Pipettes, Calibration and Metrology
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Pipettes, Calibration and Metrology
Staying up-to-date with pipette business, technology, and regulatory news no longer takes time and effort. TTE scours the Web for the most interesting news for pipette users and the broader scientific & medical communities.
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Top 10 Tips For Running a Greener Lab

Top 10 Tips For Running a Greener Lab | Pipettes, Calibration and Metrology | Scoop.it
Top 10 Tips For Running a Greener Lab read ELGA LabWater news in the SelectScience scientific news archive
TTE Laboratories's insight:

Need some tips on how to make your lab greener? This article from SelectScience has some ideas. 

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Advanced Pipetting with Eppendorf’s New Multipettes Takes the Strain out of Serial Dispensing

Advanced Pipetting with Eppendorf’s New Multipettes Takes the Strain out of Serial Dispensing | Pipettes, Calibration and Metrology | Scoop.it
Advanced Pipetting with Eppendorf’s New Multipettes Takes the Strain out of Serial Dispensing read Eppendorf news in the SelectScience scientific news archive
TTE Laboratories's insight:

Eppendorf has announced new pipettes that focus on ease of use and versatility in the lab. These pipettes offer electric motor driven dispensing to minimize strain and risk of RSI by conveniently positioning buttons to accommodate hand motions.  They also come with an enlarged color display with nine languages for accurate use in different countries. For more information, visit SelectScience to read the full article. 

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How Reliable is Laboratory Testing?

Lab test results play a crucial role in medical decision-making. This article explains the key concepts and practices involved in making laboratory tests reliable.
TTE Laboratories's insight:

Interested in learning more about laboratory testing and the four indicators used to determine reliability of a clinical laboratory test? This article explains accuracy, precision, sensitivity and specificity, and what each term means regarding lab performance. Head on over to labtestsonline to learn more. 

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How to Calibrate Pipettes

Visit our Website: www.pipettes.com Valid calibrations are performed in a controlled lab where well-trained technicians use standardized procedures to obtain...
TTE Laboratories's insight:

Want some virtual "hands-on" learning? Our pipette calibration video has the information you need. Check out our how-to video on Youtube

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Chemistry World Blog » Left-handed in the lab

Chemistry World Blog » Left-handed in the lab | Pipettes, Calibration and Metrology | Scoop.it
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Are you left-handed? Do you have trouble working in the lab? You may find some comfort in this post. 

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Passion for hands-on science lands woman Teacher of the Year

Passion for hands-on science lands woman Teacher of the Year | Pipettes, Calibration and Metrology | Scoop.it
Earlier this school year, Washington County Technical High School Principal Jeff Stouffer was visiting Sally Irwin's biomedical science class and found students dissecting deer hearts.
TTE Laboratories's insight:

This teacher won Teacher of the Year for her passion for hands-on science. This is a great story, and a great example of getting youth excited about learning. We encourage all teachers to share what they know, and actively engage their students in science to get more people involved in the field! 

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World Metrology Day - 20 May 2015

World Metrology Day - 20 May 2015 | Pipettes, Calibration and Metrology | Scoop.it

Metrology plays a central role in enabling the application of light-based technologies, and in turn, light is at the heart of many of the most important new elements of leading-edge measurement technologies.

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Happy World Metrology Day! Here is some information about the day from worldmetrologyday.org.

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Scientist is on a life-saving mission

Scientist is on a life-saving mission | Pipettes, Calibration and Metrology | Scoop.it
In a community where people with master’s degrees are waiting tables for a living, James Powell stands out in the crowd.
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Pipettes can be a part of saving lives!

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State says Breathalyzers are working properly; Northwestern district attorney’s office to continue review of local cases

State says Breathalyzers are working properly; Northwestern district attorney’s office to continue review of local cases | Pipettes, Calibration and Metrology | Scoop.it
NORTHAMPTON — The Northwestern district attorney’s office will continue reviewing local drunken driving cases to ensure any Breathalyzer results to
TTE Laboratories's insight:

Breathalyzers that were not calibrated properly are creating uncertain results.  How certain are you about your pipettes?  Does your provider know how uncertain their measurements actually are?

