Research Capacity-Building in Africa
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Australian News - Traditional Indian medicines seized in Australia

Australian News - Traditional Indian medicines seized in Australia | Research Capacity-Building in Africa | Scoop.it
Australian health authorities raided Indian grocery stores in Sydney, seizing traditional medicines they fear may cause lead poisoning.
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Scientists decry ‘the worst case of scientific censorship since the church banned Copernicus’

Scientists decry ‘the worst case of scientific censorship since the church banned Copernicus’ | Research Capacity-Building in Africa | Scoop.it
By Kate Kelland LONDON (Reuters) – The outlawing of drugs such as cannabis, magic mushrooms and other psychoactive substances amounts to scientific censorship and is hampering research into potentially important medicinal uses, leading scientists...

Via Iam Legion
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Outlawing drugs like marijuana censors science, researchers say - Fox News

The Guardian Outlawing drugs like marijuana censors science, researchers say Fox News The outlawing of drugs such as cannabis, magic mushrooms and other psychoactive substances amounts to scientific censorship and is hampering research into...

Via VERONICA LESTER
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With drug-loaded nanogel, Yale researchers attack cancerous tumors

With drug-loaded nanogel, Yale researchers attack cancerous tumors | Research Capacity-Building in Africa | Scoop.it

Yale University scientists have developed a new mechanism for attacking cancerous tumors that intensifies the body’s immune response while simultaneously weakening the tumor’s ability to resist it. Tumors — in this case metastatic melanomas, or spreading skin cancers — are adept at overcoming their host’s natural defenses, in part by emitting agents that disrupt production and operation of the immune system.

 

The Yale team developed a new biodegradable nanoparticle that delivers a combination of two very different therapeutic agents to tumor sites, gradually releasing the agents into the tumor vasculature. One agent, a large soluble protein called a cytokine, stimulates the body’s innate immune response. The other, a small-molecule inhibitor, interferes with the tumor’s ability to suppress the immune response. Other drug combinations are possible.

 

In tests on live mice, the double-loaded particle, called a nanogel, significantly delayed tumor growth and increased survival, the researchers report. They administered the nanogels intravenously and, in separate experiments, directly into the tumors. Further animal tests are planned.


Via Dr. Stefan Gruenwald
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21st Century natural product research and drug development and traditional medicines

21st Century natural product research and drug development and traditional medicines | Research Capacity-Building in Africa | Scoop.it

Natural products and related structures are essential sources of new pharmaceuticals, because of the immense variety of functionally relevant secondary metabolites of microbial and plant species. Furthermore, the development of powerful analytical tools based upon genomics, proteomics, metabolomics, bioinformatics and other 21st century technologies are greatly expediting identification and characterization of these natural products. Here we discuss the synergistic and reciprocal benefits of linking these 'omics technologies with robust ethnobotanical and ethnomedical studies of traditional medicines, to provide critically needed improved medicines and treatments that are inexpensive, accessible, safe and reliable. However, careless application of modern technologies can challenge traditional knowledge and biodiversity that are the foundation of traditional medicines. To address such challenges while fulfilling the need for improved (and new) medicines, we encourage the development of Regional Centres of 'omics Technologies functionally linked with Regional Centres of Genetic Resources, especially in regions of the world where use of traditional medicines is prevalent and essential for health.

 

Linh T. Ngo ,  Joseph I. Okogun and William R. Folk

Nat. Prod. Rep., 2013, Advance Article

DOI: 10.1039/C3NP20120A

 

 


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Poland Biological and Biosimilars Drug Market 2013 Analysis & 2015 Forecasts in New Research Report at RnRMarketResearch.com

Poland Biological and Biosimilars Drug Market 2013 Analysis & 2015 Forecasts in New Research Report at RnRMarketResearch.com | Research Capacity-Building in Africa | Scoop.it
RnRMarketResearch.com adds Latest Report on “Biological and Biosimilars Drug Market in Poland 2013” to its store.

Via Thomas Faltin
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LSUHSC research discovers new drug target for metastatic breast cancer

LSUHSC research discovers new drug target for metastatic breast cancer | Research Capacity-Building in Africa | Scoop.it

"Research led by Dr. Suresh Alahari, Professor of Biochemistry and Molecular Biology at LSU Health Sciences Center New Orleans, is the first to report that two specific tumor suppressor genes work in concert to inhibit the growth and spread of breast tumor cells to the lungs. The research is published this week online in the Journal of Biological Chemistry.



Via Susan Zager
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Susan Zager's curator insight, April 16, 2013 10:33 AM

"Working in a mouse model, the LSUHSC research team studied LKB1, an enzyme that functions as a tumor suppressor in the small intestine, and Nischarin, a novel protein that regulates breast cancer cell migration and movement discovered by Dr. Alahari in 2000. Thirty percent of lung adenocarcinomas have an LKB1 gene mutation, and high levels of the LKB1 protein in breast cancer cells have been shown to significantly inhibit tumor growth. The LKB1-interacting protein is also structurally similar to Nischarin. The researchers suspected that the two suppressors might relate to each other, and they did in fact discover a functional and biochemical link between them.""

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Seralini Study on GMOs Republished After Unprecedented Scientific Censorship - Daily Health Post

Seralini Study on GMOs Republished After Unprecedented Scientific Censorship - Daily Health Post | Research Capacity-Building in Africa | Scoop.it
Read all about it here. (Seralini Study on GMOs Republished After Unprecedented Scientific Censorship:

http://t.co/eG51drGtNe)
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Two new mysterious giant holes found in Siberia, scientists puzzled | Gizmodo.com

Two new mysterious giant holes found in Siberia, scientists puzzled | Gizmodo.com | Research Capacity-Building in Africa | Scoop.it

Scientists have found two new mysterious giant holes in Siberia, like the one that appeared in Siberia two weeks ago.


The new craters are smaller than the first but they share a similar structure.


Scientists are still puzzled by the origin of these formations.


Here are all the details:


Click headline to read more and view pix--


Via Chuck Sherwood, Senior Associate, TeleDimensions, Inc
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