Rotavirus
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Distribution of rotavirus strains and strain-specific effectiveness of the rotavirus vaccine after its introduction: a systematic review and meta-analysis

Distribution of rotavirus strains and strain-specific effectiveness of the rotavirus vaccine after its introduction: a systematic review and meta-analysis | Rotavirus | Scoop.it
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VIP, Very Important Paper

 

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Childhood Vaccines Again Deemed Generally Safe

Stream WZTV Fox 17 Newscasts LIVE starting with Fox 17 This Morning at 5am and News at 9pm. NEW YORK (AP) -- The latest analysis of childhood vaccines confir...
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A Fox news video on vaccine safety

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Toutes les tailles | The Potential of Vaccines Against Rotavirus | Flickr : partage de photos !

Toutes les tailles | The Potential of Vaccines Against Rotavirus | Flickr : partage de photos ! | Rotavirus | Scoop.it
Flickr est certainement le meilleur service de gestion et de partage de photos en ligne au monde. Exposez vos photos préférées au monde entier. Partagez, en toute sécurité et en toute confidentialité, vos photos à vos amis et à votre famille. Et publiez les photos de votre mobile sur un blog.
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Do you see anything wrong with this infographics....

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ASMscience | Rotavirus

Rotaviruses (RV) are ubiquitous, highly infectious, segmented double-stranded RNA genome viruses of importance in public health because of the severe acute gastroenteritis they cause in young children and many animal species. They are very well adapted to their host, with symptomatic and asymptomatic reinfections being virtually universal during the first 3 years of life. Antibodies are the major arm of the immune system responsible for protecting infants from RV reinfection. The relationship between the virus and the B cells (Bc) that produce these antibodies is complex and incompletely understood: most blood-circulating Bc that express RV-specific immunoglobulin (Ig) on their surface (RV-Ig) are naive Bc and recognize the intermediate capsid viral protein VP6 with low affinity. When compared to non-antigen-specific Bc, RV-Bc are enriched in CD27+ memory Bc (mBc) that express IgM. The Ig genes used by naive RV-Bc are different than those expressed by RV-mBc, suggesting that the latter do not primarily develop from the former. Although RV predominantly infects mature villus enterocytes, an acute systemic viremia also occurs and RV-Bc can be thought of as belonging to either the intestinal or systemic immune compartments. Serotype-specific or heterotypic RV antibodies appear to mediate protection by multiple mechanisms, including intracellular and extracellular homotypic and heterotypic neutralization. Passive administration of RV-Ig can be used either prophylactically or therapeutically. A better understanding of the Bc response generated against RV will improve our capacity to identify improved correlates of protection for RV vaccines.
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A good overview of Rotavirus

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