Build engaged audiences through publishing by curation.
|Current selected tag: #toxins. Clear.|
Your new post is loading...
CALS Research, NCSU's insight:
"Keeping up with current scientific literature is a daunting task," write Matt Shipman, "considering that hundreds to thousands of papers are published each day. Now researchers from NC State University have developed a computer program to help them evaluate and rank scientific articles in their field.
The researchers use a text-mining algorithm to prioritize research papers to read and include in their Comparative Toxicogenomics Database (CTD), a public database which manually curates and codes data from the scientific literature describing how environmental chemicals interact with genes to affect human health.
"Over 33,000 scientific papers have been published on heavy metal toxicity alone, going as far back as 1926,” explains Dr. Allan Peter Davis, a biocuration project manager for CTD at NC State who worked on the project and co-lead author of an article on the work.'“We simply can’t read and code them all. And, with the help of this new algorithm, we don’t have to'.”
CALS biologists Thomas Wiegers, Cynthia Grondin Murphy & Carolyn Mattingly worked with Dr. Davis and colleagues at The Mount Desert Island Biological Laboratory on the NIEHS-funded project.
"New research led by researchers at North Carolina State University shows that exposure to the chemical bisphenol A (BPA) early in life results in high levels of anxiety by causing significant gene expression changes in a specific region of the brain called the amygdala. The researchers also found that a soy-rich diet can mitigate these effects.
“We knew that BPA could cause anxiety in a variety of species, and wanted to begin to understand why and how that happens,” says Dr. Heather Patisaul, Associate Professor of Biology at NC State and lead author of a paper describing the work. BPA is a chemical used in a wide variety of polycarbonate plastics and epoxy resins, and is used in consumer products such as some food containers."