Researchers have genetically engineered trees that will be easier to break down to produce paper and biofuel, a breakthrough that will mean using fewer chemicals, less energy and creating fewer environmental pollutants.
Synthetic genetic circuitry created by researchers at Rice University is helping them see, for the first time, how to regulate cell mechanisms that degrade the misfolded proteins implicated in Parkinson’s, Huntington’s and other diseases.
Science magazine has just published the latest tour de force in building genetic machinery from the ground-up since Mycoplasma laboratorium (“Mycoplasma of the laboratory”), dubbed Synthia by some. M. lab, the “synthetic cell,” represented a major milestone in the synthesis of functional DNA, which was announced just four years ago . Craig Venter’s group from the JCVI had reported the complete chemical synthesis of a chromosome that was able to support living, bacterial Mycoplasma genitalium cells.
Dr Adam Clore, Manager of Synthetic Biology Design, Support, and Biosecurity at Integrated DNA Technologies, will participate in the "Gene and Genome Design and Synthesis" session at SynBioBeta on Thursday, April 3 in London.
In the year they devote to U.Va.’s International Genetically Engineered Machine (iGEM) competition, Team Virginia members maintain a hectic pace. They have just 12 months to familiarize themselves with the techniques of synthetic biology, identify new and potentially useful qualities they can add to a biological system, and design and produce this new system using standardized genetic building blocks from the iGEM Registry of Standard Biological Parts or by creating their own.
Researchers with the U.S. Department of Energy (DOE)’s Joint BioEnergy Institute (JBEI), a multi-institutional partnership led by Berkeley Lab, have identified the genetic origins of a microbial resistance to ionic liquids and successfully introduced this resistance into astrain of E. coli bacteria for the production of advanced biofuels. The ionic liquid resistance is based on a pair of genes discovered in a bacterium native to a tropical rainforest in Puerto Rico.
With such ambitious goals as helping cure cancer and eradicating pervasive disease, some of the most talented scientists in the country from the emerging field of synthetic biology are breaking new ground at Northwestern University.
The gut is a dark and hidden world. We usually only know what’s happening within it when something goes badly wrong. But there are trillions of microbes in our guts; with their first-hand experience, they’re perfectly positioned to tell us about what’s going on inside ourselves. Pamela Silver from Harvard Medical School is now training them to do that. Her team is transforming gut bacteria into journalists—microscopic reporters who cover the bowel beat.
As chief technology officer of Autodesk, Jeff Kowalski, 47, is responsible for shaping the US-based design software maker's long-term technology vision and has a ringside view to some cutting-edge technology in the works, including 4D printing. In a telephonic interview to ET's Jarshad NK, Kowalski talks about the pitfalls of predicting the future, the blurring of lines between the living and material world and why 3D printing, an area in which Autodesk is one of the pioneers, is not likely to replace traditional manufacturing.
A technology for engineering human cells as therapies has been developed by scientists. The the technology becomes activated only in diseased tissues. It sits on the surface of a cell and can be programmed to sense specific external factors. For example, the engineered cell could detect big, soluble protein molecules that indicate that it's next to a tumor. When the biosensor detects such a factor, it sends a signal into the engineered cell's nucleus to activate a gene expression program, such as the production of tumor-killing proteins or chemicals.
An international team of scientists led by Jef Boeke, PhD, director of NYU Langone Medical Center’s Institute for Systems Genetics, has synthesized the first functional chromosome in yeast, an important step in the emerging field of synthetic biology, designing microorganisms to produce novel medicines, raw materials for food, and biofuels.
The last decade has witnessed unprecedented growth in the field of Synthetic Biology. A dramatic increase in the ability to synthesize long and complex sequences of double stranded DNA quickly and inexpensively has allowed the construction entire genetic pathways and even complete bacterial genomes. This advance combined with the discovery of new methods to modify genomes using technologies such as TALENS and CRISPR have allowed large scale, rapid modification of organisms, greatly expanding development in fields such as pharmaceuticals, biofuels, crop design, and vaccine development. This talk will explore the development and implementation of these techniques as well as highlight advances in research made possible by these technologies.
Researchers at the Georgia Institute of Technology and the Joint BioEnergy Institute have engineered a bacterium to synthesize pinene, a hydrocarbon produced by trees that could potentially replace high-energy fuels, such as JP-10, in missiles and other aerospace applications. With improvements in process efficiency, the biofuel could supplement limited supplies of petroleum-based JP-10, and might also facilitate development of a new generation of more powerful engines.
Fresh banana, a waft of flowers, blueberry: the scents in Shota Atsumi's laboratory in the UC Davis Department of Chemistry are a little sweeter than most. That's because Atsumi and his team are engineering bacteria to make esters — molecules widely used as scents and flavorings, and also as basic feedstock for chemical processes from paints to fuels.