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Wellcome Image Awards 2015 showcase breathtaking shots of life, death, and science up close

Wellcome Image Awards 2015 showcase breathtaking shots of life, death, and science up close | Pipettes, Calibration and Metrology | Scoop.it
Most wouldn't go looking for magnified cat tongues, sheep stomachs, or parasitoid wasps in a search for gorgeous imagery. But as the finalists for the 2015 Wellcome Image Awards show, these things can be breathtakingly beautiful.


The award showcases the best in science images for the year. "The breath-taking riches of the imagery that science generates are so important in telling stories about research and helping us to understand often abstract concepts," British geneticist, author, and broadcaster Adam Rutherford, one of this year's judges, said in a statement.


"It's not just about imaging the very small either, it's about understanding life, death, sex and disease: the cornerstones of drama and art. Once again, the Wellcome Image Awards celebrate all of this and more with this year’s incredible range of winning images," Rutherford said.


The images are part of the Wellcome Images collections, which are free for non-commercial use and intended to help illustrate scientific concepts and findings.


The winner will be announced at an awards ceremony on March 18. To see previous year's winners, check out Wellcome's Web site. The 20 finalists for 2015 will be showcased at 11 science centers around Britain. Fans of beauty and science in the United States are in luck, too: MIT's Koch Institute and The University of Texas Medical Branch at Galveston will also show off the winners sometime in March.



Via Dr. Stefan Gruenwald
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Biomarker Analysis | Molecular Profiling | Cancer Tumour Biomarkers | Caris life Sciences

Biomarker Analysis | Molecular Profiling | Cancer Tumour Biomarkers | Caris life Sciences | Pipettes, Calibration and Metrology | Scoop.it

Utilising multiple evidence-guided technologies — including IHC, FISH/CISH, PCR and Next-Generation Sequencing (NGS) — Caris Molecular Intelligence provides oncologists with the most relevant, clinically actionable and individualised treatment information to personalise cancer care for all solid tumours. Our suite of tumour profiling services allows the physician to customise the level of profiling they deem necessary for each patient.

 

Caris Molecular Intelligence can be used to inform treatment selection within the standard of care, as well as to reveal treatment alternatives when the standard of care has been exhausted, when there are co-morbidities, or in cases of highly aggressive or rare tumours, metastatic disease or unresectable tumours.

Caris Molecular Intelligence:

Uses a combination of technologies, including Next-Generation Sequencing, to interrogate each tumour at the various biological stages of cancerIs based upon an extensive review of the world’s clinical literature correlating biomarkers to drug responseAssociates therapeutic agents with benefit or lack of benefitMay reveal treatments not previously consideredMay help the physician to identify open enrolling clinical trials based on the patient’s expressed biomarkersProvides all information in one convenient MI Profile™ report


Via Krishan Maggon
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Krishan Maggon 's curator insight, March 28, 2015 12:47 AM

http://www.carislifesciences.eu/

 

Blood-based cancer detection

A revolution in blood-based diagnostics through identification and characterisation of disease-associated circulating microvesicles (cMVs).

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Ebola Whole Virus Vaccine Shown Effective, Safe in Primates

Ebola Whole Virus Vaccine Shown Effective, Safe in Primates | Pipettes, Calibration and Metrology | Scoop.it
An Ebola whole virus vaccine, constructed using a novel experimental platform, has been shown to effectively protect monkeys exposed to the often fatal
TTE Laboratories's insight:

A whole virus vaccine for fighting Ebola in primates has been shown to be effective. Along with being safer, the vaccine likely also offers greater protection than other Ebola vaccines. "It differs from other Ebola vaccines because as an inactivated whole virus vaccine, it primes the host immune system with the full complement of Ebola viral proteins and genes, potentially conferring greater protection." Human trials are next, but are expensive, often costing millions of dollars. Click the link above to read the full article. 

