An unexpected interaction between neurotransmitter systems may explain psychosis and hallucinations, according to a fascinating new paper.
Serotonin (5HT) and glutamate are two neurotransmitters. Up until now, it was thought that they acted independently. A given neuron might have receptors for both serotonin and glutamate, but they didn't interact: serotonin would never affect the glutamate receptors, and vice versa.
The new research overturns that view. Authors Miguel Fribourg and colleagues of Mount Sinai School of Medicine show, in a series of elegant experiments in mice, that different receptors can cluster together, forming a complex. The two receptors, serotonin's 5HT2A and glutamate's mGluR2, can talk to each other.
However, this doesn't seem to happen under normal conditions. Serotonin and glutamate don't seem to trigger the receptor interaction, or at least not very much. Only certain drugs can do it. And this is where it gets really interesting.
An economic analysis of the 2007-08 price spike In the article the authors, Harald von Witzke and Steffen Noleppa, analyze the determinants of the 2007-08 price spike and quantify the impact of a number of supply and demand side variables on monthly prices of wheat, corn and soybeans. The results of their analysis suggest that the price spike of 2007-08 can largely be explained by changes in supply and demand determining variables, leaving little room for unexplained price changes that might be attributed to speculation.
Mit den neuesten Zahlen zum Kohlendioxid-Ausstoß haben wir es ja nun amtlich, dass der Versuch einer präventiven Klimapolitik gescheitert ist. Der Mensch verändert die Atmosphäre unkontrolliert und wird es auch in Zukunft weiter tun. Jetzt reden alle von Anpassung an den Klimawandel.
Ich kann das allgemeine Aufatmen quasi hören. Anpassen an den Klimawandel, das sind ein paar höhere Deiche und so, und wir haben ja noch Zeit. Schließlich beziehen sich die ganzen unerfreulichen Vorhersagen auf etwa das Jahr 2100. Unsere ungeborenen Enkel, die schaffen das schon. Bis dahin, her mit den Schokomandeln..
Calling all sci-fi fans! On Wednesday night at 10pm ET/PT, Science debuts Prophets of Science Fiction, a series that explores the relationship between science fiction and the constantly-evolving worlds of science and technology. Executive Producer Ridley Scott, the creative genius behind Hollywood classics including Alien, Blade Runner and Gladiatorand a student of science fiction explores how the dreams of storytellers like Jules Verne, Isaac Asimov, George Lucas and Phillip K. Dick often become the inspiration for researchers seeking mankind’s next transformative discovery.The premiere episode looks at the world and mind of Mary Shelley, who is widely credited with creating the science fiction genre. Her seminal work, Frankenstein, provided a springboard for the future study and development of organ transplantation, cardiac defibrillation, electric batteries and many other modern advances.
This Stanford Continuing Studies course is the second of a six-quarter sequence of classes exploring the essential theoretical foundations of modern physics. The topics covered in this course focus on quantum mechanics. The course is taught by Leonard Susskind, the Felix Bloch Professor of Physics at Stanford University...
For his novel approach to creating maps that enable researchers to zoom in on the human genome and reveal features of DNA structure inside the nucleus, Erez Lieberman Aiden has been named the 2011 Grand Prize winner for the GE & Science Prize for Young Life Scientists. The annual competition includes a grand prize award of $25,000 and is supported by GE Healthcare and the journal Science.
How does the 2-meter long human genome fold up inside the nucleus of a cell? Aiden, a fellow at the Harvard Society of Fellows and visiting faculty at Google, developed a method for three-dimensional genome sequencing that seems to answer this question. He and his team pioneered the technique, known as Hi-C, and deployed it to create “the first genome-wide spatial map of the human genome,” he explained.
A startup in British Columbia is making a long-shot wager that it can build a machine that generates electricity through nuclear fusion — the same process that powers the sun. The scientist behind the machine calls it an "insanely ambitious" project.
The submission period for The Open Laboratory 2011 has now ended. We have 717 entries this year and they all look great (all listed below)! This list alone, even though only 52 of them will make it into the book, is quite a snapshot of the year in science blogging and quite a resource – share it with your friends to show them the quality and beauty of science on the Web.
Quantum Diaries is a Web site that follows physicists from around the world as they experience life at the energy, intensity and cosmic frontiers of particle physics. Through their bios, videos, photos and blogs, the diarists offer a personal look at the daily lives of particle physicists.