Senior Research Project: Alzheimer's Disease
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Alzheimer's Disease Now Fastest-Growing Threat To US Health, Report Finds - Huffington Post

Alzheimer's Disease Now Fastest-Growing Threat To US Health, Report Finds - Huffington Post | Senior Research Project: Alzheimer's Disease | Scoop.it
Moneycontrol.com Alzheimer's Disease Now Fastest-Growing Threat To US Health, Report Finds Huffington Post SEATTLE, March 6 (Reuters) - Alzheimer's disease is the fastest-growing threat to Americans' health, while early childhood illnesses and...
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Its scary to think that this disease is growing so largely as a threat to this country. Especially when it may also be genetic & my grandmother is suffering from Alzheimer's for about 20 years now. I'm confused though as to why poor counties are less suseptible to diseases like Alzheimer's. I understand that since they can't afford things like alcohol they may be less likely to get caught up in those bad lifestyles, and I understand that rape isnt take as seriously by thier governments therefore leading to more HIV and AIDs. Could this be telling us something about Alzhiemer's ? Maybe it has to do with our lifestyle choices and the things we are exposed to in this country.....

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Wales has lowest diagnosis rates for dementia

Wales has lowest diagnosis rates for dementia | Senior Research Project: Alzheimer's Disease | Scoop.it
old age care Wales has the lowest diagnosis rates for dementia compared to the rest of the UK, according to new figures released by a leading charity. Statistics from the Alzheimer's Society show that just 38.5% of sufferers in Wales received a ...
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How to Survive as an Alzheimer’s Caregiver: The Single Most Important Thing You Can Do | Alzheimer's Reading Room

How to Survive as an Alzheimer’s Caregiver: The Single Most Important Thing You Can Do | Alzheimer's Reading Room | Senior Research Project: Alzheimer's Disease | Scoop.it

Let’s face it. If you’re a caregiver for someone with Alzheimer’s disease you’re carrying around a ton of stress.

 

Sleepless nights, physical exhaustion, irritability, feeling overwhelmed by your seemingly endless list of duties. These are just a few of the signs that your solemn responsibility is getting the best of you.

 

You can find plentiful advice on the Internet about how to deal with all this stress. Some sites tell you to join a support group. Great. If only you had time to attend the meetings. The same goes for the commonly given advice to go out to a movie. That’s fine but do you have someone to take care of your loved one while you’re out?


Via Becky B
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Christina Mediate's comment, March 7, 2013 12:31 PM
This article describes how stressed carefivers are & how they never have time to unwind. Asking for help is the best thing a caregiver can do! My grandfather's health was effects negritively due to always having to take care of my grandmother who has Alzheimer's. His doctor told him to only visit her at the nursing home 3 days a week for the full day, instead of seven. The other day the nurses or my father will tend tend to her. My mother will often make him a plate of leftovers so that he won't have to cook & she goes up to his house to clean as well. We do as much as we can to help my grandparents, but it wasn't easy getting my grandfather to "take a break". But just because they don't ask for help, doesn't mean they don't need/want it
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Alzheimer's Disease, Types of Dementia, and What is the Difference Between Alzheimer's and Dementia | Alzheimer's Reading Room

Alzheimer's Disease, Types of Dementia, and What is the Difference Between Alzheimer's and Dementia | Alzheimer's Reading Room | Senior Research Project: Alzheimer's Disease | Scoop.it
Dementia is a symptom, and Alzheimer's disease is the cause of the symptom.

Via Helene Cohen
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Pro-life vid of day: Husband's devotion to wife with Alzheimer's

Pro-life vid of day: Husband's devotion to wife with Alzheimer's | Senior Research Project: Alzheimer's Disease | Scoop.it
Bill epitomizes devotion and sacrifice as he cares daily for the needs of his bride Glad (diagnosed with Alzheimer's), whom he wed over 50 years ago.
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Christina Mediate's comment, February 21, 2013 12:42 PM
This video is sad but true. When a person is diagnosed with the terrible disease of Alzheimer's, there comes a point where they literally can't do the simplest things for them self. In this video you see the husband helping his wife drink, brush her hair, & put her earrings in. Just simple daily activities. This video made me tear up because my grandfather has devoted the last 20 yrs of his marriage to taking care of my grandmother who has Alzheimer's. She stays at a nursing home but he goes to see her all day everyday. He talks to her & feeds her. He cares for her in every possible, just like the couple in this video.
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Promising compound restores memory loss and reverses symptoms of Alzheimer’s Disease

Promising compound restores memory loss and reverses symptoms of Alzheimer’s Disease | Senior Research Project: Alzheimer's Disease | Scoop.it

New research in the FASEB Journal by NIH scientists suggests that a small molecule called TFP5 rescues plaques and tangles by blocking an overactive brain signal, thereby restoring memory in mice with Alzheimer’s — without obvious toxic side effects.