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Study: Cancer drug found to restore memory in mice holds promise as Alzheimer’s treatment

Study: Cancer drug found to restore memory in mice holds promise as Alzheimer’s treatment | Pipettes, Calibration and Metrology | Scoop.it
Study: Cancer drug found to restore memory in mice holds promise as ...
TTE Laboratories's insight:

Saracatinib, a drug used to treat cancer, has been found to help restore memory in mice with cognitive disorders. Researchers at Yale University have been working in collaboration with the National Institutes of Health (NIH), an organization expected to receive a ten percent increase in funding for this research in the coming year.

The drug works by targeting beta amyloid deposits in the brain and lowering their toxic effect on nearby cells. Beta amyloid is often a precursor to Alzheimer's disease. Use of the drug on mice has proven to reverse cognitive problems, including those similar to Alzheimer's. Though optimistic, researchers caution that the effect on humans is still unclear, and further research must be conducted to conclude whether or not the findings can lead to a cure for Alzheimer's. 

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Researchers Debut Table-sized Lab Notebook that Doubles as Work Space

Researchers Debut Table-sized Lab Notebook that Doubles as Work Space | Pipettes, Calibration and Metrology | Scoop.it
Scientists have to clearly document their experiments in a reproducible way, but depending on time pressure and the workflow in the lab, that is often a difficult task. “Merlin,” a digital lab notebook, aims to make scientific documentation easier in the future.
TTE Laboratories's insight:

Do you need some more space in your lab? This "notebook" doubles as a work space, allowing you to keep track of your work as you're doing it. Would you install this new tech in your lab? 

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Daily Pipette Verification Check

For more information or to place an order, visit pipettes.com or call TTE Laboratories at 800.242.6022 While the PLT unit cannot replace regular gravimetric ...
TTE Laboratories's insight:

Between calibration intervals, pipettes can develop leaks from drops, accidents or heavy use. This video demonstrates how to use BrandTech Scientific's tool for detecting leaks in your pipettes. Click here to watch our demonstration video!

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Researchers Grow Breast Tissue In A Lab

Researchers Grow Breast Tissue In A Lab | Pipettes, Calibration and Metrology | Scoop.it
To better understand cancers that grow there
TTE Laboratories's insight:

Researchers in Munich have successfully grown breast tissue in a lab to aid in cancer research. Specifically, these scientists have grown mammary glands: tissue where most types of breast cancer occur. The hope for this research is to develop new treatments by further understanding how cancer develops in this tissue. As researcher Christina Scheel puts it, "if you want to repair a broken car, you have to know how it works. Breast cancer is essentially out-of-control development." Hopefully, by researching the mammary glands, a more effective treatment for breast cancer will follow soon.


You can read the full article here

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For the first time, scientists create a lab-grown limb

For the first time, scientists create a lab-grown limb | Pipettes, Calibration and Metrology | Scoop.it
A team of researchers at Massachusetts General Hospital has grown a rat limb in a lab -- paving the way forward for bioengineered human transplants.
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Researchers at Massachusetts General Hospital have successfully created a lab-grown limb of a rat with functioning vascular and muscle tissue. The first of its kind, this new development may soon allow for human limb transplant surgery using a patient's own biological material.


Limbs have previously been difficult to replicate in such a manner due to the complexity that comes from containing multiple tissue types. According to Harald Ott, MD, of the MGH Department of Surgery and the Center for Regenerative Medicine, "limbs contain muscles, bone, cartilage, blood vessels, tendons, ligaments and nerves -- each of which has to be rebuilt and requires a specific supporting structure called the matrix...We have shown that we can maintain the matrix of all of these tissues in their natural relationships to each other, that we can culture the entire construct over prolonged periods of time, and that we can repopulate the vascular system and musculature" with these lab-grown limbs. 


The next steps include replicating this process in muscle regeneration with human cells, then continuing with bone, cartilage and connective tissue. For more, click here to read the full story from CNET.

