Medicine and Psychiatry
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Changing brains: why neuroscience is ending the Prozac era

Changing brains: why neuroscience is ending the Prozac era | Medicine and Psychiatry | Scoop.it
The big money has moved from developing psychiatric drugs to manipulating our brain networks, writes Vaughan Bell

Via Sandeep Gautam
Ziggi Ivan Santini's insight:

This is either exceedingly good news or extremely dangerous...

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Joe Stafura's curator insight, September 23, 2013 10:30 AM

The pharma business is just one of the many areas where the new understanding of the brain changes the options; education, economics and policy development and business management are all areas that will be disrupted over the next decade. The greatest inertia to overcome is the desire of many to cling to superstitious or profitable scams that are attractive but ineffective except in the creation of profits.

Venitta Lateer's comment, September 25, 2013 8:09 PM
You need to look into what is called Non-Leathal, it is used by the Police & Military it cab do all that and much more, I can not look into it, myself, as i am under a investigation, and they make sure that I can not get a hold of dam near anything i need, that is unless it has the ability to make me look crazy or paranoid, thus your post, lol. But if you really want to do that kind of thing, and work, you really should look into Non-Leathal

Your article was AWESOME !!! Posted it on Facebook :)
P.S. NO I do not think that you are in on ANYTHING with the FBI over my case, they just make sure that I find things like this, lol, Sigh :(
William baldwin's curator insight, January 4, 2015 11:31 PM

Change the way we lead people through Brain Science

Medicine and Psychiatry
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Here’s how to address the opioid epidemic

Here’s how to address the opioid epidemic | Medicine and Psychiatry | Scoop.it

Most expert recommendations focus on seven key areas: increase prevention; increase insurance coverage; improve the availability of treatment including medications like buprenorphine (an anti-craving drug); reasonably restrict prescribing; decriminalize addiction to allow people to safely receive care; address the social determinants of health such as unemployment, abuse and poverty; and create public awareness to reduce stigma. These are all sensible recommendations we need to implement immediately; they are rooted in solid public health evidence. But they won’t turn the tide. That’s because they leave several important barriers unsolved. Here is what else is needed and why.

Ziggi Ivan Santini's insight:

Addiction is a chronic disease requiring long-term, data-driven support – identification, evidence-based treatment, and coaching. We wouldn’t discharge someone with heart failure after 28 days and wish them good luck. We need to stick with these folks through thick and thin, just as we do for every other illness. Some very valuable points offered here.

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Brain training shows promise for patients with bipolar disorder

Brain training shows promise for patients with bipolar disorder | Medicine and Psychiatry | Scoop.it
Researchers at McLean Hospital, an affiliate of Harvard Medical School, have discovered for the first time that computerized brain training can result in improved cognitive skills in individuals with bipolar disorder.
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Computerized brain training can result in improved cognitive skills in individuals with bipolar disorder, researchers have discovered for the first time.

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Magic Mushrooms Found to Be "Resetting" Brain Circuits in Depressed People

Magic Mushrooms Found to Be "Resetting" Brain Circuits in Depressed People | Medicine and Psychiatry | Scoop.it

Psychedelics like lysergic acid diethylamide (LSD) and psilocybin are popular for their use as party drugs, but less so for what researchers claim to be their therapeutic effects - which has been a major focus for a number of clinical trials in the last decade. Magic mushrooms, for example, have been the focus of some recent work that saw how it could help with treating some of the symptoms of clinical depression.

Ziggi Ivan Santini's insight:

Study highlights how psilocybin give patients a "kick start" in fighting clinical depression.

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Premature Birth Linked to Older 'Brain Age' in Adulthood

Premature Birth Linked to Older 'Brain Age' in Adulthood | Medicine and Psychiatry | Scoop.it
A Neuroimaging study, conducted by King’s College London researchers, reveals accelerated brain aging during adulthood for those born very prematurely. Researchers noted those born preterm tended to have smaller global gray matter volume and some brain structure changes in areas associate with spatial abilities and behavior control in adulthood.
Ziggi Ivan Santini's insight:

Babies born very prematurely show accelerated brain development in adult life, as their brains look ‘older’ compared to non-premature babies.

