SynBioFromLeukipp...
Follow
Find
72.9K views | +9 today
SynBioFromLeukipposInstitute
Your new post is loading...
Your new post is loading...
Scooped by Socrates Logos
Scoop.it!

A New Approach to an Old Pr... [Cold Spring Harb Symp Quant Biol. 2011] - PubMed - NCBI

more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

Proteins are first, structurally speaking « Synth in Tune

Proteins are first, structurally speaking « Synth in Tune | SynBioFromLeukipposInstitute | Scoop.it

"Structure has always been the next frontier. Computational biologists tend to talk about the twilight zone to speak about this region of the sequence space of proteins where molecular structures are still vaguely known and susceptible of further refinement. A realm of sequences where, as in Plato’s Cave, appearances are deceiving and inference by homology needs necessarily to be ruled out...."

more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

Synthetic Biology and its Promise

Synthetic Biology and its Promise | SynBioFromLeukipposInstitute | Scoop.it
Synthetic Biology is going to be huge all over the world very soon. No wonder, the promise is incredible. According to Jeurgen Pleiss, possible applications of synthetic biology include:

1. Gene...
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

I Heard You Like Feedback Loops | Oscillator, Scientific American Blog Network

I Heard You Like Feedback Loops | Oscillator, Scientific American Blog Network | SynBioFromLeukipposInstitute | Scoop.it

"In some labs, biology and computer science are converging. On the one hand, computer scientists are working towards creating computer chips inspired by the circuitry of ..."

A nice news and views. Thanks Christina Agapakis.
Very interesting that you mentioned Systems Theory.
This provides in my opinion the new paradigm in science. We have moved from a reductionistic hypothesis driven science to a data driven scientific concept. Two computer developments are responsible for the paradigm change. The first is the enormous storage capacity in the cloud. We talk about a magnitude in the petabyte scale. One petabyte is equal to one quadrillion bytes or 1000 tetrabytes. This is 10exp15 bytes. Google processes about 24 petabytes per day. The second is that a huge number of computers have been connected and organized in social networks. a huge number of computers are now connected via the Internet. We now have access to the huge data- amount from many locations. In addition: We have twitter, facebook and many other social networks, which give a context for the enormous data-amount.

These changes have resulted in huge quantities of data and complex systems. We have a data flooding. This a problem normal science cannot solve. The structures of the science world were designed to fit a pre-computer age. The hypothesis method can deal with simple correlations between A and B. But the method fails if the problem becomes more complex with many factors, eg A to I or even more. This is too complex for deducing an empirical consequence.

A novel theoretical base for science has evolved. Groundbreaking theories have been published:
As you have mentioned: 1948 – Norbert Wiener: Cybernetics or Control and communication in the animal and machine.
Moreover interesting is also:
1955 – William Ross Ashby: Introduction to cybernetics.
1968 – Ludwig Bertalanffy: General System theory: Foundations, Development, Applications.
Notable further developments of systems theory are: Heinz Foerster’s second order-cybernetics, Ilya Prigogine’s work on self-organization and his systems theory concepts with thermodynamics, and Mitchell Feigenbaum’s work on chaos theory.
Systems theory is a fundament for software and thus influences the scientific method. Contemporary applications of systems theory are systems biology and synthetic biology. This philosophical movement has two components: Idealism and systems theory.
Idealism:
Idealism is based on Plato’s theory of forms (ideas). In line with this theory, cybernetics assumes that the human nervous system calculates reality. This means:
Our brain calculates a model of an object.
The human reception is the basis of the scientific method.
The key tools are mathematics and logic.
The result of this calculation is a model, which is not identical to the object.
Thus, it is impossible to achieve knowledge about the world such as it exists independent of us
Systems theory:
In systems theory, contemporary science moves from reductionism to a more holistic position. A system is a set of interacting or independent components forming an integrated whole. Systems behavior involves input, processing and output of data, and can be self-organizing and self-regulating by feedback. Ref http://bit.ly/kjOVs2 and http://bit.ly/lMbKc8

more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

DNA2.0 Integrates Synthetic Biology Open Language (SBOL) Into Gene Designer

DNA2.0 Integrates Synthetic Biology Open Language (SBOL) Into Gene Designer | SynBioFromLeukipposInstitute | Scoop.it

DNA2.0 announces the integration of the first standardized information exchange framework for synthetic biology into the company's breakthrough gene design and assembly application. Menlo Park, CA (PRWEB) December 14,...

more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

2057 The Body Michio Kaku

Part one of the 2057 series documentary made by the discovery channel with michio kaku the renowned physicist. The body episode is a fascinating look at futu...
 
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

Visions of the Future (2 of 3) The Biotech Revolution

Visions of the Future: The Biotech Revolution. 2nd part of 3 part miniseries on the BBC hosted by Michio Kaku.
 
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

Introduction to synthetic biology

EMBO global exchange lecture course Apr 16-22, 2012, Buenos Aires: "Synthetic biology operates at the interface of systems biology, engineering, computer science, and classic molecular biology..."