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New focus on rape kit tests could put thousands behind bars

New focus on rape kit tests could put thousands behind bars | Pipettes, Calibration and Metrology | Scoop.it
The evidence piled up for years, abandoned in police property rooms, warehouses and crime labs. Now, tens of thousands of sexual assault kits are giving up their secrets — and rapists who've long remained free may finally face justice. A...
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For years, rape kit tests have been piling up in police warehouses and crime labs. Countless suspects have remained free due to a lack of funding, and thus a lack of testing. However, a new focus on rape kit tests is likely to bring about a change. Test kits dating back tens of years may finally be able to produce results, indicting suspects that have walked free for far too long. The coming years may see thousands of criminals face justice thanks to this new focus and new funding. 

To read the full story, click here

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You could soon be taking a robot pill that uses sugar needles

You could soon be taking a robot pill that uses sugar needles | Pipettes, Calibration and Metrology | Scoop.it
Swiss pharmaceutical company Novartis has announced a collaboration with US-based biotech startup Rani Therapeutics to create a “robotic pill” that can deliver complex drugs which would usually be given with injections. The…
TTE Laboratories's insight:

A Swiss pharmaceutical company has partnered with a US biotech startup to develop a robotic pill that replaces vaccines by using sugar needles to directly deliver medicine. The new pill would be taken like a normal pill, but tiny needles would deliver the medicine directly into the intestine. Studies will continue over the next two years, but the companies hope to make the pill a reality soon. 

Click here to read the full story. 

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U.S. Introduces New DNA Standard for Ensuring Accuracy of Genetic Tests

U.S. Introduces New DNA Standard for Ensuring Accuracy of Genetic Tests | Pipettes, Calibration and Metrology | Scoop.it
By offering a new DNA standard for tests used in the diagnosis and treatment of disease, the federal government is opening a new era in genetic medicine.
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FDA’s Role in the Drug Approval Process

FDA’s Role in the Drug Approval Process | Pipettes, Calibration and Metrology | Scoop.it
The U.S. Food and Drug Administration (FDA) examines, tests, and approves a wide range of items for medical use, including drugs, medical devices, food, cosmetics and many other health-related products.

Via Krishan Maggon
TTE Laboratories's insight:

The FDA plays an important role in protecting consumers from drugs that may be harmful, or simply not effective. Without proper regulation, pharmaceutical companies would not be held accountable for fraudulent claims regarding new drugs being brought to market. This article covers the process a drug must go through before being accepted by the FDA. The steps a drug must complete are drug development, animal testing, submittal of an Investigational New Drug application, clinical trials, submittal of a New Drug Application, drug labeling, facility inspection, and finally, drug approval. Prescription and over-the-counter drugs must both be approved by the FDA in similar fashions. For more details regarding this process, click the link to the full article from HealthyChildren.org

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ISO 8655 Calibration Standards | What is ISO 8655 & FAQ's

ISO 8655 Calibration Standards | What is ISO 8655 & FAQ's | Pipettes, Calibration and Metrology | Scoop.it
ISO 8655 compliance ensures the highest competency and reliability for liquid handling. Learn about ISO/IEC 17025:2005 instrument calibration.

http://www.ttelaboratories.com/tte-university/iso-8655


Via SandraEllis
TTE Laboratories's insight:

We stumbled across our own article on someone else's news feed! Thank you!

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How BARDA Is Helping Speed Up Drug Development/Manufacture - Life Science Leader Magazine

How BARDA Is Helping Speed Up Drug Development/Manufacture - Life Science Leader Magazine | Pipettes, Calibration and Metrology | Scoop.it

An unusual federal government agency, the Biomedical Advanced Research and Development Authority (BARDA), is providing $ 2 billion of funding and technical and technical expertise to more than 85 pharmaceutical and biotech companies and 25 academic organizations.


