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CALS Research, NCSU's insight:
"Keeping up with current scientific literature is a daunting task," write Matt Shipman, "considering that hundreds to thousands of papers are published each day. Now researchers from NC State University have developed a computer program to help them evaluate and rank scientific articles in their field.
The researchers use a text-mining algorithm to prioritize research papers to read and include in their Comparative Toxicogenomics Database (CTD), a public database which manually curates and codes data from the scientific literature describing how environmental chemicals interact with genes to affect human health.
"Over 33,000 scientific papers have been published on heavy metal toxicity alone, going as far back as 1926,” explains Dr. Allan Peter Davis, a biocuration project manager for CTD at NC State who worked on the project and co-lead author of an article on the work.'“We simply can’t read and code them all. And, with the help of this new algorithm, we don’t have to'.”
CALS biologists Thomas Wiegers, Cynthia Grondin Murphy & Carolyn Mattingly worked with Dr. Davis and colleagues at The Mount Desert Island Biological Laboratory on the NIEHS-funded project.
Dr. Christian Melander's team has enhanced the potency of a naturally-derived compound he and Dr. John Cavanagh discovered, which has bioactivity against methicillin resistant Staphyloccus aureus, known as MRSA. Click the headline to learn more about today 's story.
And read about the earlier work here:
Link to full article (abstract free; full article may require subscription)