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StemCells, Inc. Provides Update on Its Phase I/II Clinical Trial in Spinal Cord Injury

StemCells, Inc. Provides Update on Its Phase I/II Clinical Trial in Spinal Cord Injury | Stem Cells & Tissue Engineering | Scoop.it
In an interim update, presented by the study principal investigator, the company reports that the significant post-transplant gains in sensory function first reported in two patients have now been ...
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Angiogenic Properties of Human Dental Pulp Stem Cells

Angiogenic Properties of Human Dental Pulp Stem Cells | Stem Cells & Tissue Engineering | Scoop.it
Stem cells can be easily extracted from the tooth soft tissue and are termed dental pulp stem cells (DPSC). These stem cells share unique characteristic features with other mesenchymal stem cells t...
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3D Printed Hip Replacement with Stem Cells

3D Printed Hip Replacement with Stem Cells | Stem Cells & Tissue Engineering | Scoop.it
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3D printing is becoming increasingly implemented in the operating room, with surgeons turning to the technology to create tailor-made implants for their patients.  This time, surgeons at Southampton General Hospital have 3D printed a hip joint for 71-year-old Meryl Richards and have used her own stem cells to hold it in place.

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Human Neural Precursor Cells Promote Neurologic Recovery in a Multiple Sclerosis Animal Model

Human Neural Precursor Cells Promote Neurologic Recovery in a Multiple Sclerosis Animal Model | Stem Cells & Tissue Engineering | Scoop.it
Multiple sclerosis (MS) is an autoimmune chronic inflammatory disease of the central nervous system (CNS) which involves the infiltration of immune cells into the CNS and results in demyelination ,...
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Using Induced Pluripotent Stem Cells To Model Schizophrenia In-A-Dish

Using Induced Pluripotent Stem Cells To Model Schizophrenia In-A-Dish | Stem Cells & Tissue Engineering | Scoop.it
A research team, lead by Dr. Fred Gage from the Salk Institute, used induced pluripotent stem cells (iPSCs) to generate an in-vitro model of Schizophrenia (SZ). In the study, published in Molecular...
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Bioprinting a 3D Liver-Like Device to Detoxify the Blood

Bioprinting a 3D Liver-Like Device to Detoxify the Blood | Stem Cells & Tissue Engineering | Scoop.it
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"Nanoengineers at the University of California, San Diego have developed a 3D-printed device inspired by the liver to remove dangerous toxins from the blood. The device, which is designed to be used outside the body – much like dialysis – uses nanoparticles to trap pore-forming toxins that can damage cellular membranes and are a key factor in illnesses that result from animal bites and stings, and bacterial infections" (From www.mdtmag.com). 

Read the full paper: 

http://www.nature.com/ncomms/2014/140508/ncomms4774/full/ncomms4774.html


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One step towards Spiderman

One step towards Spiderman | Stem Cells & Tissue Engineering | Scoop.it
A new study published in Nature communications describes, for the first time, the full genome sequencing of the spider. The research team focused on two types of spiders representing two of the thr...
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Growing a heart: Divya Ramamoorthy at TEDxYouth@Austin

Growing a heart: Divya Ramamoorthy at TEDxYouth@Austin | Stem Cells & Tissue Engineering | Scoop.it
The journey of generating heart tissues is riddled with "mad scientist selfies." It is a long journey, full of failure, accompanied by only the occasional—remarkably exciting!—success. Divya's love...
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A very nice and energetic talk!

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RIKEN Makes Verdict on Two Problematic Stem Cell Papers Final

RIKEN Makes Verdict on Two Problematic Stem Cell Papers Final | Stem Cells & Tissue Engineering | Scoop.it
RIKEN Makes Verdict on Two Problematic Stem Cell Papers FinalRIKEN has decided against reopening an investigation into two stem cell papers that concluded that the lead author, Haruko Obokata of RI...
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Using Exosomes For Regenerative Medicine

Using Exosomes For Regenerative Medicine | Stem Cells & Tissue Engineering | Scoop.it
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Exosomes are extracellular vesicles shown to participate in cell-to-cell communication and in modulation of cellular immunity. It was hypothesized that the effect stem cells have on neighbouring disease or injured cells is via the release of exosomes that contain proteins, bio-active lipids and nucleic acids. This paracrine hypothesis drove researchers to investigate whether instead of using stem cells for regenerative medicine, it is possible to use their secreted, isolated exosomes (click the image for the full post).

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From Skin Cells to Sperm Progenitors

From Skin Cells to Sperm Progenitors | Stem Cells & Tissue Engineering | Scoop.it
In a new study, published in Cell Reports, researchers from Montana State University report on the successful generation of induced pluripotent stem cells (iPSCs) from infertile and healthy fertile
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Somatic Cell Nuclear Transfer from Adult Human Cells – An Additional Step Towards Therapeutic Cloning

Somatic Cell Nuclear Transfer from Adult Human Cells – An Additional Step Towards Therapeutic Cloning | Stem Cells & Tissue Engineering | Scoop.it
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Since the early days of stem cell research, stem cell scientists envisioned the potential in both research and therapeutics, of the generation of patient-specific human embryonic stem cells (hESCs) using somatic cell nuclear transfer (SCNT). During the past year, three laboratories have finally succeeded in performing this task. A year ago, Tachibana et al. created hESCs lines from embryonic and infant somatic cells. Last month, two groups reported, within two weeks of one another, generation of cloned ESCs derived from adult human somatic cells. The first group used skin from middle-aged and elderly men, whereas the second group used skin cells from a middle-aged woman with Type 1 diabetes.

