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Engineering Biology: Mads Kaern at TEDxUOttawa

Synthetic Biology is a leading-edge science and engineering discipline and will be one of the dominant industries of the 21st century. Based on advancements in DNA synthesis and manipulation technologies, Synthetic Biology is an evolution of genetic engineering towards the creation of new, artificial lifeforms that can be used to manufacture new materials, biofuels, medicines, vaccines, and many additional industrial and consumer products. Because Synthetic Biology at its core relies on extensive manipulation of DNA material, or even the use of entirely man-made genomes, the advancement of the field has ignited a fierce debate about whether its tremendous potential benefits can be realized in a safe and ethical manner.

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Synthetic Biology
All about the growing field of synthetic biology
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Rewriting the Genome Using CRISPR and Synthetic Biology

The CRISPR/Cas9 system has emerged as one of the leading tools for modifying genomes of organisms ranging from E. coli to humans. Additionally, the simple gene targeting mechanism of CRISPR technology has been modified and adapted to other applications that include gene regulation, detection of intercellular trafficking, and pathogen detection. With a wealth of methods for introducing Cas9 and gRNAs into cells, it can be challenging to decide where to start. In this presentation, Dr Adam Clore describes the CRISPR mechanism and some of the most prominent uses for CRISPR, along with methods where IDT technologies can assist scientists in designing, testing, and executing a variety of CRISPR-mediated experiments.

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Synthetic biology: How to peel fruits’ chemicals

Synthetic biology: How to peel fruits’ chemicals | Synthetic Biology | Scoop.it

New method of producing nootkatone offers the best combination of affordability and sustainability

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Design and build of synthetic DNA goes back to 'BASIC'

Design and build of synthetic DNA goes back to 'BASIC' | Synthetic Biology | Scoop.it

A new technique for creating artificial DNA that is faster, more accurate and more flexible than existing methods has been developed by scientists.

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Changing the World with Color Changing Flowers

Changing the World with Color Changing Flowers | Synthetic Biology | Scoop.it

Keira Havens is the co-founder of Revolution Bioengineering, and this week the company launched a crowd funding campaign to produce flowers that can change colors.


And what is the revolution?


“We want to change the world,” says Keira. “We really want to make a difference in the way people think about biotechnology. For a long time it’s been the realm of large companies and behind-the-scenes labs, and we want to make it a part of folks' everyday lives.”


Keira hopes that a genetically engineered plant product which is not eaten or produced by a big company will not be as threatening to those afraid of GMOs and might possible affect the ongoing debate over genetically modified products.


The flower will not be available until 2017. So it will be some time before Keira and her team are turning a pumpkin into a stagecoach.

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Richard Spencer's curator insight, March 6, 1:37 PM

Wow  this  will be  fascinating  it is  known  that  our  common  Hydranga  changes  colour  with  the  different  PH  levels  but  now  we  can  have  biogentic  plants  thats  does  that  too 

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Review of RevBio’s Crowd Funding Campaign

Review of RevBio’s Crowd Funding Campaign | Synthetic Biology | Scoop.it

Art’s primary function is to cause people to re-evaluate their environment. A synthetic biology artists’ responsibility is to communicate to the public what the field of synthetic biology is capable of and evaluate how it affects their lives. At SynBioBeta San Francisco’s 2014 Conference, Revolution Biology (RevBio) Founder and CEO, Kiera Havens, announced her company would have a crowdfunding campaign in early 2015 for a synthetic biology art project.

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Nanocrafter: Playing a Game of Synthetic Biology

Nanocrafter: Playing a Game of Synthetic Biology | Synthetic Biology | Scoop.it

It looks like just another science puzzle. In reality, it is part of a broader goal to enable non-scientists to contribute to synthetic biology research.

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Would You Like to Grow Color-Changing Flowers?

Would You Like to Grow Color-Changing Flowers? | Synthetic Biology | Scoop.it

A Colorado company is working to genetically engineer petunias that change colors throughout the day

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Scientists Reprogram Plants for Drought Tolerance

Scientists Reprogram Plants for Drought Tolerance | Synthetic Biology | Scoop.it

UC Riverside-led research in synthetic biology provides a strategy that has reprogrammed plants to consume less water after they are exposed to an agrochemical, opening new doors for crop improvement

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Synthetic Genomics: Redesign and synthesis of the first multicellular eukaryotic genome

Synthetic Genomics: Redesign and synthesis of the first multicellular eukaryotic genome | Synthetic Biology | Scoop.it

The field of synthetic biology, designing and building engineered biological systems through DNA synthesis and genetic engineering, is rapidly moving to a genome scale. In a similar trajectory to genomic sequencing and genome projects two decades ago, it has moved from engineering single genes, entire synthetic bacterial genomes (J Craig Venter’s notorious“Synthia”), to the eukaryotic organism stage. The “Sc2.0” synthetic yeast genome project, is aninternational consortium synthesizing “designer eukaryotic genomes“ for all of the 16 chromosomes (and roughly 14Mb of sequence) of Baker’s yeast Saccharomyces cerevisiae. With the first chromosome published last year in Science, and many more already completed, and planning for the next step up is already being discussed. Being heavily involved in Sc2.0, and already producing several chromosomes (pictured), our colleagues at BGI organized a workshop covering this very topic at the end of last year. Chantal Shen and Huanming Yang from BGI and Patrick Cai from Edinburgh have written us a guest posting on the discussions that went on at the workshop, and what the proposed next steps are for organismal scale synthetic genomics.

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No Escape

No Escape | Synthetic Biology | Scoop.it

Biological safety lock for genetically modified organisms

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Can yeast and synthetic techniques solve a 10-year-old biological puzzle?

