If you want to learn how something works, one strategy is to take it apart and put it back together again. For 10 years, a global initiative called the Blue Brain Project--hosted at the Ecole Polytechnique Federale de Lausanne (EPFL)--has been attempting to do this digitally with a section of juvenile rat brain. The project presents a first draft of this reconstruction, which contains over 31,000 neurons, 55 layers of cells, and 207 different neuron subtypes, on October 8 in Cell.
Heroic efforts are currently being made to define all the different types of neurons in the brain, to measure their electrical firing properties, and to map out the circuits that connect them to one another. These painstaking efforts are giving us a glimpse into the building blocks and logic of brain wiring. However, getting a full, high-resolution picture of all the features and activity of the neurons within a brain region and the circuit-level behaviors of these neurons is a major challenge.
Henry Markram and colleagues have taken an engineering approach to this question by digitally reconstructing a slice of the neocortex, an area of the brain that has benefitted from extensive characterization. Using this wealth of data, they built a virtual brain slice representing the different neuron types present in this region and the key features controlling their firing and, most notably, modeling their connectivity, including nearly 40 million synapses and 2,000 connections between each brain cell type.
"The reconstruction required an enormous number of experiments," says Markram, of the EPFL. "It paves the way for predicting the location, numbers, and even the amount of ion currents flowing through all 40 million synapses."
Once the reconstruction was complete, the investigators used powerful supercomputers to simulate the behavior of neurons under different conditions. Remarkably, the researchers found that, by slightly adjusting just one parameter, the level of calcium ions, they could produce broader patterns of circuit-level activity that could not be predicted based on features of the individual neurons. For instance, slow synchronous waves of neuronal activity, which have been observed in the brain during sleep, were triggered in their simulations, suggesting that neural circuits may be able to switch into different "states" that could underlie important behaviors.
We’ve all heard of Schrödinger’s cat, a famous thought experiment where a cat is simultaneously alive and dead. In a new study, physicists hope to take this one step further by putting a microbe in two places at once.
Summary - Analysis conclusively shows over 1.25 million new jobs created during the last 6 years at companies making extensive use of robots. The detailed Robotenomics research report outlines full interviews and analysis of the key findings. Ever since “the great recession” began in the latter part of 2008 it has been widely speculated that the…
sing images from the NASA/ESA Hubble Space Telescope and ESO's Very Large Telescope, astronomers have discovered never-before-seen structures within a dusty disc surrounding a nearby star. The fast-moving wave-like features in the disc of the star AU Microscopii are unlike anything ever observed, or even predicted, before now. The origin and nature of these features present a new mystery for astronomers to explore. The results are published in the journal Nature on 8 October 2015.
AU Microscopii, or AU Mic for short, is a young, nearby star surrounded by a large disc of dust . Studies of such debris discs can provide valuable clues about how planets, which form from these discs, are created.
Astronomers have been searching AU Mic's disc for any signs of clumpy or warped features, as such signs might give away the location of possible planets. And in 2014 they used the powerful high-contrast imaging capabilities of ESO's newly installed SPHERE instrument, mounted on the Very Large Telescope for their search -- and discovered something very unusual.
"Our observations have shown something unexpected," explains Anthony Boccaletti of the Observatoire de Paris, France, lead author on the paper. "The images from SPHERE show a set of unexplained features in the disc which have an arch-like, or wave-like, structure, unlike anything that has ever been observed before."
Five wave-like arches at different distances from the star show up in the new images, reminiscent of ripples in water. After spotting the features in the SPHERE data the team turned to earlier images of the disc taken by the NASA/ESA Hubble Space Telescope in 2010 and 2011 to see whether the features were also visible in these . They were not only able to identify the features on the earlier Hubble images -- but they also discovered that they had changed over time. It turns out that these ripples are moving -- and very fast!
"We reprocessed images from the Hubble data and ended up with enough information to track the movement of these strange features over a four-year period," explains team member Christian Thalmann (ETH Zürich, Switzerland). "By doing this, we found that the arches are racing away from the star at speeds of up to about 40,000 kilometers/hour!"
Gill Pratt, one of the top roboticists in the world, says people should not fear robots because they have legs. He says you should be more worried about all the data you carry around on your cellphone, and who has access to it.
Sharing your scoops to your social media accounts is a must to distribute your curated content. Not only will it drive traffic and leads through your content, but it will help show your expertise with your followers.
How to integrate my topics' content to my website?
Integrating your curated content to your website or blog will allow you to increase your website visitors’ engagement, boost SEO and acquire new visitors. By redirecting your social media traffic to your website, Scoop.it will also help you generate more qualified traffic and leads from your curation work.
Distributing your curated content through a newsletter is a great way to nurture and engage your email subscribers will developing your traffic and visibility.
Creating engaging newsletters with your curated content is really easy.