 

“We hope that clinical trial studies in AD patients yield an extended and a better quality of life, as observed in mice upon TFP5 treatment,” said Harish C. Pant, Ph.D., a senior researcher involved in the work from the Laboratory of Neurochemistry at the National Institute of Neurological Disorders at Stroke at the National Institutes of Health.

 

“We suggest that TFP5 should be an effective therapeutic compound.”

To make this discovery, Pant and colleagues used mice with a disease considered the equivalent of Alzheimer’s. One set of these mice were injected with the small molecule TFP5, while the other was injected with saline as placebo. The mice, after a series of intraperitoneal injections of TFP5, displayed a substantial reduction in the various disease symptoms along with restoration of memory loss.

 

In addition, the mice receiving TFP5 injections experienced no weight loss, neurological stress (anxiety) or signs of toxicity. The disease in the placebo mice, however, progressed normally as expected.

 

TFP5 was derived from the regulator of a key brain enzyme, called Cdk5. Over-activation of Cdk5 is implicated in the formation of plaques and tangles, the major hallmark of Alzheimer’s disease.


Via Dr. Stefan Gruenwald
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pdeppisch's comment, January 8, 2013 3:40 PM
That would be nice as both my parents died from Alzheimer's as best I could tell.
Audrey's comment, January 8, 2013 5:20 PM
If this is true, then it would be fantastic.
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Alzheimer's to triple by 2050 as baby boomers age

The number of U.S. residents aged 65 and older living with Alzheimer's disease is expected to nearly triple to 13.8 million by 2050 as aging baby boomers swell the ranks of those living with the brain-wasting disease, U.S. researchers said on Wednesday.

 

 


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Greg Wurn's comment, February 8, 2013 1:40 PM
one of the reason they are feeding flouride to the population, kill them with cancer before they get Alzhimers
Christina Mediate's comment, February 24, 2013 5:13 PM
I've read that there was hope to have a cure for Alzheimer's by 2025 several times throughout my research. However, this article is saying that the efforts of the Obama Administration to help find this cure, could be unsuccessful due to cutting costs. It's already to late for my grandmother seeing as how she has been living with this disease for about 15 years and is now 86 years old.
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Treatment to prevent Alzheimer’s disease moves a step closer | KurzweilAI

A new drug designed to prevent the early stages of Alzheimer’s disease could enter clinical trials in a few years’  time, according to scientists.

Alzheimer’s disease begins when a protein called amyloid-β (Aβ) starts to clump together in senile plaques in the brain, damaging nerve cells and leading to memory loss and confusion.

 

 


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Christina Mediate's comment, February 24, 2013 5:56 PM
Being able to stop the formation of senile plaques makes this drug look promising. Those plaques are what cause the damage to the brain cells and start the initial memory loss. I'm anxious to see how it works on humans though. Right now it's only safe on the mice. But this is a very crucial step towards a possible new treatment or cure for the disease.
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Confessions Of A Worn-Out Alzheimer's Caregiver

Confessions Of A Worn-Out Alzheimer's Caregiver | Senior Research Project: Alzheimer's Disease | Scoop.it
I was a caregiver for seven long years for Dr. Edward Theodoru, my beloved Romanian soul mate of 30 years. In the early and mid-stages of his dementia I did many things I was later not proud of. At all.
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Christina Mediate's comment, February 24, 2013 6:01 PM
My grandmother used to make "stupid" mistakes when she started forgetting things. My pap would argue with her about things such as hiding stuff in the house. She would claim it wasnt her but he would argue anyway. This was before he realized that something, was wrong. Once she was diagnosed with the disease, we had caregivers come to their home to help out. My grandmother would get violent and hit them. She'd even hit my mother and my brother and I. At the time, i was only a few years old. Caregiving is a tough job,but its even more stressful and sad when you are caring for someone you love. Seeing the changes is hard to deal with. Its best to follow in this woman's footsteps, and avoid arguements, but rather redirect the conversations and be understanding
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Vitamin D Fights Depression and Alzheimer’s Disease

Vitamin D Fights Depression and Alzheimer’s Disease | Senior Research Project: Alzheimer's Disease | Scoop.it
Study reveals that getting enough sunlight exposure for healthy Vitamin D levels could be the super-simple remedy for depression and Alzheimer's.

