Preventive Medicine
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Painkillers linked to high blood pressure | ISRAEL21c

Painkillers linked to high blood pressure | ISRAEL21c | Preventive Medicine | Scoop.it
Pain relievers may be causing a rise in blood pressure, cautions a Tel Aviv University researcher.
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Preventive Medicine
Migrating Healthcare From Reactive To Predictive And Beyond
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The science behind food cravings

The science behind food cravings | Preventive Medicine | Scoop.it
Exhibition examines the science behind food cravings
ClickTell Consulting's insight:

Notice the term “anti-trigger” used in the video (at 1:22). This is a way of avoiding a usually advertising/neuromarketing driven urge for a person to make an impulse purchase - such as suddenly stopping in a high street to buy certain food once that person has been exposed to a certain smell.

 

In our last year’s  blog post reply on the Centre For Connected Health we introduced a similar term referred to as “Counterising”, for counteracting advertising. You can read more from here:

 

http://chealthblog.connectedhealth.org/2014/02/03/making-health-addictive-employ-subliminal-messaging/#comment-4764

 

For your convenience the blog post reply in question is also reproduced below:

 

February 28, 2014 12:46 pm

Jo,

A great post. Blended delicately, neuroscience, marketing and advertising can produce the sweetest pill that preventive care of today could wish for.

 

A while back at my company we coined the term “Counterising”, for counteracting advertising. This came about as a result of trying to formulate an effective evidence-based model to encourage a healthy lifestyle in the field of chronic disorders.

 

Needless to say implemented properly insight of this nature offers a tremendously healthy ROI. Why else would companies such Coca-Cola & McDonalds spend as much money as they do in successfully trying to encourage us to buy into their message and product?

 

Sepe Sehati,
ClickTell Consulting

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Could artificial sweeteners be bad for your brain? - Harvard Health Blog

Could artificial sweeteners be bad for your brain? - Harvard Health Blog | Preventive Medicine | Scoop.it
A recent study suggests that artificially sweetened beverages may increase the risk for stroke or dementia, but couldn't establish a clear cause and effect.
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Research shows aspirin could repair tooth decay

Research shows aspirin could repair tooth decay | Preventive Medicine | Scoop.it
Researchers at Queen's University Belfast have discovered that aspirin could reverse the effects of tooth decay resulting in a reduction in the need for fillings. Currently about 7 million fillings are provided by the NH
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'Don't finish the course of antibiotics' - experts turn medical advice on its head

'Don't finish the course of antibiotics' - experts turn medical advice on its head | Preventive Medicine | Scoop.it
Doctors must stop telling patients to finish an entire course of antibiotics because it is driving antimicrobial resistance, a group of eminent specialists has warned.
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Cancer-death button gets jammed by gut bacterium

Cancer-death button gets jammed by gut bacterium | Preventive Medicine | Scoop.it
Researchers at Michigan Medicine and in China showed that a type of bacterium is associated with the recurrence of colorectal cancer and poor outcomes. They found that Fusobacterium nucleatum in the gut can stop chemotherap
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Knee arthroscopy versus conservative management in patients with degenerative knee disease: a systematic review

Objective To determine the effects and complications of arthroscopic surgery compared with conservative management strategies in patients with degenerative knee disease.

Design Systematic review.

Main outcome measures Pain, function, adverse events.

Data sources MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials (CENTRAL), Google Scholar and Open Grey up to August 2016.

Eligibility criteria For effects, randomised clinical trials (RCTs) comparing arthroscopic surgery with a conservative management strategy (including sham surgery) in patients with degenerative knee disease. For complications, RCTs and observational studies.

Review methods Two reviewers independently extracted data and assessed risk of bias for patient-important outcomes. A parallel guideline committee ( BMJ Rapid Recommendations) provided input on the design and interpretation of the systematic review, including selection of patient-important outcomes. We used the GRADE approach to rate the certainty (quality) of the evidence.

