Journal of Cardiovascular Magnetic Resonance is the official publication of the Society for Cardiovascular Magnetic Resonance. As the only journal devoted exclusively to cardiovascular magnetic resonance, JCMR provides an international forum for communicating the latest findings and state-of-the-art reviews on the burgeoning field of cardiovascular magnetic resonance imaging and spectroscopy, filling a critical gap in the science and practice of cardiology and related disciplines. The journal's open access format facilitates wide distribution of published articles ensuring authors work is highly visible.
(Phys.org)—Similar to the way that a conventional magnetic resonance imaging (MRI) machine uses large magnets to generate 3D images, physicists have developed a proposal for a quantum nano-MRI machine that would use th
Idiopathic scoliosis (IS), the most common spinal deformity, affects otherwise healthy children and adolescents during growth. The aetiology is still unknown, although genetic factors are believed to be important. The present review corroborates the understanding of IS as a complex disease with a polygenic background. Presumably IS can be due to a spectrum of genetic risk variants, ranging from very rare or even private to very common. The most promising candidate genes are highlighted.
When Children’s Hospital Los Angeles cardiologists found evidence that a portion of Nate Yamane’s pulmonary artery they had repaired once before was again narrowing, pediatric interventional cardiologist Frank Ing, M.D., decided they needed to insert a stent to keep the right artery open.
With new findings about MRI's ability to improve early diagnosis of breast cancer in all women – not only those at high risk – researchers in Germany say MRI can serve as a useful supplemental screening tool for women at average risk, especially those wit
Depending on your location and how high you are above the ground, flying can expose you to some pretty intense cosmic radiation, according to NASA. Here's an animated graphic showing the levels for November 14, 2012.
Ligamentum flavum (LF) hypertrophy is a common cause of lumbar spinal stenosis and is thought to be degeneration-driven. Developmental spinal stenosis (DSS) is characterized by pre-existing narrowed spinal canals and is likely a developmental problem that occurs in childhood. In these cases, the LF may demonstrate different characteristics as compared to degeneration-driven stenosis. Thus, this study aimed to investigate the relationship between histological changes of LF and canal size. Patients who had surgical decompression for lumbar spinal stenosis were prospectively recruited and divided into three groups (critical DSS, relative DSS and non-DSS) based on previously defined anteroposterior bony spinal canal diameter measurements on MRI. The degree of disc degeneration and LF thickness were also measured from L1 to S1. Surgical LF specimens were retrieved for histological assessment of fibrotic grade and area of fibrosis. A total of 19 females and 15 males (110 LF specimens) with an overall mean age of 65.9 years (SD ± 9.8 years) were recruited. DSS was found to have a significant negative correlation (p < 0.001) with LF thickness, its fibrotic grade and area of fibrosis (%). Non-DSS exhibited a significant positive relationship with the degree of LF fibrosis. Disc degeneration and LF thickness had no correlation with LF histology. Our study is the first to definitively note that degeneration is the cause of LF fibrosis in non-DSS patients; however, in contrast, an inverse relationship exists between canal size and LF fibrosis in DSS patients, suggesting a different pathomechanism. Hence, despite a similar degree of LF thickness, DSS patients have LF with less fibrosis compared with non-DSS patients. Further investigation of the cause of LF changes in DSS is necessary to understand this relationship.
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