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RNAi
RNA-interference is an RNA-dependent sequence-specific gene silencing process initiated by dsRNA
Curated by Subhas Hajeri
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RNA Interference (RNAi) Induced Gene Silencing: A Promising Approach of Hi-Tech Plant Breeding

RNA Interference (RNAi) Induced Gene Silencing: A Promising Approach of Hi-Tech Plant Breeding | RNAi | Scoop.it
RNA Interference (RNAi) Induced Gene Silencing: A Promising Approach of Hi-Tech Plant Breeding: RNA interferen... http://t.co/wfDGbsuG3Z
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Watch now: NOVA | RNAi Explained | WCVE PBS Video

Watch now: NOVA | RNAi Explained | WCVE PBS Video | RNAi | Scoop.it
An immune response recently discovered in plants and some animals is called RNAi.
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RNA interference rebooted - Nature.com

RNA interference rebooted - Nature.com | RNAi | Scoop.it
RNA interference rebooted
Nature.com
After a rocky start, RNA interference (RNAi), a gene-silencing technique that won the 2006 Nobel Prize in Physiology or Medicine, is gaining momentum.
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Deepak Chopra On How To Modify Your Own Genes - Huffington Post

Deepak Chopra On How To Modify Your Own Genes - Huffington Post | RNAi | Scoop.it
Deepak Chopra On How To Modify Your Own Genes
Huffington Post
Though not a typical outcome, there have been reports of such modifications being passed onto subsequent generations, in what's known as transgenerational epigenetic evolution.
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Epigenetics shows differences between Homo sapiens and Neanderthals - Jerusalem Post

Epigenetics shows differences between Homo sapiens and Neanderthals - Jerusalem Post | RNAi | Scoop.it
Epigenetics shows differences between Homo sapiens and Neanderthals
Jerusalem Post
Rather, chemical modifications to the DNA can efficiently turn genes on and off without changing the sequence.
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Expanding the power of RNA interference

Expanding the power of RNA interference | RNAi | Scoop.it
RNA carried by new nanoparticles can silence genes in many organs, could be deployed to treat cancer. (RT @MITEngineering: #MIT researchers achieve most potent RNAi gene silencing to date.
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Silencing HIV: a new approach in viral reservoir stabilization | 100 ...

Silencing HIV: a new approach in viral reservoir stabilization | 100 ... | RNAi | Scoop.it
The discovery of small interfering RNA or silencing RNA (siRNA) is only recent and was first described in plants as a 'post-transcriptional gene silencing'4. siRNA have be proven to play a crucial role in gene expression and ...
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Swiss drug maker Novartis cutting RNA interference research group in Cambridge - Boston Globe

Swiss drug maker Novartis cutting RNA interference research group in Cambridge - Boston Globe | RNAi | Scoop.it
Swiss drug maker Novartis cutting RNA interference research group in Cambridge Boston Globe Swiss drug maker Novartis AG said Monday it is cutting back on a research program in Cambridge trying to develop drugs using a gene-silencing technology...
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Genetic Weapon Against Insects Raises Hope and Fear in Farming

Genetic Weapon Against Insects Raises Hope and Fear in Farming | RNAi | Scoop.it
Scientists, looking for new weapons against insect pests in farming, have developed gene-silencing agents. But skeptics are concerned about potential threats to nontarget insects and even humans.
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Gene silencing instructions acquired through 'molecular memory' tags on chromatin

Gene silencing instructions acquired through 'molecular memory' tags on chromatin | RNAi | Scoop.it
Scientists at Indiana University have unlocked one of the mysteries of modern genetics: how acquired traits can be passed between generations in a process called epigenetic inheritance. The new work finds that cells don't know to silence some genes based on information hardwired into their DNA sequences, ...
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Gene Therapy For Down Syndrome (Video) - Mobile Magazine

Gene Therapy For Down Syndrome (Video) - Mobile Magazine | RNAi | Scoop.it
Mobile Magazine
Gene Therapy For Down Syndrome (Video)
Mobile Magazine
The treatment involves using the XIST gene to turn off the extra chromosome 21 via a technique called “genome editing”.
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How to regrow your head - Nature.com

How to regrow your head - Nature.com | RNAi | Scoop.it
How to regrow your head
Nature.com
All three studies looked at Wnt genes, which code for a series of enzymes that relay information from outside the cell to the nucleus, eventually producing proteins called β-catenins, which regulate gene expression.
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Progressive 35S promoter methylation increases rapidly during ...