Results We included 13 RCTs and 12 observational studies. With respect to pain, the review identified high-certainty evidence that knee arthroscopy results in a very small reduction in pain up to 3 months (mean difference =5.4 on a 100-point scale, 95% CI 2.0 to 8.8) and very small or no pain reduction up to 2 years (mean difference =3.1, 95% CI −0.2 to 6.4) when compared with conservative management. With respect to function, the review identified moderate-certainty evidence that knee arthroscopy results in a very small improvement in the short term (mean difference =4.9 on a 100-point scale, 95% CI 1.5 to 8.4) and very small or no improved function up to 2 years (mean difference =3.2, 95% CI −0.5 to 6.8). Alternative presentations of magnitude of effect, and associated sensitivity analyses, were consistent with the findings of the primary analysis. Low-quality evidence suggested a very low probability of serious complications after knee arthroscopy.

Conclusions Over the long term, patients who undergo knee arthroscopy versus those who receive conservative management strategies do not have important benefits in pain or function.

Trial registration number PROSPERO CRD42016046242.
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Risk of death among users of Proton Pump Inhibitors: a longitudinal observational cohort study of United States veterans

Objective Proton pump inhibitors (PPIs) are widely used, and their use is associated with increased risk of adverse events. However, whether PPI use is associated with excess risk of death is unknown. We aimed to examine the association between PPI use and risk of all-cause mortality.

Design Longitudinal observational cohort study.

Setting US Department of Veterans Affairs.

Participants Primary cohort of new users of PPI or histamine H2 receptor antagonists (H2 blockers) (n=349 312); additional cohorts included PPI versus no PPI (n=3 288 092) and PPI versus no PPI and no H2 blockers (n=2 887 030).

Main outcome measures Risk of death.

Results Over a median follow-up of 5.71 years (IQR 5.11–6.37), PPI use was associated with increased risk of death compared with H2 blockers use (HR 1.25, CI 1.23 to 1.28). Risk of death associated with PPI use was higher in analyses adjusted for high-dimensional propensity score (HR 1.16, CI 1.13 to 1.18), in two-stage residual inclusion estimation (HR 1.21, CI 1.16 to 1.26) and in 1:1 time-dependent propensity score-matched cohort (HR 1.34, CI 1.29 to 1.39). The risk of death was increased when considering PPI use versus no PPI (HR 1.15, CI 1.14 to 1.15), and PPI use versus no PPI and no H2 blockers (HR 1.23, CI 1.22 to 1.24). Risk of death associated with PPI use was increased among participants without gastrointestinal conditions: PPI versus H2 blockers (HR 1.24, CI 1.21 to 1.27), PPI use versus no PPI (HR 1.19, CI 1.18 to 1.20) and PPI use versus no PPI and no H2 blockers (HR 1.22, CI 1.21 to 1.23). Among new PPI users, there was a graded association between the duration of exposure and the risk of death.

Conclusions The results suggest excess risk of death among PPI users; risk is also increased among those without gastrointestinal conditions and with prolonged duration of use. Limiting PPI use and duration to instances where it is medically indicated may be warranted.
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New study links antibiotic resistance to common household disinfectant triclosan

New study links antibiotic resistance to common household disinfectant triclosan | Preventive Medicine | Scoop.it
Scientists from the University of Birmingham and Norwich Research Park have discovered a link between a major mechanism of antibiotic resistance and resistance to the disinfectant triclosan which is commonly found in domesti
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Response of Local Nitric Oxide Release to Manual Acupuncture and Electrical Heat in Humans: Effects of Reinforcement Methods

Response of Local Nitric Oxide Release to Manual Acupuncture and Electrical Heat in Humans: Effects of Reinforcement Methods | Preventive Medicine | Scoop.it
Evidence-Based Complementary and Alternative Medicine (eCAM) is an international peer-reviewed, Open Access journal that seeks to understand the sources and to encourage rigorous research in this new, yet ancient world of complementary and alternative medicine.
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Why does acupuncture work? Study finds it elevates nitric oxide, leading to pain reduction