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The FDA Has Labeled Ecstasy A "Breakthrough Therapy" for PTSD

The FDA Has Labeled Ecstasy A "Breakthrough Therapy" for PTSD | Medicine and Psychiatry | Scoop.it
The U.S. Food and Drug Administration (FDA) has determined that 3,4-methylenedioxymethamphetamine (MDMA), also known as ecstasy, is a “breakthrough therapy” in the treatment of post-traumatic stress disorder (PTSD). Thanks to this designation, the drug could have a faster path to pharmaceutical approval.
Ziggi Ivan Santini's insight:

The FDA has designated 3,4-methylenedioxymethamphetamine (better known as ecstasy) a "breakthrough therapy" for the treatment of PTSD. If approved for medicinal use, the drug could help the nearly 8 million people who suffer form PTSD yearly.

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First human embryo editing experiment in U.S. ‘corrects’ gene for heart condition

First human embryo editing experiment in U.S. ‘corrects’ gene for heart condition | Medicine and Psychiatry | Scoop.it
This is the first time gene editing on human embryos has been conducted in the United States. Researchers said in interviews this week that they consider their work very basic. The embryos were allowed to grow for only a few days, and there was never any intention to implant them to create a pregnancy. But they also acknowledged that they will continue to move forward with the science, with the ultimate goal of being able to “correct” disease-causing genes in embryos that will develop into babies.
Ziggi Ivan Santini's insight:

Scientists have successfully edited the DNA of human embryos to erase a heritable heart condition, cracking open the doors to a controversial new era in medicine.

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Drug costs vary by more than 600% in study of 10 high-income countries

Drug costs vary by more than 600% in study of 10 high-income countries | Medicine and Psychiatry | Scoop.it
The study looked at data on the volume and daily cost of primary care prescriptions in 10 high-income countries with universal health care: Australia, Canada, France, Germany, the Netherlands, New Zealand, Norway, Sweden, Switzerland and the United Kingdom. Because of the high cost of pharmaceutical drugs and the lack of universal health care, the United States was not included.
Ziggi Ivan Santini's insight:

In a study of 10 high-income countries with universal health care, costs for prescription drugs in 6 of the largest categories of primary care medicines varied by more than 600%.

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Pig brain cells implanted into brains of people with Parkinson’s

Pig brain cells implanted into brains of people with Parkinson’s | Medicine and Psychiatry | Scoop.it
Living Cell Technologies, based in Auckland, New Zealand, has been developing a treatment that uses cells from the choroid plexus in pigs. This brain structure makes a cocktail of growth factors and signalling molecules known to help keep nerve cells healthy.
Ziggi Ivan Santini's insight:

Would you have pig cells implanted in your brain? Some people with Parkinson’s disease have, in the hope it will stop their disease progressing. The approach is still in the early stages of testing, but initial results from four people look promising, with all showing some improvement 18 months after surgery.

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Common painkillers linked to increased risk of heart attack

Common painkillers linked to increased risk of heart attack | Medicine and Psychiatry | Scoop.it
This group of drugs includes ibuprofen, diclofenac, celecoxib and naproxen, which are available over the counter or by prescription for higher doses, to relieve pain or fever resulting from a range of causes, including flu, headaches, back pain and menstrual cramps. Their range of uses also means they are often taken as needed, for short periods of time.
Ziggi Ivan Santini's insight:

Taking even over-the-counter doses of common painkillers known as NSAIDs -- nonsteroidal anti-inflammatory drugs -- has been linked to an increased risk of heart attack in a new study.

The likelihood of experiencing a heart attack was calculated to increase by an average of 20% to 50%, compared with someone not taking the drugs, regardless of the dosage and amount of time the medications are taken.
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The Lazarus phenomenon: When the 'dead' come back to life

The Lazarus phenomenon: When the 'dead' come back to life | Medicine and Psychiatry | Scoop.it
Her heart had stopped beating and she was no longer breathing. Janina Kolkiewicz was declared dead. At 91 years old, she had lived a long life. But she was not about to stop living it. Eleven hours later, she awoke in the hospital mortuary with a craving for tea and pancakes. As inconceivable as it sounds, Kolkiewicz is just one of many people said to have "risen from the dead."
Ziggi Ivan Santini's insight:

In 2014, a 78-year-old man from Mississippi was declared dead after a hospice nurse found him with no pulse. The next day, he woke up in a body bag at the morgue.

