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Fast and Accurate Assembly of a 2.1 kb Gene

Fast and Accurate Assembly of a 2.1 kb Gene | Synthetic Biology | Scoop.it

gBlocks™ Gene Fragments + Gibson Assembly™ Master Mix

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Synthetic Biology
All about the growing field of synthetic biology
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iGEM Success Using High Quality Gene Fragments

The International Genetically Engineered Machine (iGEM) competition is fast paced, and teams need a good plan and quick access to materials if they are going to be successful. IDT has been a regular sponsor of iGEM teams and would like to offer our help and insights to this year’s teams, as well as provide some free DNA to get you started. In this webinar, we will introduce you to gBlocks® Gene Fragments. We will present some examples of past iGEM projects to illustrate how gBlocks Gene Fragments can make your project a success. Finally, we will explain how to order your gene fragments and how to take advantage of the exclusive offer for 2015 iGEM teams.

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Programming an Abundant Human Gut Microbe

Programming an Abundant Human Gut Microbe | Synthetic Biology | Scoop.it

If you grew up playing with plug-and-play electronics kits (or, these days, the magical redstone in Minecraft), you’ll be familiar with the brunt literal-mindedness of circuit boards. Whatever elaborate construct of LEDs, buzzers, and motors you come up with has to rely on just two input conditions: is there electricity, or no?

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Nicola Patron leads standard for the assembly of DNA parts for plant synthetic biology.

Nicola Patron leads standard for the assembly of DNA parts for plant synthetic biology. | Synthetic Biology | Scoop.it

Dr Nicola Patron has led development of the first common standard for the assembly of DNA parts for plant synthetic biology.

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Microfluidic Device Mixes And Matches DNA For Synthetic Biology

Microfluidic Device Mixes And Matches DNA For Synthetic Biology | Synthetic Biology | Scoop.it

Device assembles rings of DNA and plugs them into cells

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Harvard synthetic biology researchers built a transplantable circadian clock

Harvard synthetic biology researchers built a transplantable circadian clock | Synthetic Biology | Scoop.it

NON-SCIENTISTS GENERALLY think of “circadian clock” as a metaphoric term. There’s nothing literally ticking away inside the human body, helping align it to the regular cycle of day and night. But synthetic biologists from Harvard Medical School (HMS) and the Wyss Institute for Biologically Inspired Engineering have created something just that tangible: a transplantable, bioengineered 24-hour clock, which functioned by itself after being inserted into a bacterium that doesn’t typically have a circadian rhythm.   

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Training for synthetic biology jobs in the new bioeconomy

Training for synthetic biology jobs in the new bioeconomy | Synthetic Biology | Scoop.it

Over the past decade, the development of fast and affordable technologies for DNA sequencing and synthesis and a growing understanding of complex biological systems have opened the door to a new approach to biology. It has become possible, at least in principle, to standardize, design, and build from scratch biological parts—and assemble them into systems that perform specific functions in a predictable and reliable way. This new field is synthetic biology,defined by the European Commission as “the application of science, technology and engineering to facilitate and accelerate the design, manufacture and/or modification of genetic materials in living organisms.”

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Find the Right DNA Tool for the Job – Accelerate Synthetic Biology with IDT at ASM 2015

Find the Right DNA Tool for the Job – Accelerate Synthetic Biology with IDT at ASM 2015 | Synthetic Biology | Scoop.it

IDT demonstrates how to enhance research methods with innovative new DNA tools 

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Opiate-producing yeast raises spectre of 'home-brewed heroin'

Opiate-producing yeast raises spectre of 'home-brewed heroin' | Synthetic Biology | Scoop.it

Science policy experts have called for urgent measures to be put in place to prevent strains of yeast that are capable of producing opiate drugs from falling into the hands of criminals. The prospect of ‘home-brewed heroin’ has been raised after new research describes how a key enzyme in the pathway from glucose to morphine and other opiates has for the first time been successfully expressed in yeast. The finding means that the complete biosynthetic pathway for the family of compounds that includes codeine and morphine is close to being achieved in yeast. However, opinion on the potential dangers to society of the new technology is divided, with other experts suggesting that there are unlikely to be major problems.

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Biologists to engineer bacteria for vaccine delivery

Biologists to engineer bacteria for vaccine delivery | Synthetic Biology | Scoop.it

An eight million Euro project has been launched with the aim of engineering bacteria to deliver vaccines against antibiotic-resistant infections.

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Tiny light bulb in a cell could improve biological devices

Tiny light bulb in a cell could improve biological devices | Synthetic Biology | Scoop.it

Scientists have developed a tiny fluorescing light bulb for detecting potential problems in biological devices.