Why does acupuncture work? Study finds it elevates nitric oxide, leading to pain reduction | Preventive Medicine | Scoop.it
The use of acupuncture to treat pain dates back to the earliest recorded history in China. Despite centuries of acupuncture, it's still not clear why this method of applying and stimulating tiny needles at certain point
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Study of US seniors strengthens link between air pollution and premature death

Study of US seniors strengthens link between air pollution and premature death | Preventive Medicine | Scoop.it
A new study of 60 million Americans—about 97% of people age 65 and older in the United States—shows that long-term exposure to airborne fine particulate matter (PM2.5) and ozone increases the risk of premature death
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Common water treatments could damage DNA

Common water treatments could damage DNA | Preventive Medicine | Scoop.it
Scientists are warning that a water treatment widely used in developing countries could be damaging the DNA of those drinking it.
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Extra-virgin olive oil preserves memory and protects brain against Alzheimer's: study

Extra-virgin olive oil preserves memory and protects brain against Alzheimer's: study | Preventive Medicine | Scoop.it
The Mediterranean diet, rich in plant-based foods, is associated with a variety of health benefits, including a lower incidence of dementia. Now, researchers at the Lewis Katz School of Medicine at Temple University (LKSOM
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Yoga could complement traditional treatment for depression - Harvard Health Blog

Yoga could complement traditional treatment for depression - Harvard Health Blog | Preventive Medicine | Scoop.it
Research suggests that yoga along with traditional treatment can help depression. More study is needed to evaluate the benefits of specific forms of yoga.
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Gut microbes may influence multiple sclerosis progression

Gut microbes may influence multiple sclerosis progression | Preventive Medicine | Scoop.it
Researchers at UC San Francisco have identified specific gut microbes associated with multiple sclerosis (MS) in human patients, showing that these microbes take part in regulating immune responses in mouse models of th
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Eat fat, live longer? Mouse study shows a high fat diet increases longevity, strength

Eat fat, live longer? Mouse study shows a high fat diet increases longevity, strength | Preventive Medicine | Scoop.it
As more people live into their 80s and 90s, researchers have delved into the issues of health and quality of life during aging. A recent mouse study at the UC Davis School of Veterinary Medicine sheds light on those question
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Richard Haddad Zen Pharma's curator insight, September 11, 7:31 AM

Un médecin américain a écrit dernièrement  un livre "EAT FAT..."   .Oui on sait maintenant que le rejet des matières grasses par les scientifiques américains " au alentours de 1980 avec l’étude de Framingam" n’était qu'un prétexte pour ventre leurs médicaments anti cholestérol et de se débarrasser du même coup des surplus en blé. En fait c'est le blé qui est dangereux  et les huiles avec leur oméga 3 qui est bénéfique  

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Questions over advice to finish courses of antibiotics - Health News - NHS Choices

"Should you finish a course of antibiotics?" asks BBC Online. The question is prompted by a new review suggesting concerns around antibiotic treatment are driven by fears of under-treatment, when we should instead be concerned abou
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Antibiotic use linked to increased risk of precancerous colon polyps - Harvard Health

Antibiotic use linked to increased risk of precancerous colon polyps - Harvard Health | Preventive Medicine | Scoop.it
Data from the Nurses’ Health Study suggests that extended use of antibiotics earlier in life may increase the risk of precancerous adenomatous polyps…
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Coffee, including caffeinated and decaffeinated coffee, and the risk of hepatocellular carcinoma: a systematic review and dose–response meta-analysis

Objectives To examine the association between coffee, including caffeinated and decaffeinated coffee, with hepatocellular carcinoma (HCC) and assess the influence of HCC aetiology and pre-existing liver disease.

Design We performed a systematic review and meta-analysis. We calculated relative risks (RRs) of HCC according to caffeinated and decaffeinated coffee consumption using a random-effects dose–response meta-analysis. We tested for modification of the effect estimate by HCC aetiology and pre-existing liver disease. We judged the quality of evidence using the Grading of Recommendations Assessment, Development and Evaluation (GRADE) criteria.

