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EMBO 2012 - International workshop on Evolution in the Time of Genomics

EMBO 2012 - International workshop on Evolution in the Time of Genomics | Science-Videos | Scoop.it

Molecular evolution was born fifty years before the planned Conference, with a seminal paper by Zuckerkandl and Pauling (1962) which demonstrated that aminoacid changes in the globins followed a molecular clock and could provide information on the phylogeny of vertebrates and on the timing of their appearance on earth.

Principal themes and objectives of the event From changes in aminoacids to changes in nucleotides, the molecular level has provided an essential input into evolutionary investigations for the past decades. More recently, the molecular level has moved from the genes to the genome, so far mainly in the case of vertebrates (in which the coding sequences only represent about 2% of the total). The availability of full genome sequences has provided new possibilities for investigators in the field and major problems can now be tackled in a very precise way using bioinformatic tools. Indeed, an example of this approach has been the recent solution (Bernardi, 2007)of a twenty-year-old debate, that between neutralists and selectionists.
One of the major current debates concerns adaptive vs. non-adaptive evolution. Random events in evolution were originally raised as a fundamental problem by Jacques Monod in his famous book "Chance and necessity". The problem has now been shifted to the genome level. A preliminary discussion took place in October 2010 in a Meeting "Chance and Necessity in Evolution" (Ravello, Italy; papers are in press in a special issue of Genome Biology and Evolution). The proposed meeting should go deeper into such a basic issue. While this will be one of the main subject of the meeting in which different views will confront each other (with Bernardi, Jarosz, Koonin, Ohta, Ptashne), other basic topics in Genome Evolution will be addressed. Werner Arber, Hamilton Smith (two Nobel Laureates) and George Church will discuss in depth the results obtained so far "directing" evolution in microbial systems, their interpretation and even the ethical issues raised. Davidson, Gehring and Gojobori will deal with the evolution of developmental processes; Martin, Saccone and Wallace with the evolution of mitochondrial genomes; Okada and Shapiro with the impact of mobile elements on genome evolution; Jeffreys and Saitou with recombination and biased gene conversion; Bustamante, Felsenfeld, Hartl and Haussler with regulation of gene expression and copy number variation in the human genome. Last but not least, Emile Zuckerkandl will recollect the beginning of Molecular Evolution.


7 — 9 May 2012 | Venice, Italy
Istituto Veneto di Scienze, Lettere ed Arti
Palazzo Franchetti

 

http://events.embo.org/12-evolution/

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Genetics in Mendelian Human Disease - Broad Institute (2012)

The Primer on Medical and Population Genetics is a series of informal weekly discussions of basic genetics topics that relate to human populations and disease.

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Dan Roden: "Genomes, Hype, and a Realistic Pathway to Personalized Medicine

A talk by Dr. Dan Roden: "Genomes, Hype, and a Realistic Pathway to Personalized Medicine"
Roden is widely-recognized for his expertise in clinical, genetic, cellular, and molecular basis of arrhythmia susceptibility and variability responses to arrhythmia therapies. Over the past decade, he has led Vanderbilt's broader efforts in pharmacogenomics discovery and implementation. Currently, he directs the Vanderbilt DNA databank, BioVU and the John A. Oates Institute for Experimental Therapeutics. Roden also serves as Principal Investigator for the Vanderbilt sites of the National Institutes of Health's Pharmacogenomics Research Network and the National Human Genome Research Institute's Electronic Medical Records and Genomics network.

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GenomeTV - Full featured lectures and meeting videos about Genomics and Genome Annotation

GenomeTV - Full featured lectures and meeting videos about Genomics and Genome Annotation | Science-Videos | Scoop.it

The Genomics in Medicine Lecture Series is sponsored by NHGRI, in collaboration with Suburban Hospital and Johns Hopkins. Each lecture takes place at Suburban Hospital's lower level auditorium at 8600 Old Georgetown Road in Bethesda, Md. All are welcome to the hour-long lectures, which begin at 8 a.m. on the first Friday of the month, from December 2011 through June 2012.

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DOE JGI Genomics of Energy & Environment Meeting (2012) - 20 VIDEO Lectures

7th Annual DOE JGI Genomics of Energy & Environment Meeting on March 20, 2012 in Walnut Creek, California.

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Cancers Genomes and their Implications for Curing Cancer (by Bert Vogelstein, JHU)

The full lecture title is "Cancers - Their Genomes, Microenvironments, and Susceptibility to Bacteria-based Therapies" by Bert Vogelstein. The Johns Hopkins Center for Biotechnology Education and the Department of Biology in the Krieger School of Arts and Sciences hosted the American Society for Microbiology's Conference for Undergraduate Educators (ASMCUE) on the Homewood campus. Bert Vogelstein gave the closing plenary lecture, "Cancers - Their Genomes, Microenvironments, and Susceptibility to Bacteria-based Therapies". He teaches at John Hopkins University.

ASMCUE, now in its 18th year, is a professional development conference for approximately 300 educators. Each year, its steering committee organizes a program that offers access to premier scientists in diverse specialties and to educators leading biology education reform efforts. For more information on the conference, go to http://www.asmcue.org/page02d.shtml

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The Genetic Age - The Era of Personalized Medicine (Northwestern University) [Panel Discussion]

The Era of Personalized Medicine is a forward-looking discussion focusing on the opportunities and challenges facing scientists, healthcare providers, policy makers, and society as we enter the era of personalized medicine. This event was sponsored by Northwestern University's Center for Genetic Medicine.

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Genomics and Personalized Medicine - Get yourself sequenced

Michael Snyder, Professor of Genetics and Chair of the Department of Genetics at Stanford, discusses advances in gene sequencing, the impact of genomics on medicine, the potential for personalized medicine. and efforts at Stanford to further study these issues.

 

Many more genomics lectures: http://tinyurl.com/7osb3ss

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Biomedical Science and Molecular Genetics Lecture (BM-2002M)

Lectures delivered as part of the Biomedical Science (Hons) degree programme at the University of Bradford.

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