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Vicente Franco's comment, May 28, 12:31 PM
In Newborns have also been described
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Brain stent to let five paralysed people control exoskeleton

Brain stent to let five paralysed people control exoskeleton | Medicine and Psychiatry | Scoop.it
Several groups are developing brain-machine interfaces that allow people who are paralysed to operate a bionic exoskeleton just by thinking about it. These devices decode electrical brain signals and translate them into movement of robotic limbs.
Ziggi Ivan Santini's insight:

MIND CONTROL without the side effects. That’s the aim of a device that could help people control robotic limbs using thought alone – without the need for brain surgery.

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London University finds link between mental illness and heart disease

London University finds link between mental illness and heart disease | Medicine and Psychiatry | Scoop.it
Researchers who analysed data on more than three-million patients found significant links between cardiovascular disease and conditions such as schizophrenia, bipolar disorder and major depression.
Ziggi Ivan Santini's insight:

A large study conducted at King's College London has found that having a serious mental illness (SMI) significantly increases the risk of premature death from heart disease.

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Mª del Mar Miralles Pascual's curator insight, May 15, 5:16 PM
A large study conducted at King's College London has found that having a serious mental illness (SMI) significantly increases the risk of premature death from heart disease.
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After suicide attempt, a phone call could save a life

After suicide attempt, a phone call could save a life | Medicine and Psychiatry | Scoop.it
A simple phone call can make a big difference to someone who's attempted suicide and may be contemplating another try.
Ziggi Ivan Santini's insight:

New study finds that follow-up phone calls after a suicidal patient is discharged from a hospital emergency department reduces future suicide attempts by 30 percent.

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Machine learning identifies breast lesions likely to become cancer

Machine learning identifies breast lesions likely to become cancer | Medicine and Psychiatry | Scoop.it
A machine learning tool can help identify which high-risk breast lesions are likely to become cancerous, according to a new study appearing online in the journal Radiology. Researchers said the technology has the potential to reduce unnecessary surgeries.
Ziggi Ivan Santini's insight:

When there's this much uncertainty in data, machine learning is exactly the tool that we need to improve detection and prevent overtreatment.

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Study Finds A Substantial “Very Strong” Link Between GMOs & Multiple Diseases

Study Finds A Substantial “Very Strong” Link Between GMOs & Multiple Diseases | Medicine and Psychiatry | Scoop.it
It’s no secret that we are living in a time where chronic disease continues to rise at an exponential rate, especially within the past couple of decades. New evidence continues to mount suggesting that Genetically Modified Organisms (more specifically GM food) might have played, and do play a key role in those statistics.
Ziggi Ivan Santini's insight:

Data continue to show strong correlations between the increasing use of GMO and a multitude of diseases.

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After 15 Years in a Vegetative State, Nerve Stimulation Restores Consciousness

After 15 Years in a Vegetative State, Nerve Stimulation Restores Consciousness | Medicine and Psychiatry | Scoop.it
A 35-year-old man who had been in a vegetative state for 15 years after a car accident has shown signs of consciousness after neurosurgeons implanted a vagus nerve stimulator into his chest. The findings reported in Current Biology on September 25 show that vagus nerve stimulation (VNS)–a treatment already in use for epilepsy and depression–can help to restore consciousness even after many years in a vegetative state.
Ziggi Ivan Santini's insight:

Researchers have been able to restore consciousness to a patient who has been in a vegetative state for 15 years.

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People with schizophrenia have threefold risk of dying

People with schizophrenia have threefold risk of dying | Medicine and Psychiatry | Scoop.it
This large study looked at all deaths in Ontario over a 20-year period (1993-2012)—more than 1.6 million deaths—to understand trends in schizophrenia. Of these, 31 349 were deaths of people with schizophrenia and more were female, younger and living in lower-income neighbourhoods compared with the general population. Despite increases in life expectancy, people with schizophrenia died 8 years younger than the general population (age at death increased from an average of 64.7 to 67.4 years of age from 1993 to 2012 among people with schizophrenia compared with 73.3 to 76.7 years in general population). Death from all causes decreased 35% in parallel in both groups.
Ziggi Ivan Santini's insight:

People with schizophrenia are three times more likely to die, and die younger, than the general population.