Results We found 18 cohorts, involving 2 272 642 participants and 2905 cases, and 8 case–control studies, involving 1825 cases and 4652 controls. An extra two cups per day of coffee was associated with a 35% reduction in the risk of HCC (RR 0.65, 95% CI 0.59 to 0.72). The inverse association was weaker for cohorts (RR 0.71, 95% CI 0.65 to 0.77), which were generally of higher quality than case–control studies (RR 0.53, 95% CI 0.41 to 0.69). There was evidence that the association was not significantly altered by stage of liver disease or the presence/absence of high alcohol consumption, high body mass index, type 2 diabetes mellitus, smoking, or hepatitis B and C viruses. An extra two cups of caffeinated and decaffeinated coffee (2 and 3 cohort studies, respectively) were associated with reductions of 27% (RR 0.73, 95% CI 0.63 to 0.85) and 14% (RR 0.86, 95% CI 0.74 to 1.00) in the risk of HCC. However, due to a lack of randomised controlled trials, potential publication bias and there being no accepted definition of coffee, the quality of evidence under the GRADE criteria was ‘very low’.

Conclusions Increased consumption of caffeinated coffee and, to a lesser extent, decaffeinated coffee are associated with reduced risk of HCC, including in pre-existing liver disease. These findings are important given the increasing incidence of HCC globally and its poor prognosis.
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Popular heartburn drugs linked to higher death risk

Popular heartburn drugs linked to higher death risk | Preventive Medicine | Scoop.it
Popular heartburn drugs called proton pump inhibitors (PPIs) have been linked to a variety of health problems, including serious kidney damage, bone fractures and dementia. Now, a new study from Washington University Schoo
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Why does acupuncture work? Study finds it elevates nitric oxide, leading to pain reduction

Why does acupuncture work? Study finds it elevates nitric oxide, leading to pain reduction | Preventive Medicine | Scoop.it
The use of acupuncture to treat pain dates back to the earliest recorded history in China. Despite centuries of acupuncture, it's still not clear why this method of applying and stimulating tiny needles at certain point
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Research suggests association between gut bacteria and emotion

Research suggests association between gut bacteria and emotion | Preventive Medicine | Scoop.it
Researchers have identified gut microbiota that interact with brain regions associated with mood and behavior. This may be the first time that behavioral and neurobiological differences associated with microbial compositio
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Altering gut bacteria pathways may stimulate fat tissue to prevent obesity

Altering gut bacteria pathways may stimulate fat tissue to prevent obesity | Preventive Medicine | Scoop.it
Cleveland Clinic researchers have uncovered a biological link between gut bacteria metabolism and obesity. The team showed that blocking a specific intestinal microbial pathway can prevent obesity and insulin resistance
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Study finds new link between omega fatty acids and bowel cancer

Study finds new link between omega fatty acids and bowel cancer | Preventive Medicine | Scoop.it
A study by the University of Aberdeen has found that a higher concentration of the molecules that breakdown omega-3 fatty acids is associated with a higher chance of survival from bowel cancer.
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Extra‐virgin olive oil ameliorates cognition and neuropathology of the 3xTg mice: role of autophagy

Extra‐virgin olive oil ameliorates cognition and neuropathology of the 3xTg mice: role of autophagy | Preventive Medicine | Scoop.it
Consumption of extra virgin olive oil (EVOO), a major component of the Mediterranean diet, has been associated with reduced incidence of Alzheimer's disease (AD). However, the mechanisms involved i
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Pre-clinical study suggests Parkinson's could start in gut endocrine cells

Pre-clinical study suggests Parkinson's could start in gut endocrine cells | Preventive Medicine | Scoop.it
Recent research on Parkinson's disease has focused on the gut-brain connection, examining patients' gut bacteria, and even how severing the vagus nerve connecting the stomach and brain might protect some people from the debilitatin
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