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P4 (predictive, preventive, personalized, partecipatory) medicine
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Rescooped by Pasquale Valente from Longevity science
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ATHENA "desktop human" for drug and toxic agent screening gets a liver

ATHENA "desktop human" for drug and toxic agent screening gets a liver | Salus (Health) | Scoop.it

A five-year, US$19 million multi-institutional effort is working on developing a "desktop human" that could reduce the need for animal testing in the development of new drugs. The "homo minitus" is a drug and toxicity analysis system that would comprise four human organ constructs interconnected to mimic the response of human organs. The project has now reported success in the development of its first organ construct, a human liver construct that responds to exposure to a toxic chemical much like a real liver.

 

 


Via Ray and Terry's
Pasquale Valente's insight:

the ultimate goal of the project is to, "build a lung that breathes, a heart that pumps, a liver that metabolizes and a kidney that excretes."

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Pills of the future: nanoparticles - MIT News Office

Pills of the future: nanoparticles - MIT News Office | Salus (Health) | Scoop.it
Researchers design drug-carrying nanoparticles that can be taken orally
Pasquale Valente's insight:

"In this study, the researchers demonstrated oral delivery of insulin in mice. Nanoparticles coated with Fc proteins reached the bloodstream 11-fold more efficiently than equivalent nanoparticles without the coating."

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