 
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

Interview Andrew Hessel (Host: Aldith Hunkar)

Produced by: http://www.fellermedia.nl Camera & crew: http://www.hoens.tv Hosted by Aldith Hunkar Andrew Hessel is a bioengineer. He likes to play with molec...
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

Ed Boyden: A light switch for neurons

http://www.ted.com Ed Boyden shows how, by inserting genes for light-sensitive proteins into brain cells, he can selectively activate or de-activate specific...
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

OEC - Synthetic Biology and Genetic Engineering

SynBio and ethics

more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

Berkeley hosts manufacturing brainstorm

Berkeley hosts manufacturing brainstorm | SynBioFromLeukipposInstitute | Scoop.it
Leaders from academia, government and industry gathered at UC Berkeley Monday to discuss partnership strategies to re-establish the United States as a global leader in advanced manufacturing.
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

Fluorescent probes increase understanding of bacterium's electron transfer

Fluorescent probes increase understanding of bacterium's electron transfer | SynBioFromLeukipposInstitute | Scoop.it
(PhysOrg.com) -- When it comes to transporting a cell's valuable electrons, the metal-reducing microbe Shewanella oneidensis only trusts stable, mature proteins, according to scientists at Pacific Northwest National Laboratory.
 
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

Synthetic biology: Cellular xDNA readers

{Nature Publishing via BioPortfolio}...
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

The technical side of cell factories « Synth in Tune

The technical side of cell factories « Synth in Tune | SynBioFromLeukipposInstitute | Scoop.it

"Cell factories are envisioned as future workhorse manufacturers of pharmaceuticals, biofuels and biomaterials. Two main engines work in coordination inside cell factory’s machinery: gene regulatory networks and biochemical pathways. Both networks are amenable to an engineering approach for their modeling, design and validation. Therefore, off-the-shelf implementations of these bioengineering appliances are becoming more widespread with the advent of rational synthetic biology. Take for instance a cell factory for the synthesis of natural products or secondary metabolites..."

more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

Gene Editing for a Better "Franken-cell" | The Promethean Cell | Learn Science at Scitable

Gene Editing for a Better "Franken-cell" | The Promethean Cell | Learn Science at Scitable | SynBioFromLeukipposInstitute | Scoop.it
I have referred to iPSCs in a previous post as 'franken-cells' and questioned whether they can offer important biological insights to the world. In this post, I'll eat my words and offer some examples where their artificiality is an asset.
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

An Open Letter From Internet Engineers to the U.S. Congress | Electronic Frontier Foundation

An Open Letter From Internet Engineers to the U.S. Congress | Electronic Frontier Foundation | SynBioFromLeukipposInstitute | Scoop.it

Modern Systems Theory based science needs an open free accesiable data pool. Thus SOPA and PIPA needs to be stopped!

 
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

TRADE NEWS: Yale University Adopts Multiple Agilent Platforms for Integrative Biology Research at New West Campus

TRADE NEWS: Yale University Adopts Multiple Agilent Platforms for Integrative Biology Research at New West Campus | SynBioFromLeukipposInstitute | Scoop.it

Yale encompass integrative biology, #SynBio + quantitative proteomics to gain insights into disease mechanisms

more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

Could hackers develop a 'computer virus' to infect the human mind?

Could hackers develop a 'computer virus' to infect the human mind? | SynBioFromLeukipposInstitute | Scoop.it
Silicon valley synthetic biology expert Andrew Kessel says that genetics technology is accelerating 'faster than computer technology' - and warns that hackers might use it to bend human minds.
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

SBOL Developers - Synthetic Biology Open Language

SBOL Developers - Synthetic Biology Open Language | SynBioFromLeukipposInstitute | Scoop.it
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

When biologists become designers of humans, then what? | SmartPlanet

When biologists become designers of humans, then what? | SmartPlanet | SynBioFromLeukipposInstitute | Scoop.it
As the tools and knowledge base for engineering genetic codes advance, the tools for designing the end product have limited usefulness.
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

DNA Hackers: Synthetic biology weaponized virus, 0day exploit to infect your brain?

DNA Hackers: Synthetic biology weaponized virus, 0day exploit to infect your brain? | SynBioFromLeukipposInstitute | Scoop.it
Bioengineers and security futurists are warning that the day is coming when criminals and bioterrorists hunt for vulnerabilities that will give a new meaning to 0day exploits.
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

Star Wars-inspired bacterium provides glimpse into life | Machines Like Us

Star Wars-inspired bacterium provides glimpse into life | Machines Like Us | SynBioFromLeukipposInstitute | Scoop.it
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

Synthetic Biology Institute at UC Berkeley - Home

Synthetic Biology Institute at UC Berkeley - Home | SynBioFromLeukipposInstitute | Scoop.it
more...
No comment yet.
Scooped by Socrates Logos
Scoop.it!

Targeted Protein Degradation of Outer Membrane Decaheme Cytochrome MtrC Metal Reductase in Shewanella oneidensis MR-1 Measured Using Biarsenical Probe CrAsH-EDT2 - Biochemistry (ACS Publications)

Targeted Protein Degradation of Outer Membrane Decaheme Cytochrome MtrC Metal Reductase in Shewanella oneidensis MR-1 Measured Using Biarsenical Probe CrAsH-EDT2 - Biochemistry (ACS Publications) | SynBioFromLeukipposInstitute | Scoop.it
more...
No comment yet.