigenetics. Many pathogen effectors are extraordinary examples of biological innovation; they include some of themost remarkable proteins knownto function inside plant cells. Here, we review some of the key concepts that have emerged from the study of the effectors of plant-associated organisms. In particular, we focus on how effectors function in plant tissues and discuss future perspectives in the field of effector biology.

 

http://kamounlab.dreamhosters.com/pdfs/CSHSQB_2012.pdf


Via Kamoun Lab @ TSL, Freddy Monteiro
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