The International Genetically Engineered Machine (iGEM) competition is fast paced, and teams need a good plan and quick access to materials if they are going to be successful. IDT has been a regular sponsor of iGEM teams and would like to offer our help and insights to this year’s teams, as well as provide some free DNA to get you started. In this webinar, we will introduce you to gBlocks® Gene Fragments. We will present some examples of past iGEM projects to illustrate how gBlocks Gene Fragments can make your project a success. Finally, we will explain how to order your gene fragments and how to take advantage of the exclusive offer for 2015 iGEM teams.
If you grew up playing with plug-and-play electronics kits (or, these days, the magical redstone in Minecraft), you’ll be familiar with the brunt literal-mindedness of circuit boards. Whatever elaborate construct of LEDs, buzzers, and motors you come up with has to rely on just two input conditions: is there electricity, or no?
NON-SCIENTISTS GENERALLY think of “circadian clock” as a metaphoric term. There’s nothing literally ticking away inside the human body, helping align it to the regular cycle of day and night. But synthetic biologists from Harvard Medical School (HMS) and the Wyss Institute for Biologically Inspired Engineering have created something just that tangible: a transplantable, bioengineered 24-hour clock, which functioned by itself after being inserted into a bacterium that doesn’t typically have a circadian rhythm.
Over the past decade, the development of fast and affordable technologies for DNA sequencing and synthesis and a growing understanding of complex biological systems have opened the door to a new approach to biology. It has become possible, at least in principle, to standardize, design, and build from scratch biological parts—and assemble them into systems that perform specific functions in a predictable and reliable way. This new field is synthetic biology,defined by the European Commission as “the application of science, technology and engineering to facilitate and accelerate the design, manufacture and/or modification of genetic materials in living organisms.”
Science policy experts have called for urgent measures to be put in place to prevent strains of yeast that are capable of producing opiate drugs from falling into the hands of criminals. The prospect of ‘home-brewed heroin’ has been raised after new research describes how a key enzyme in the pathway from glucose to morphine and other opiates has for the first time been successfully expressed in yeast. The finding means that the complete biosynthetic pathway for the family of compounds that includes codeine and morphine is close to being achieved in yeast. However, opinion on the potential dangers to society of the new technology is divided, with other experts suggesting that there are unlikely to be major problems.
Synthetic biology could be seen as a natural development of traditional biotechnology and applied genetics. However, the exuberant culture that it has embraced should ensure it has a very bright future.
1,4-BUTANEDIOL ISN’T EXACTLY the flashiest product on the market: with a four-carbon chain bounded by alcohol groups, the thick, colorless liquid is one of those “industrial chemicals” that makes the eyes glaze over. But the diminutive molecule is worth some serious cash, with an estimated global market cap of $2 billion. Ultimately, 1,4-butanediol, also known as BDO, facilitates the production of a range of plastics, polyurethanes, and elastic fibers, making everything from skateboards to Spandex possible.
UC Berkeley researchers have developed an easy way to put bacteria under a molecular lock and key in order to contain its accidental spread. The method involves a series of genetic mutations that render the microbe inactive unless the right molecule is added to enable its viability.
Five years ago, the graduate students behind a secretive startup called Bolt Threads set out to replicate the unique chemical properties of spider silk, an almost magically flexible and durable material that’s in some ways as strong as steel. One of the first things they did was buy a batch of Nephila spiders—the common golden silk orb-weavers—from an insect dealer in Florida. Then they let the spiders spin their webs all over the company’s first office at the University of California at San Francisco. One day a well-known UCSF molecular biologist walked in, saw a spider hanging in a doorway, and ran away screaming.
Another step forward has just been taken in the area of synthetic biology. Research teams from Inserm and CNRS (French National Centre for Scientific Research) Montpellier, in association with Montpellier Regional University Hospital and Stanford University, have transformed bacteria into “secret agents” that can give warning of a disease based solely on the presence of characteristic molecules in the urine or blood. To perform this feat, the researchers inserted the equivalent of a computer programme into the DNA of the bacterial cells. The bacteria thus programmed detect the abnormal presence of glucose in the urine of diabetic patients. This work, published in the journal ScienceTranslationalMedicine, is the first step in the use of programmable cells for medical diagnosis
Genetically engineered bacterial cells that produce high volumes of proteins are the workhorses of synthetic biology. However, churning out an endless stream of foreign proteins can exhaust cells’ resources. Is there a way to lighten the load?
Researchers at The University of Manchester have made a significant breakthrough in the development of synthetic pathways that will enable renewable biosynthesis of the gas propane. This research is part of a programme of work aimed at developing the next generation of biofuels.
Sharing your scoops to your social media accounts is a must to distribute your curated content. Not only will it drive traffic and leads through your content, but it will help show your expertise with your followers.
How to integrate my topics' content to my website?
Integrating your curated content to your website or blog will allow you to increase your website visitors’ engagement, boost SEO and acquire new visitors. By redirecting your social media traffic to your website, Scoop.it will also help you generate more qualified traffic and leads from your curation work.
Distributing your curated content through a newsletter is a great way to nurture and engage your email subscribers will developing your traffic and visibility.
Creating engaging newsletters with your curated content is really easy.