Social Neuroscien...
Follow
Find tag "Alzheimer's"
3.7K views | +0 today
Social Neuroscience Advances
Understanding ourselves and how we interact
Your new post is loading...
Your new post is loading...
Rescooped by Jocelyn Stoller from the plastic brain
Scoop.it!

Why People with Down Syndrome Invariably Develop Alzheimer's Disease

Why People with Down Syndrome Invariably Develop Alzheimer's Disease | Social Neuroscience Advances | Scoop.it

Amyloid plaques are found in the brains of people with Down syndrome and Alzheimer’s disease. Credit Juan Gartner.

 

Study reveals how the SNX27 protein regulates the generation of beta amyloid.

 

A new study by researchers at Sanford-Burnham Medical Research Institute reveals the process that leads to changes in the brains of individuals with Down syndrome—the same changes that cause dementia in Alzheimer’s patients. The findings, published in Cell Reports, have important implications for the development of treatments that can prevent damage in neuronal connectivity and brain function in Down syndrome and other neurodevelopmental and neurodegenerative conditions, including Alzheimer’s disease.

 

Down syndrome is characterized by an extra copy of chromosome 21 and is the most common chromosome abnormality in humans. It occurs in about one per 700 babies in the United States, and is associated with a mild to moderate intellectual disability. Down syndrome is also associated with an increased risk of developing Alzheimer’s disease. By the age of 40, nearly 100 percent of all individuals with Down syndrome develop the changes in the brain associated with Alzheimer’s disease, and approximately 25 percent of people with Down syndrome show signs of Alzheimer’s-type dementia by the age of 35, and 75 percent by age 65. As the life expectancy for people with Down syndrome has increased dramatically in recent years—from 25 in 1983 to 60 today—research aimed to understand the cause of conditions that affect their quality of life are essential.


Via iPamba
more...
No comment yet.
Rescooped by Jocelyn Stoller from the plastic brain
Scoop.it!

Magnetic brain stimulation treatment shown to boost memory

Magnetic brain stimulation treatment shown to boost memory | Social Neuroscience Advances | Scoop.it
Non-invasive transcranial technique leads to 24-hour-long improvement in memory function and could lead to new treatments for Alzheimer's and other conditions

Via iPamba
more...
No comment yet.
Rescooped by Jocelyn Stoller from the plastic brain
Scoop.it!

Antidepressant May Slow Alzheimer’s Disease

Antidepressant May Slow Alzheimer’s Disease | Social Neuroscience Advances | Scoop.it
A commonly prescribed antidepressant can reduce production of the main ingredient in Alzheimer’s brain plaques, according to new research at Washington University School of Medicine in St. Louis and the University of Pennsylvania.

Via iPamba
more...
No comment yet.
Rescooped by Jocelyn Stoller from the plastic brain
Scoop.it!

Long term use of benzodiazepine for anxiety & sleep disorders can increase risk of Alzheimer’s disease

Long term use of benzodiazepine for anxiety & sleep disorders can increase risk of Alzheimer’s disease | Social Neuroscience Advances | Scoop.it

This case-control study based on 8980 individuals representative of elderly people living in the community in Quebec showed that the risk of Alzheimer’s disease was increased by 43-51% among those who had used benzodiazepines in the past. Risk increased with density of exposure and when long acting benzodiazepines were used. Further adjustment on symptoms thought to be potential prodromes for dementia—such as depression, anxiety, or sleep disorders—did not meaningfully alter the results.


Via iPamba
more...
No comment yet.
Rescooped by Jocelyn Stoller from the plastic brain
Scoop.it!

Analysis of African Plant Reveals Possible Treatment for Aging Brain

Analysis of African Plant Reveals Possible Treatment for Aging Brain | Social Neuroscience Advances | Scoop.it
Salk scientists find that a plant used for centuries by healers of São Tomé e Príncipe holds lessons for modern medicine.

Via iPamba
more...
No comment yet.
Rescooped by Jocelyn Stoller from the plastic brain
Scoop.it!

Antidepressant Holds Promise in Treating Alzheimer's Agitation - 02/18/2014

The antidepressant drug citalopram, sold under the brand names Celexa and Cipramil and also available as a generic medication, significantly relieved agitation in a group of patients with Alzheimer's disease. In lower doses than those tested, the drug might be safer than antipsychotic drugs currently used to treat the condition, according to results of a clinical trial led by Johns Hopkins researchers that included seven other academic medical centers in the United States and Canada.

Via iPamba
more...
No comment yet.