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Venter Supports DNA Printers

Venter Supports DNA Printers | Synthetic Biology | Scoop.it

The famed geneticist says his team is testing 3-D DNA printers that could churn out vaccines at home.

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Synthetic Biology
All about the growing field of synthetic biology
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iGEM Students Engineer Biological Tools for a Better World

iGEM Students Engineer Biological Tools for a Better World | Synthetic Biology | Scoop.it

The International Genetically Engineered Machine competition (iGEM) is the preeminent, multinational, undergraduate synthetic biology competition that takes place each year. The competition focuses on engineering aspects of synthetic biology as a foundation to develop research skills and foster collaboration among student participants. The duration of the competition is fairly short, with most of the work occurring over the summer months, when most students take time off from their studies. It is truly impressive the types of relevant world issues for which the teams are able to address and test solution in such a short time.

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Can Life Be Mimicked in Silicon?

Can Life Be Mimicked in Silicon? | Synthetic Biology | Scoop.it

In a step toward sophisticated artificial cells, scientists have engineered a silicon chip that can produce proteins from DNA, the most basic function of life.

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Who Made That Flavor? Maybe A Genetically Altered Microbe

Who Made That Flavor? Maybe A Genetically Altered Microbe | Synthetic Biology | Scoop.it

For practically our whole history of cooking and eating, we've gotten our spices and most flavors (not to mention all of the other basic nutrients that keep us alive) straight from plants.

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Can Synthetic Biology Sidestep the G.M.O. Backlash?

Can Synthetic Biology Sidestep the G.M.O. Backlash? | Synthetic Biology | Scoop.it

On a cold weekend last month, more than two thousand undergraduate scientists took over two levels of Boston’s Hynes Convention Center. Some wore full-body banana costumes, many wore coördinated team sweatshirts, and all appeared sleep-deprived. A handful of professors, one of whom was dressed as a stuffed olive, wandered among the students, and members of the F.B.I.’s Biological Countermeasures Unit handed out “BACTERIA OF INTEREST” trading cards—the microbial equivalent of the deck that the Pentagon created, in 2003, of Saddam Hussein and his loyalists.

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Evolution of catalysis: alternatives to nature’s molecules

Evolution of catalysis: alternatives to nature’s molecules | Synthetic Biology | Scoop.it

Life on Earth depends on catalysis. Chemical transformations essential for cellular function are too sluggish to happen spontaneously at ambient temperatures and pressures, thus nature has developed myriad catalysts (enzymes) that accelerate the many key reactions necessary for life. Today, proteins are largely responsible for this role, although nucleic acids (RNA and DNA), in addition to their familiar role in storage and propagation of genetic information, can also form enzymes: the ribosome, the molecular machine that manufactures proteins within all cells is an RNA enzyme. Indeed, life is widely thought to have begun with the emergence of a self-copying RNA catalyst; the origin of life itself depends on the emergence and evolution of catalysis.

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Self-destructing bio-drones could be the next Mars explorers

Self-destructing bio-drones could be the next Mars explorers | Synthetic Biology | Scoop.it

A group of students from Brown and Stanford University are collaborating with scientists from NASA’s Ames Research Centre on a biological drone, which they hope, one day, to send to Mars

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From five-cent synthesis to Martian DNA: Synbiobeta 2014

From five-cent synthesis to Martian DNA: Synbiobeta 2014 | Synthetic Biology | Scoop.it

Synbiobeta San Francisco 2014 is wrapping up this morning with a networking cruise in the bay that I won’t be able to join because I need to head to the airport in a few hours.

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New Tool Could Help Reshape the Limits of Synthetic Biology

New Tool Could Help Reshape the Limits of Synthetic Biology | Synthetic Biology | Scoop.it
 Developed at NYU Langone Medical Center, the “telomerator” reshapes synthetic yeast chromosome into more flexible, realistic form, redefining what geneticists can build
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Circular Chromosomes Straightened

Circular Chromosomes Straightened | Synthetic Biology | Scoop.it

Synthetic biologists often work with circular chromosomes to engineer genetic material because they’re stable and easy to manipulate, but they don’t resemble the natural shape of chromosomes in eukaryotes. Reporting in PNAS this week (November 5), Jef Boeke of NYU Langone Medical Center and postdoc Leslie Mitchell designed a tool, which they dubbed the telomerator, that straightens circular yeast chromosomes and adds telomeres to either end.

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Synthetic biology could be big boost to interplanetary space travel

Synthetic biology could be big boost to interplanetary space travel | Synthetic Biology | Scoop.it

Genetically engineered microbes could help make manned missions to Mars, the moon and other planets more practical, according to a new analysis by UC Berkeley and NASA scientists.

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New Tool Could Help Reshape The Limits Of Synthetic Biology

NYU Langone yeast geneticists report they have developed a novel tool -- dubbed "the telomerator" -- that could redefine the limits of synthetic biology and advance how successfully living things can be engineered or constructed in the laboratory based on an organism's genetic, chemical base-pair structure.

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Biohackers of Singapore: Promise of a Biotech Revolution?

Biohackers of Singapore: Promise of a Biotech Revolution? | Synthetic Biology | Scoop.it

Among the Maker Movement, there are those that deal with more exotic materials and craft. Who are they? They’re the biohackers, designing and altering the essence of life itself. Silicon, plastic and metals are just some of the materials makers use. But what about the more exotic? Some Makers code with carbon. More specifically, with DNA, most ancient and elegant of codes.