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Engineered Bacteria Shine Light On Air Pollution

Engineered Bacteria Shine Light On Air Pollution | Synthetic Biology | Scoop.it

Biosensors: A pollutant-detecting device contains bioluminescent bacteria that glow if the surrounding air contains toxic chemicals

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Synthesizing tomorrow

Synthetic biology could be seen as a natural development of traditional biotechnology and applied genetics. However, the exuberant culture that it has embraced should ensure it has a very bright future.

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Mobilizing the Planet’s Genetic Diversity with Synthetic Biology

Mobilizing the Planet’s Genetic Diversity with Synthetic Biology | Synthetic Biology | Scoop.it

1,4-BUTANEDIOL ISN’T EXACTLY the flashiest product on the market: with a four-carbon chain bounded by alcohol groups, the thick, colorless liquid is one of those “industrial chemicals” that makes the eyes glaze over. But the diminutive molecule is worth some serious cash, with an estimated global market cap of $2 billion. Ultimately, 1,4-butanediol, also known as BDO, facilitates the production of a range of plastics, polyurethanes, and elastic fibers, making everything from skateboards to Spandex possible.

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Harpal S.sandhu's curator insight, June 11, 6:39 PM

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Virginia Tech scientist develops model for robots with bacterial brains

Virginia Tech scientist develops model for robots with bacterial brains | Synthetic Biology | Scoop.it

Forget the Vulcan mind-meld of the Star Trek generation — as far as mind control techniques go, bacteria is the next frontier.

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Denis Malyshev, The DNA Amplifier

Denis Malyshev, The DNA Amplifier | Synthetic Biology | Scoop.it

Synthetic biologist is expanding the genetic alphabet to create unnatural proteins

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Scientists use molecular ‘lock and key’ for potential control of GMOs

Scientists use molecular ‘lock and key’ for potential control of GMOs | Synthetic Biology | Scoop.it

UC Berkeley researchers have developed an easy way to put bacteria under a molecular lock and key in order to contain its accidental spread. The method involves a series of genetic mutations that render the microbe inactive unless the right molecule is added to enable its viability.

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A Bay Area Startup Spins Lab-Grown Silk

A Bay Area Startup Spins Lab-Grown Silk | Synthetic Biology | Scoop.it

Five years ago, the graduate students behind a secretive startup called Bolt Threads set out to replicate the unique chemical properties of spider silk, an almost magically flexible and durable material that’s in some ways as strong as steel. One of the first things they did was buy a batch of Nephila spiders—the common golden silk orb-weavers—from an insect dealer in Florida. Then they let the spiders spin their webs all over the company’s first office at the University of California at San Francisco. One day a well-known UCSF molecular biologist walked in, saw a spider hanging in a doorway, and ran away screaming.

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Intelligent bacteria for detecting disease

Intelligent bacteria for detecting disease | Synthetic Biology | Scoop.it

Another step forward has just been taken in the area of synthetic biology. Research teams from Inserm and CNRS (French National Centre for Scientific Research) Montpellier, in association with Montpellier Regional University Hospital and Stanford University, have transformed bacteria into “secret agents” that can give warning of a disease based solely on the presence of characteristic molecules in the urine or blood. To perform this feat, the researchers inserted the equivalent of a computer programme into the DNA of the bacterial cells. The bacteria thus programmed detect the abnormal presence of glucose in the urine of diabetic patients. This work, published in the journal Science TranslationalMedicine, is the first step in the use of programmable cells for medical diagnosis

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Microdomains set the stage for breakthroughs in study of human disease

Microdomains set the stage for breakthroughs in study of human disease | Synthetic Biology | Scoop.it

J. Andrew MacKay builds on his team’s attempt to control polypeptide-based structures.

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Drugs: Regulate 'home-brew' opiates

Drugs: Regulate 'home-brew' opiates | Synthetic Biology | Scoop.it

The research community and the public require a fast, flexible response to the synthesis of morphine by engineered yeasts, urge Kenneth Oye, Tania Bubela and J. Chappell H. Lawson.

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Engineering Efficiency

Engineering Efficiency | Synthetic Biology | Scoop.it

Genetically engineered bacterial cells that produce high volumes of proteins are the workhorses of synthetic biology. However, churning out an endless stream of foreign proteins can exhaust cells’ resources. Is there a way to lighten the load?

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Scientists a step closer to developing renewable propane

Scientists a step closer to developing renewable propane | Synthetic Biology | Scoop.it

Researchers at The University of Manchester have made a significant breakthrough in the development of synthetic pathways that will enable renewable biosynthesis of the gas propane. This research is part of a programme of work aimed at developing the next generation of biofuels.

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Microbes Engineered to Prevent Obesity

Microbes Engineered to Prevent Obesity | Synthetic Biology | Scoop.it

Genetically engineered bacteria ward off obesity in mice, showing how the microbiome could be used treat chronic diseases in people.

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Synthetic biologists seek standards for nascent field

Synthetic biologists seek standards for nascent field | Synthetic Biology | Scoop.it

Common language and methods are needed to fulfil biofactory dream.

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