Pediatric Medicine
2 views | +0 today
Follow
Your new post is loading...
Your new post is loading...
Scooped by Pediatric Team
Scoop.it!

Protein Linked to Atopic Dermatitis - NIH Research Matters - National Institutes of Health (NIH)

Protein Linked to Atopic Dermatitis - NIH Research Matters - National Institutes of Health (NIH) | Pediatric Medicine | Scoop.it
A study in mice suggests that lack of a certain protein may trigger atopic dermatitis, the most common type of eczema. The finding may lead to improved treatment options for people.
more...
No comment yet.
Scooped by Pediatric Team
Scoop.it!

ADHD makes you different, not defective - CNN

ADHD makes you different, not defective - CNN | Pediatric Medicine | Scoop.it
ADHD makes you different, not defective
CNN
Los Angeles (CNN) -- A few days ago, I received an Instagram message from a young girl who has attention deficit hyperactivity disorder. She was struggling in school and depressed since being diagnosed.
more...
No comment yet.
Scooped by Pediatric Team
Scoop.it!

9 Tips to Deal with Forgetfulness in ADHD - PsychCentral.com (blog)

9 Tips to Deal with Forgetfulness in ADHD - PsychCentral.com (blog) | Pediatric Medicine | Scoop.it
9 Tips to Deal with Forgetfulness in ADHD
PsychCentral.com (blog)
Forgetfulness is a symptom that “can impact everything” for adults with attention deficit hyperactivity disorder (ADHD), said Mindy Schwartz Katz, MS, ACC.
more...
No comment yet.
Scooped by Pediatric Team
Scoop.it!

Petition calls for shorter wait lists for children - Newfoundland and Labrador Compass

Petition calls for shorter wait lists for children - Newfoundland and Labrador Compass | Pediatric Medicine | Scoop.it
Petition calls for shorter wait lists for children Newfoundland and Labrador Compass Darlene Brown said the behavioural therapist she consulted believes her son is showing signs of attention deficit hyperactivity disorder, sensory problems, anxiety...
more...
No comment yet.
Rescooped by Pediatric Team from Forever Living Aloe Vera Products In Pakistan
Scoop.it!

ALLERGIC DERMATITIS

ALLERGIC DERMATITIS | Pediatric Medicine | Scoop.it
ALLERGIC DERMATITIS Allergic dermatitis is a reaction of the skin to certain substances, plant or products. Often it is confused with nervous dermatitis which is caused by nervousness, stress etc. ...

Via Muhammad Nasir
more...
Muhammad Nasir's curator insight, February 19, 2013 2:38 PM

ALLERGIC DERMATITIS

Scooped by Pediatric Team
Scoop.it!

Too Much TV, Too Little Sleep - dailyRx

Too Much TV, Too Little Sleep - dailyRx | Pediatric Medicine | Scoop.it
Medical Daily
Too Much TV, Too Little Sleep
dailyRx
The more TV the children watched, the less sleep they got, even after considering any attention deficit hyperactivity disorder symptoms in the children and their levels of physical activity.
more...
No comment yet.
Scooped by Pediatric Team
Scoop.it!

Early-Onset Atopic Dermatitis - National Eczema Association

Early-Onset Atopic Dermatitis - National Eczema Association | Pediatric Medicine | Scoop.it
Atopic dermatitis (AD) often manifests in early childhood and has variable disease course among individual patients. Previous studies regarding the natural course of AD have usually been of small sample size and were not ...
more...
No comment yet.
Scooped by Pediatric Team
Scoop.it!

Distribution of Malassezia species on the skin of patients with atopic ... - 7thSpace Interactive (press release)

Distribution of Malassezia species on the skin of patients with atopic ...
more...
No comment yet.
Rescooped by Pediatric Team from Of human kindness
Scoop.it!

Histamine H4 Receptor Antagonists - Journal Watch Dermatology

Histamine H4 Receptor Antagonists

 

In a mouse model of allergic contact dermatitis, an H4 receptor antagonist produced encouraging results.

The histamine receptors H1 and H2 (antagonized by H1 antihistamines, such as diphenhydramine, and by H2 antihistamines, such as cimetidine) are well known. Investigators recently discovered additional, unique histamine receptors H3 and H4. H3 receptors reside mostly on neurons, so antagonists to these receptors could treat cognitive impairment, schizophrenia, sleep/wake disorders, epilepsy, and neuropathic pain. H4 receptors reside mostly on hemopoietic cells, and thus their antagonists might treat inflammatory diseases and pruritus. Blockade of H4 receptors obstructs histamine-induced chemotaxis of eosinophils and mast cells. A potential H4 antagonist drug is currently being tested in a phase II clinical trial.

In a recent study in mice with allergic contact dermatitis elicited by dinitrochlorobenzene, the H4 receptor antagonist JNJ7777120 ameliorated dermatitis, decreasing epidermal thickness and numbers of both mast cells and eosinophils. Before JNJ7777120 treatment, levels of immunoglobulin E were increased in serum in these mice, and levels of interleukin (IL)-4, IL-5, and IL-6 (Th2 cytokines); interferon-; and L-12 were increased in dermatitic skin. Treatment with the H4 antagonist decreased these levels. Adding the H1 receptor antagonist olopatadine provided additional effects.

 

Comment: This article suggests we take a "heads-up" interest in further studies of H4 antagonists in dermatology. The ability to ameliorate allergic contact dermatitis with a safe pill has obvious appeal.


Via David Lewis
more...
No comment yet.