Via Richard Drake
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Historical Review of PET Imaging for Alzheimer's and Parkinson's ...

Historical Review of PET Imaging for Alzheimer's and Parkinson's Disease in Neurology. Posted on March 5, 2013 by lrnlab. The history of cerebral PET scanning: From physiology to cutting-edge technology.
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What Is Alzheimer's Disease?

These very-short "pocket" films are designed to be viewed anywhere at anytime: a doctor's office, a Congressional hallway, a family living room. Please take ...
Christina Mediate's insight:

This is a great video. It really pin points the main aspects of the disease. With the experience I've gone though with this disease in my grandmother, I can definitely relate to the  information given in this video. It mentions how the three stages occur. My grandmother is in the third and final stage, which at this point in time, will eventually & unfortunately result in death. 

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Sandy Spencer's comment, September 1, 2013 7:15 PM
I agree, this is a great video, I've shared it many times as well. http://bit.ly/alzheimers-support
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Blood vessel damage found in brains of people with Alzheimer's

Blood vessel damage found in brains of people with Alzheimer's | Senior Research Project: Alzheimer's Disease | Scoop.it
Researchers compared the brains of people with and without Alzheimer's disease and found that those with Alzheimer's had greater areas of blood vessel damage than those without the condition.
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Comfort Clothing for someone with Alzheimer’s, Dementia or Memory Loss

Comfort Clothing for someone with Alzheimer’s, Dementia or Memory Loss | Senior Research Project: Alzheimer's Disease | Scoop.it
When choosing clothes for my Mom I tried to think “comfort” first– and then “practicality.” In early stages of Dementia, she chose her own wardrobe but in later stages...

Via Registered Nursing Home Manager
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Christina Mediate's comment, February 24, 2013 5:07 PM
Comfort is especially important in my grandmother's case. Since she can not walk, she spends her days in the nursing home either laying in bed or curled up in a wheelchair. When in her wheelchair, she is kind of hunched over & her hands are always curled up to her chest. Since she hasn't used a lot of her joints in about 20 years, she's very stiff. We always buy her XL sweat pants and sweatshirts. Not being active has made her gain lots of weight over the years.
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Why exercise slows memory loss in Alzheimer’s

Why exercise slows memory loss in Alzheimer’s | Senior Research Project: Alzheimer's Disease | Scoop.it
A stress hormone produced during moderate exercise may protect the brain from memory changes related to Alzheimer’s disease

Via Dimitris Agorastos
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Natalie Stewart's curator insight, January 28, 2013 3:46 PM

A research team, led by Marie-Christine Pardon in the School of Biomedical Sciences, discovered that the stress hormone CRF—or corticotrophin-releasing factor—may have a protective effect on the brain from the memory changes brought on by Alzheimer’s disease.
CRF is most associated with producing stress and is found in high levels in people experiencing some forms of anxiety and depressive diseases. Normal levels of CRF, however, are beneficial to the brain, keeping the mental faculties sharp and aiding the survival of nerve cells.
 

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One step closer to Alzheimer's disease prevention | Machines Like Us

One step closer to Alzheimer's disease prevention | Machines Like Us | Senior Research Project: Alzheimer's Disease | Scoop.it
A new drug to prevent the early stages of Alzheimer's disease could enter clinical trials in a few years' time according to scientists.

Via LeapMind
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Synaptic molecule works differently than thought; may mean new targets for Alzheimer's

Synaptic molecule works differently than thought; may mean new targets for Alzheimer's | Senior Research Project: Alzheimer's Disease | Scoop.it
Researchers have upended a long-held view about the basic functioning of a key receptor molecule involved in signaling between neurons, and describe how a compound linked to Alzheimer’s disease impacts that receptor and weakens synaptic connections...

Via Dimitris Agorastos
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Memory Loss May Not Be Only Sign of Early Alzheimer's - Dementia Today

Memory Loss May Not Be Only Sign of Early Alzheimer's - Dementia Today | Senior Research Project: Alzheimer's Disease | Scoop.it
Early Alzheimer's (RT @DementiaToday: Memory Loss May Not Be Only Sign of Early Alzheimer's http://t.co/9xRwLLYz #dementia, #alz)
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