Progressive 35S promoter methylation increases rapidly during ... | RNAi | Scoop.it
A transgene can be epigenetically silenced by a process called RNA directed DNA methylation (RdDM), which can be seen as a heritable loss of gene expression. The spontaneous nature of transgene silencing has been ...
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How to build a Neanderthal

How to build a Neanderthal | RNAi | Scoop.it
Epigenetic maps help to explain how archaic humans differed from modern ones despite having very similar DNA sequences.
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RNAi: Another Reason to Cheer for Basic Research - Open Exchange

RNAi: Another Reason to Cheer for Basic Research - Open Exchange | RNAi | Scoop.it
RNAi is a valuable research tool and an important part of drug discovery, an endpoint in the twisty road that is basic research. (Let’s hear it for #basicresearch! #RNAi would be nowhere without it.
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RNAi isn’t ready to be silenced — Vector

RNAi isn’t ready to be silenced — Vector | RNAi | Scoop.it
Boston Children's Hospital's blog about science, research, and clinical innovation in pediatric and adult medicine.
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Fear-Controlling Gene May Be Turned Off; Researchers Discover The Switch - Medical Daily

Fear-Controlling Gene May Be Turned Off; Researchers Discover The Switch - Medical Daily | RNAi | Scoop.it
Medical Daily
Fear-Controlling Gene May Be Turned Off; Researchers Discover The Switch
Medical Daily
Epigenetics is the study of long-term alterations to hereditary genes.
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Novel RNAi Therapy Silences Mutated Huntington's Disease Gene and Reduces Symptoms

Novel RNAi Therapy Silences Mutated Huntington's Disease Gene and Reduces Symptoms | RNAi | Scoop.it
Novel RNAi Therapy Silences Mutated Huntington's Disease Gene and Reduces Symptoms (RT @mattwardfromage: Novel RNAi Therapy Silences Mutated Huntington’s Disease Gene and Reduces Symptoms http://t.co/U9C8TDjR76)...
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On the Trail of Fire Ant Pheromones - Agricultural Research

On the Trail of Fire Ant Pheromones - Agricultural Research | RNAi | Scoop.it
On the Trail of Fire Ant Pheromones Agricultural Research He and Vander Meer also identified the DNA sequence of both the PBAN gene and receptor gene, which allowed them to test the function of PBAN in trail pheromone production using a new...
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Monsanto Moves RNAi-based Pest-resistant Corn into Final Stage of Development | Gene Silencing News | RNAi | GenomeWeb

 
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Next generation of insect-control traits for corn | Corn Rootworm Traits content from Farm Industry News

Next generation of insect-control traits for corn | Corn Rootworm Traits content from Farm Industry News | RNAi | Scoop.it
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Citrus tristeza virus-based RNAi in citrus plants induces gene silencing in Diaphorina citri, a phloem-sap sucking insect vector of citrus greening disease (Huanglongbing)

Citrus tristeza virus-based RNAi in citrus plants induces gene silencing in Diaphorina citri, a phloem-sap sucking insect vector of citrus greening disease (Huanglongbing) | RNAi | Scoop.it
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Scientists Control Genes with Light: New Method for Understanding Function - Science World Report

Scientists Control Genes with Light: New Method for Understanding Function - Science World Report | RNAi | Scoop.it
Scientists Control Genes with Light: New Method for Understanding Function
Science World Report
There are other applications, though, including research into epigenetic modification.
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Gene Silencing Is Golden - Scientist

Scientist
Gene Silencing Is Golden
Scientist
Even though RNAi screening techniques have improved in recent years, with libraries stocked with more RNA probes for each gene that are more effective at knocking down their targets, there are pitfalls.
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