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Artificial cell with multiple compartments could improve drug delivery

Artificial cell with multiple compartments could improve drug delivery | Synthetic Biology | Scoop.it

Imperial scientists have made a new artificial cell that can compartmentalise its contents and set off a sequence of key biological processes.

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The revolution in biology is here, now

The revolution in biology is here, now | Synthetic Biology | Scoop.it

The BioFabricate summit in New York rearranged my thinking. BioFabricate was about the intersection of manufacturing and biology: not just “we can make cool new microbes,” but using biology to manufacture products for the real world. Biological products have always seemed far off. But they’re not: the revolution in biology is clearly here now, just unevenly distributed.

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Towards synthetic biological approaches to resource utilization on space missions

Towards synthetic biological approaches to resource utilization on space missions | Synthetic Biology | Scoop.it

This paper demonstrates the significant utility of deploying non-traditional biological techniques to harness available volatiles and waste resources on manned missions to explore the Moon and Mars. Compared with anticipated non-biological approaches, it is determined that for 916 day Martian missions: 205 days of high-quality methane and oxygen Mars bioproduction withMethanobacterium thermoautotrophicum can reduce the mass of a Martian fuel-manufacture plant by 56%; 496 days of biomass generation with Arthrospira platensis and Arthrospira maxima on Mars can decrease the shipped wet-food mixed-menu mass for a Mars stay and a one-way voyage by 38%; 202 days of Mars polyhydroxybutyrate synthesis with Cupriavidus necator can lower the shipped mass to three-dimensional print a 120 m3 six-person habitat by 85% and a few days of acetaminophen production with engineered Synechocystis sp. PCC 6803 can completely replenish expired or irradiated stocks of the pharmaceutical, thereby providing independence from unmanned resupply spacecraft that take up to 210 days to arrive. Analogous outcomes are included for lunar missions. Because of the benign assumptions involved, the results provide a glimpse of the intriguing potential of ‘space synthetic biology’, and help focus related efforts for immediate, near-term impact.

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Bringing Synthetic Biology to (Freeze-dried) Paper

Bringing Synthetic Biology to (Freeze-dried) Paper | Synthetic Biology | Scoop.it

Paper-based diagnostics such as pregnancy tests have been around for a while, but over the past few years researchers have been working to answer more complex biological questions. Now, synthetic biologists have developed portable, inexpensive, and accurate paper-based tests that could one day serve as diagnostics for Ebola and other diseases. 

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New device could make large biological circuits practical

New device could make large biological circuits practical | Synthetic Biology | Scoop.it

Innovation from MIT could allow many biological components to be connected to produce predictable effects.

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Arantzazu's curator insight, November 25, 3:04 PM

Un paso más en el desarrollo de método alternativos de reemplazo según el principio de las 3'R de Russell

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Developments in the tools and methodologies of synthetic biology

Synthetic biology is principally concerned with the rational design and engineering of biologically based parts, devices or systems. However, biological systems are generally complex and unpredictable and are therefore intrinsically difficult to engineer. In order to address these fundamental challenges, synthetic biology is aiming to unify a ‘body of knowledge’ from several foundational scientific fields, within the context of a set of engineering principles. This shift in perspective is enabling synthetic biologists to address complexity, such that robust biological systems can be designed, assembled and tested as part of a biological design cycle. The design cycle takes a forward-design approach in which a biological system is specified, modeled, analyzed, assembled and its functionality tested. At each stage of the design cycle an expanding repertoire of tools is being developed. In this review we highlight several of these tools in terms of their applications and benefits to the synthetic biology community.

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Biologists Engineer A Three-Gene Optogenetic System

Biologists Engineer A Three-Gene Optogenetic System | Synthetic Biology | Scoop.it

New blue-light-active protein offers researchers ability to turn on genes with red, blue, and ultraviolet-B light

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Building proteins to counteract cancer

Building proteins to counteract cancer | Synthetic Biology | Scoop.it

Karmella Haynes wants to help the body fight cancer by designing proteins to stop the disease.

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Q&A: Synthetic biology and space

Q&A: Synthetic biology and space | Synthetic Biology | Scoop.it

Can synthetic biology help improve manned space missions to the Moon and Mars? Space missions are expensive and technologies for aerospace travel are continuously evaluated for cost, relevance and safety. We chatted to Dr Amor Menezes and colleagues about their recent Review article – published in Journal of the Royal Society Interface – which looks at how current biological techniques and future progress in synthetic biology can improve existing and develop new technology for efficient space travel.

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How Canada is poised to revolutionize synthetic biology

How Canada is poised to revolutionize synthetic biology | Synthetic Biology | Scoop.it

Canada’s research and business communities have an opportunity to become world leaders in a burgeoning field that is fast shaping how we deal with everything from climate change to global food security and the production of lifesaving medications. The science of synthetic biology has the transformative capacity to equip us with novel technology tools and products to build a more sustainable society, while creating new business and employment opportunities for the economy of tomorrow.  

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Connecting the microcosmos and the macro world

Connecting the microcosmos and the macro world | Synthetic Biology | Scoop.it
Christina Agapakis explores the microbiological matrix that binds everything from pecorino to people.

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Transforming toxic waste into green energy

Transforming toxic waste into green energy | Synthetic Biology | Scoop.it

Emerging graduate research at Concordia seeks to turn pulp mills into dynamic biorefineries

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Concordia research harnesses the power of opium poppies

Concordia research harnesses the power of opium poppies | Synthetic Biology | Scoop.it

An innovative approach to painkiller production could lessen Canada’s dependence on foreign supplies.

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