There is a swirling controversy regarding the suspicion that medications prescribed for the treatment of ADHD (attention-deficit/hyperactivity disorder) primarily act to control disruptive behavior as opposed to having primary effects on the...
Clearly written for the parent and educator audience trying to understand how medications actually work to improve performance of children with ADHD.--Lou
Excerpt: "....Dr. Anna Smith explains their findings: "We show here that the stimulant methylphenidate acts quickly with immediate effects upon performance on a timing task we know children with ADHD find challenging. Crucially however, acute doses of either methylphenidate or the non-stimulant atomoxetine increase brain activation in the frontal lobes, typically under-recruited in children with ADHD, so that these key under-functioning frontal brain regions operate at the normal levels seen in other children."
"This exciting finding suggests that both stimulants and non-stimulants share similar mechanisms of action and are both comparable in the way they normalise the activity of important frontal brain regions in children with ADHD. This could explain why both types of drug improve behaviour in children with ADHD, namely by normalizing the reduced activity in the frontal lobes that typifies the disorder," she added.
Methylphenidate and atomoxetine are interesting drugs to compare. Methylphenidate blocks both norepinephrine and dopamine transporters, while atomoxetine blocks only the norepinephrine transporter...."
Elsevier (2013, October 16). How Do ADHD Medications Work?. ScienceDaily. Retrieved October 19, 2013, from