The goal is to accelerate the late-stage development and manufacture of vaccines, drugs, diagnostics, and medical devices that could prove vital to protecting public health during an anthrax outbreak, a bioterrorist nuclear event, pandemic H7N9 (avian flu) epidemic, or an emerging infectious disease that is antibiotic-resistant.

 

BARDA, with a 2014-2015 budget totaling more than $2 billion, helps underwrite the advanced development and production of therapies for injuries resulting from chemical, biological, radiological, and nuclear (CBRN) accidents and bioterrorist attacks. The design, development, manufacture, clinical testing, and stockpiling of pandemic H5N1 and H7N9 vaccines and a new class of broad-spectrum antimicrobial drugs against multidrugresistant “superbugs” also are supported by the agency. BARDA was created by the Pandemic and All-Hazards Preparedness Act of Congress in 2006 to help safeguard the U.S. population from deadly humanmade and naturally occurring threats that are not widely addressed by industry.


BARDA’s portfolio of MCMs targeting Ebola includes ZMapp, the experimental drug cocktail of three monoclonal antibodies that came to the world’s attention in August 2014 when several health workers in Liberia and the U.S. became infected with the deadly virus and were treated with the drug under the FDA’s compassionate use program. ZMapp’s monoclonal antibodies are produced in a time-consuming process in tobacco plants at Kentucky Bioprocessing. In September 2014, ZMapp’s developer, Mapp BioPharmaceutical, signed a multiyear contract with BARDA with a base value of $24.9 million to support latestage development and manufacturing of the drug cocktail. In early March 2015, clinical trials of ZMapp began in Liberia. If ZMapp proves safe and effective in clinical trials, hundreds of doses of the drug could be manufactured for wide distribution by the end of 2015.


 Emergent BioSolutions has been a BARDA partner since 2007. BARDA funding enables Emergent to manage the agency’s CIADM in Maryland and manufacture millions of doses of BioThrax for the nation’s stockpile. When the company’s new Lansing, MI manufacturing facility is approved by the FDA, Emergent should be able to boost its annual BioThrax production to 20 to 25 million doses from the 7 to 9 million doses now being manufactured. BARDA also is funding Emergent’s evaluation of BioThrax’s effectiveness as a postexposure prophylaxis, as well as three new experimental anthrax products under development at the company.



Via Krishan Maggon
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Krishan Maggon 's curator insight, March 31, 2015 8:43 AM

The FDA has approved 20 BARDA funded products mostly for pandemic influenza. 

 

Since opening its offices at the U.S. Department of Health and Human Services (HHS) in 2007, BARDA has supported the development and the manufacture or purchase of more than 160 vaccines and therapeutics. BARDA refers to the products in its portfolio as medical countermeasures (MCMs).

 

The agency has supplied the federal government’s Strategic National Stockpile with more than 10 novel MCMs, including anthrax and botulinum antitoxins, which were licensed by the FDA under the Animal Efficacy Rule. In addition to MCMs for smallpox, anthrax, botulism, and pandemic influenza, BARDA’s portfolio includes vaccines and drugs for other viral hemorrhagic diseases such as Ebola and Marburg.

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Perceptron Offers Latest Enterprise 3D Scanning Metrology Systems

Perceptron Offers Latest Enterprise 3D Scanning Metrology Systems | Pipettes, Calibration and Metrology | Scoop.it
Metrology is the science of measurement, and it includes all theoretical and practical aspects of measurement. Enterprise metrology sensors and software col

Via Brittney
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Brittney's curator insight, April 7, 2015 5:55 AM

Perceptron Offers Latest Enterprise 3D Scanning Metrology Systems http://3dprint.com/56254/perceptron-metrology-3d-scan/

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Metrology dept move to help people strike gold, literally

Metrology dept move to help people strike gold, literally | Pipettes, Calibration and Metrology | Scoop.it
Metrology dept move to help people strike gold, literally - A recent move made by Legal Metrology Department will certainly bring smiles on the face of people seeking gold loan or selling gold.
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Accuracy is key, and can earn you extra money!

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