In the paper published in Cell Stem Cell, Chung YG et al. reported use of a modified version of the protocol described by Tachibana et al. The researchers removed (click the image to read more).

 

LifeMap discovery  - The Embryonic Development, Regenerative Medicine and Stem Cells Database

http://discovery.lifemapsc.com/

 

 
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Yamanaka Apologizes Over Stem-Cell Research

Yamanaka Apologizes Over Stem-Cell Research | Stem Cells & Tissue Engineering | Scoop.it
Nobel Prize laureate Shinya Yamanaka, Japan's most revered stem-cell researcher, has apologized for what he described as poor record-keeping, in a surprising turn in a scandal involving the country's researchers.
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Nobel prize laureate Shinya Yamanaka apologized for poor record keeping in the STAP stem cells study.

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Herpes-loaded stem cells for the treatment of brain tumors

Herpes-loaded stem cells for the treatment of brain tumors | Stem Cells & Tissue Engineering | Scoop.it
Researchers from Harvard University, lead by Dr. Khalid Shah have developed a novel method for the treatment of brain tumors. They used mesenchymal stem cells loaded with oncolytic herpes simplex v...
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Review: Lab-on-a-chip technologies for stem cell analysis

Review: Lab-on-a-chip technologies for stem cell analysis This review in Trends in Biotechnology describes: Lab-on-a-chip technologies for stem cell cultures. Fabrication methods and materials used...
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First Autologous iPSC Bone Regeneration in Nonhuman Primate Model

First Autologous iPSC Bone Regeneration in Nonhuman Primate Model | Stem Cells & Tissue Engineering | Scoop.it
Induced pluripotent stem cell (iPSC)-based cell therapies hold great promise for regenerative medicine, however they also carry a higher risk for tumor formation, compared to autologous mesenchymal...
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GEN | Magazine Articles: Bioprinting: From Patches to Parts

GEN | Magazine Articles: Bioprinting: From Patches to Parts | Stem Cells & Tissue Engineering | Scoop.it
As three-dimensional fabrication technology improves,
applications promise to repair, regenerate, and even
replace native tissues.
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Stem/Progenitor Cells in Liver Development, Homeostasis, Regeneration, and Reprogramming

Stem/Progenitor Cells in Liver Development, Homeostasis, Regeneration, and Reprogramming | Stem Cells & Tissue Engineering | Scoop.it
This review in Cell Stem Cell journal summarizes recent advancements in the study of liver stem/progenitor cells, also termed hepatoblasts. It discusses their role during liver development, the mec...
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Exploring Hematopietic Stem Cells In Their Bone Marrow Niche

Exploring Hematopietic Stem Cells In Their  Bone Marrow Niche | Stem Cells & Tissue Engineering | Scoop.it
Hematopoietic stem cells (HSCs) are usually located in the bone marrow, where blood cell development takes place. Other cell types such as mesenchymal stem cells, adipocytes, adventitial reticular ...
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What are the differences between aged and young stem cells?

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Researchers from Vienna, Austria have published an epigenetic profiling of young and aged hematopoietic stem cells (HSCs) in a new study, published this month in Cell Stem Cell journal. 

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Transient acid treatment cannot induce neonatal somatic cells to become pluripotent stem cells

Transient acid treatment cannot induce neonatal somatic cells to become pluripotent stem cells | Stem Cells & Tissue Engineering | Scoop.it
Transient acid treatment cannot induce neonatal somatic cells to become pluripotent stem cells - See more at:
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Accusations pile up amid Japan’s stem-cell controversy

Accusations pile up amid Japan’s stem-cell controversy | Stem Cells & Tissue Engineering | Scoop.it
Scientists under scrutiny as members of investigating committee are accused of irregularities in their own research.
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It appears that four of the six members of a Japanese committee that found misconduct in STAP stem cells studies, are now facing allegations of irregularities in their own published work.

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Tissue Engineering In The Battlefield - Kit Parker at TEDxNashville

Tissue Engineering In The Battlefield - Kit Parker at TEDxNashville | Stem Cells & Tissue Engineering | Scoop.it
Kit Parker researches cardiac cell biology and tissue engineering, traumatic brain injury, and biological applications of micro- and nanotechnologies. He is ...
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Cardiac Fibroblasts - A Two-edged Sword?

Cardiac Fibroblasts - A Two-edged Sword? | Stem Cells & Tissue Engineering | Scoop.it
In many cardiac pathologies, cardiac muscle is severely impaired and is replaced by a scar tissue manifested by cardiac fibroblasts in a process called fibrosis. Cardiac muscle scarring leads to its
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Although it is not related to the stem cell field, thought it might interest this community. It deals about cardiac fibroblasts role in development and in pathology.

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British courier has 42 hours to get life-saving stem cells home

British courier has 42 hours to get life-saving stem cells home | Stem Cells & Tissue Engineering | Scoop.it
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When Peter Hodes was caught in a hurricane in Washington with no flights, staff moved heaven and earth to get him back to Britain.

The volunteer stem cell carrier travels light and fast because once harvested these life-saving cells, which can prove vital for leukaemia patients, only survive a maximum of 72 hours outside a body.

Hodes' carries the cells in an icebox, which lasts 42 hours.



Read more: http://www.nydailynews.com/life-style/health/british-courier-42-hours-life-saving-stem-cells-home-article-1.1773841#ixzz30PHAn7B5

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