Can yeast and synthetic techniques solve a 10-year-old biological puzzle? | Synthetic Biology | Scoop.it

A Concordia grad student is using innovative science to investigate a key cellular process.

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The Quest To Reproduce The Scent Of A Rose, With Designer Microbes

The Quest To Reproduce The Scent Of A Rose, With Designer Microbes | Synthetic Biology | Scoop.it

Stop and smell the genetically engineered yeast.

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Can Life Be Mimicked in Silicon?

Can Life Be Mimicked in Silicon? | Synthetic Biology | Scoop.it

In a step toward sophisticated artificial cells, scientists have engineered a silicon chip that can produce proteins from DNA, the most basic function of life.

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Bacteria Could Help Clean Up Radioactive Soil

Bacteria Could Help Clean Up Radioactive Soil | Synthetic Biology | Scoop.it

A highly acidic protein from salt-loving bacteria could be used to remove radioactive cesium from contaminated soil. 

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The DIY biohacking revolution is here

The DIY biohacking revolution is here | Synthetic Biology | Scoop.it

Just as big tech companies like Google found their start in garages, the future of biology will be built in garages and kitchens, too.

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Would you wear yeast perfume? Microbes used to brew scent

Would you wear yeast perfume? Microbes used to brew scent | Synthetic Biology | Scoop.it

Genetically engineered microorganisms could replace flowers as sources of ingredients for perfumes - and even recreate scents from plants long extinct

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Color-Changing Flowers—Biotechnology for Everyone

Color-Changing Flowers—Biotechnology for Everyone | Synthetic Biology | Scoop.it

A start-up synthetic biology company is bioengineering color-changing flowers to capture the imagination of the general public and make genetically modified organisms (GMOs) more accessible, personal, and ultimately, better understood.

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Lessane K.'s curator insight, March 9, 1:00 PM

I chose this article because my senior project requires me to spend time researching career opportunities in different engineering fields. This start-up is planning on making a profit through the engineering of flowers that can change color. I have mixed feelings about these and other GMO's in general. I believe in consumer rights, and so the concealment of the information that a certain organism is genetically modified is to me a great breach of ethics. Here, most people would realize that the flowers are genetically modified. As far as the health risks involved, I doubt that these flowers cause any harm to humans or animals (since the scientists are just using chemicals naturally present in the flowers), so the company is going to do well, I think. My deepest reservations about this issue go back to something more fundamental than GMO's--the nature of beauty (or rather, the beauty of nature). Though good and beautiful, art is art, and will never be equal to nature. The process which created the object is just as important as the object itself (why else do we say "hand-crafted" is better than "factory-made"). For this reason, I think the work of these bioengineers should be admired, but we should always be wary that what we do cannot always compare to what is in nature already. Instead, we should learn to use nature while altering it as little as possible. Because of my views on this kind of engineering, I think it would be better for me to avoid bioengineering and to look further into electrical or mechanical engineering.

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Synthetic biology breakthrough leads to cheaper statin production

Synthetic biology breakthrough leads to cheaper statin production | Synthetic Biology | Scoop.it

University of Manchester researchers, together with industrial partner DSM, have developed a single-step fermentative method for the production of leading cholesterol-lowering drug, pravastatin, which will facilitate industrial-scale statin drug production.

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Team Creates New Approach to Gene Therapy

Team Creates New Approach to Gene Therapy | Synthetic Biology | Scoop.it
Bioengineers at The University of Texas at Dallas have created a novel gene-delivery system that shuttles a gene into a cell, but only for a temporary stay, providing a potential new gene-therapy strategy for treating disease.
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Business Secretary announces £40M for UK synthetic biology

Business Secretary announces £40M for UK synthetic biology | Synthetic Biology | Scoop.it

Business Secretary Vince Cable has announced £40M investment in UK synthetic biology at the Manchester Institute for Biotechnology, where researchers are using the technology to investigate how to use bacteria in place of fossil fuels to produce the chemicals we need to manufacture a wide variety of everyday products from credit cards, to nappies, to Tupperware tubs.

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Rewriting the Genome Using CRISPR and Synthetic Biology

The CRISPR/Cas9 system has emerged as one of the leading tools for modifying genomes of organisms ranging from E. coli to humans. Additionally, the simple gene targeting mechanism of CRISPR technology has been modified and adapted to other applications that include gene regulation, detection of intercellular trafficking, and pathogen detection. With a wealth of methods for introducing Cas9 and gRNAs into cells, it can be challenging to decide where to start. In this presentation, Dr Adam Clore describes the CRISPR mechanism and some of the most prominent uses for CRISPR, along with methods where IDT technologies can assist scientists in designing, testing, and executing a variety of CRISPR-mediated experiments. For more informaton, visit: http://www.idtdna.com/crispr

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Rewriting the Genome Using CRISPR and Synthetic Biology

Rewriting the Genome Using CRISPR and Synthetic Biology | Synthetic Biology | Scoop.it

The CRISPR/Cas9 system has emerged as one of the leading tools for modifying genomes of organisms ranging from E. coli to humans. Additionally, the simple gene targeting mechanism of CRISPR technology has been modified and adapted to other applications that include gene regulation, detection of intercellular trafficking, and pathogen detection. With a wealth of methods for introducing Cas9 and gRNAs into cells, it can be challenging to decide where to start. This webinar will describe the CRISPR mechanism and some of the most prominent uses for CRISPR, along with methods where IDT technologies can assist scientists in designing, testing, and executing a variety of CRISPR-mediated experiments.

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