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Salus (Health)
P4 (predictive, preventive, personalized, partecipatory) medicine
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20 Predictions in Medicine And Healthcare for 2014

20 Predictions in Medicine And Healthcare for 2014 | Salus (Health) | Scoop.it

Every January, I publish my predictions for the upcoming year regarding medicine and healthcare. Usually, the majority of these predictions turn out to be valid later on, although I prefer calling them apparent trends rather than actual predictions.


Here are my 20 points for 2014.

1) Google Glass to be used in everyday healthcare
2) IBM Watson’s first commercial use by hospitals
3) Direct-to-consumer genomics to get new rules
4) 3D printing artificial limbs and biomaterials goes mainstream
5) The healthcare experience will be brought to the home
6) LEGO Mindstorms to be applied for DIY biotech
7) Home diagnostics to be the key trend
8) Wearable MRI technology
9) Optogenetics to be featured at major scientific journals
10) Bigger role of MOOCs as medical schools change approach about digital literacy
11) More connected digital healthcare devices and services
12) The first steps of Google Calico to be public
13) EEG controlled devices to appear
14) Exoskeletons will be featured worldwide
15) First really useful food scanners to be released
16) Gamifying the healthy lifestyle
17) Finally remote touch and simpler data input become possible
18) Nanotechnology to be included in the medical curriculum
19) Decision on newborn genome sequencing to be made
20) First results of Ray Kurzweil’s work at Google to be revealed


Read more: http://scienceroll.com/2014/01/03/2014-predictions/


Via Parag Vora
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Personalized cancer medicine: molecular diagnostics, predictive biomarkers, and drug resistance. [Clin Pharmacol Ther. 2013] - PubMed - NCBI

Personalized cancer medicine: molecular diagnostics, predictive biomarkers, and drug resistance. [Clin Pharmacol Ther. 2013] - PubMed - NCBI | Salus (Health) | Scoop.it

Abstract

The progressive elucidation of the molecular pathogenesis of cancer has fueled the rational development of targeted drugs for patient populations stratified by genetic characteristics. Here we discuss general challenges relating to molecular diagnostics and describe predictive biomarkers forpersonalized cancer medicine. We also highlight resistance mechanisms for epidermal growth factor receptor (EGFR) kinase inhibitors in lung cancer. We envisage a future requiring the use of longitudinal genome sequencing and other omics technologies alongside combinatorial treatment to overcome cellular and molecular heterogeneity and prevent resistance caused by clonal evolution.

Pasquale Valente's insight:

"The solution to the inevitable challenge of polygenic cancer drug resistance is to identify not only all exploitable molecular abnormalities but also the full range of resistance mechanisms and there after to employ precision combinatorial targeted therapy matched specifically to the fully defined tumor profile"

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Personalized Medicine: The Future is Now | FDA Voice

Personalized Medicine: The Future is Now | FDA Voice | Salus (Health) | Scoop.it
"We now know that patients with similar symptoms may have different diseases with different causes. Individual patients who may appear to have the same disease may respond differently (or not at all) to treatments of that disease.FDA has been playing a critical role in the growth of this new era for a number of years."
Pasquale Valente's insight:
- See more at: http://www.fda.gov/downloads/ScienceResearch/SpecialTopics/PersonalizedMedicine/UCM372421.pdf
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Personalized Medicine and Health Economics: Is Small the New Big? A White Paper

Personalized Medicine and Health Economics: Is Small the New Big? A White Paper | Salus (Health) | Scoop.it

This White Paper is based on an International Workshop (Personalized Medicine: The future is already here but are we ready for it?”) that was held at the Dead Sea in Israel on 5–6 September 2012.

Pasquale Valente's insight:

Raju Kucherlapati  “Implementation of personalized medicine is going to result in better outcomes for patients, and I truly believe there is going to be reduced cost. It’s happening today, it’s not some time in the future. This is going to be the normal practice as we move forward.”

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