Stem Cells & Tissue Engineering
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Stem Cells & Tissue Engineering
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Generation of renal progenitor cells from human embryonic stem cells - Differentiation protocol - LifeMap Discovery

Generation of renal progenitor cells from human embryonic stem cells - Differentiation protocol - LifeMap Discovery | Stem Cells & Tissue Engineering | Scoop.it
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Stem cell researchers, this is the ultimate protocol tool for you!

- View the protocol flow, time, and growth factors

- Explore the gene expression of the differentiated cells

- Learn about developmental signals which govern the                  differentiation process

 

See our huge protocol collection: 

http://discovery.lifemapsc.com/stem-cell-differentiation/protocols

 

 

 

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From pluripotent stem cells to kidneys in a dish

From pluripotent stem cells to kidneys in a dish | Stem Cells & Tissue Engineering | Scoop.it

http://discovery.lifemapsc.com/in-vivo-development/kidney

Jacob Blumenthal's insight:

Two new papers, published in Cell Stem Cell, and Nature Cell Biology magazines, describes protocols for generation of kidney structures from human pluripotent stem cells.

http://www.nature.com/ncb/journal/vaop/ncurrent/full/ncb2894.html

http://www.cell.com/cell-stem-cell/abstract/S1934-5909(13)00501-8

 

To learn about the embryonic development, anatomical compartments, gene expression of the kidney and related stem cell differentiation protocols:

http://discovery.lifemapsc.com/in-vivo-development/kidney

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Anthony Atala: Printing a human kidney | Video on TED.com

Surgeon Anthony Atala demonstrates an early-stage experiment that could someday solve the organ-donor problem: a 3D printer that uses living cells to output a transplantable kidney. Using similar technology, Dr.
Jacob Blumenthal's insight:

If you are interested in tissue engineering, regenerative medicine, and bioprinting...this is definitely a MUST SEE presentation!!

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Building a Kidney: Using Pluripotent Stem Cells to Differentiate Kidney Structures

Building a Kidney:  Using Pluripotent Stem Cells to Differentiate Kidney Structures | Stem Cells & Tissue Engineering | Scoop.it
Jacob Blumenthal's insight:

Kidneys develop from the intermediate metanephros (IM), which gives rise to the metanephric mesenchyme (MM) and the ureteric bud (UB). The MM forms the glomerulus and the renal tubules while the UB differentiates into the collecting duct. Reciprocal interactions between the MM and the UB are necessary for development of the kidney. Both the MM and the UB contain stem cells, however, once these cells are removed from their respective niches, they spontaneously terminally differentiate, rendering, creation of kidney structures in vitro very difficult. Recently, two papers (from Nishinakamura and Little's research groups) describe the use ... (Read the full story in the newsletter).

http://us4.campaign-archive1.com/?u=985051700e9649000fa0c0d4a&id=22f09f7211&e=f1b990f7f8

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'Mini-kidney' structures generated from human stem cells for first time

'Mini-kidney' structures generated from human stem cells for first time | Stem Cells & Tissue Engineering | Scoop.it
Jacob Blumenthal's insight:

Researchers from the Salk institute have generated three-dimensional kidney structures from human induced pluripotent stem cells, as a platform to study the development and diseases of the kidney. 

http://www.nature.com/ncb/journal/vaop/ncurrent/pdf/ncb2872.pdf#figures

 

To learn about the embryonic developement of the kidney, and related stem cells differentiation protocols:

http://discovery.lifemapsc.com/in-vivo-development/kidney

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