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Scientists use gene editing to eliminate viruses in live pigs

Scientists use gene editing to eliminate viruses in live pigs | Medicine and Psychiatry | Scoop.it
Scientists have edited the pig genome to deactivate a family of retroviruses. The results hold important implications for transplant medicine in humans.
Ziggi Ivan Santini's insight:

Organ transplants from pigs are a step closer, after the birth of piglets that have had harmful viruses in their DNA inactivated using CRISPR gene editing.

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Researchers are turning sperm into cancer-fighting 'robots'

Researchers are turning sperm into cancer-fighting 'robots' | Medicine and Psychiatry | Scoop.it
A team of researchers from the Institute for Integrative Nanosciences in Germany has created a unique drug delivery system designed specifically for diseases of the female reproductive tract such as gynaecological cancer, endometriosis, and pelvic inflammatory diseases.
Ziggi Ivan Santini's insight:

Sperm are evolutionarily programmed to travel through the reproductive system and now scientists are using this to their advantage. They’re testing bionic bovine sperm to deliver cancer-treating drugs directly to tumors.

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Burden of physical health conditions linked to increased risk of suicide

Burden of physical health conditions linked to increased risk of suicide | Medicine and Psychiatry | Scoop.it
Suicide continues to be a major driver of mortality in the United States. Each year, more than 45,000 people die by suicide and in the past 15 years, the suicide mortality rate has risen by an alarming 24%. A new study in the American Journal of Preventive Medicine examines how illness plays a role in suicide risk. Researchers found that 17 physical health conditions, ailments such as back pain, diabetes, and heart disease, were associated with an increased risk of suicide. Two of the conditions — sleep disorders and HIV/AIDS — represented a greater than twofold increase, while traumatic brain injury made individuals nine times more likely to die by suicide.
Ziggi Ivan Santini's insight:

Many people who die by suicide do not have a prior mental health diagnosis, which means that patients at an increased risk for self-harm are somehow being missed by the mainstream healthcare system. In an attempt to gain some insight into the disturbing rise in suicide rates and possible novel interventions, researchers examined whether there is a link between physical illness and suicide risk.

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Scientists identify 100 memory genes, open new avenues of brain study

Scientists identify 100 memory genes, open new avenues of brain study | Medicine and Psychiatry | Scoop.it
A study at the Peter O'Donnell Jr. Brain Institute includes the results of a new strategy to identify genes that underlie specific brain processes. This strategy may eventually help scientists develop treatments for patients with memory impairments.
Ziggi Ivan Santini's insight:

Scientists have identified more than 100 genes linked to memory, opening new avenues of research to better understand memory processing in the human brain.

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How the HPV vaccine works

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This video explains how the HPV vaccine works, possible benefits and risks for adverse effects.

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Mind-controlled device helps stroke patients retrain brains to move paralyzed hands

Mind-controlled device helps stroke patients retrain brains to move paralyzed hands | Medicine and Psychiatry | Scoop.it

Medical resident Jarod Roland, MD, tries out a device that detects electrical activity in his brain and causes his hand to open and close in response to brain signals. A new study shows that this device can help chronic stroke patients recover some control over their paralyzed limbs. Stroke patients who learned to use their minds to open and close a device fitted over their paralyzed hands gained some control over their hands, according to a new study from Washington University School of Medicine in St. Louis.

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By mentally controlling a device with the help of a brain-computer interface, participants trained uninjured parts of their brains to take over functions previously performed by injured areas of the brain.

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‘I knew they were sugar pills but I felt fantastic’ – the rise of open-label placebos

‘I knew they were sugar pills but I felt fantastic’ – the rise of open-label placebos | Medicine and Psychiatry | Scoop.it
IBS patient Linda Buonanno knew the pills she was given contained no active drugs, yet they had an immediate effect on her condition. So can placebos play a useful medical role?
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Open-label placebos – those the patient knows they are taking – can improve symptoms in a range of conditions.

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Can Psychedelic Drugs Treat Mental Illness? Scientists Need Your Help To Find Out

Can Psychedelic Drugs Treat Mental Illness? Scientists Need Your Help To Find Out | Medicine and Psychiatry | Scoop.it
A new crowdfunding campaign seeks to raise $2 million to advance promising research that the government has largely neglected.
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Help support the future of psychedelic research. Donate via link here.

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