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Removing spurious interactions in complex networks

Removing spurious interactions in complex networks | Papers | Scoop.it

Identifying and removing spurious links in complex networks is meaningful for many real applications and is crucial for improving the reliability of network data, which, in turn, can lead to a better understanding of the highly interconnected nature of various social, biological, and communication systems. In this paper, we study the features of different simple spurious link elimination methods, revealing that they may lead to the distortion of networks’ structural and dynamical properties. Accordingly, we propose a hybrid method that combines similarity-based index and edge-betweenness centrality. We show that our method can effectively eliminate the spurious interactions while leaving the network connected and preserving the network's functionalities.

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Using Protein Interaction Networks to Understand Complex Diseases

Recent developments in biotechnology have enabled interrogation of the cell at various levels, leading to many types of "omic" data that provide valuable information on multiple genetic and environmental factors and their interactions. The featured Web extra is a video interview with Mehmet Koyutürk of Case Western Reserve about how biotechnology can track genetic markers to advance cancer research.

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