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Organic Farming, Genetics and the future of food
sustainable agriculture, farming and plant genetics
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PNAS: Retargeting of the Bacillus thuringiensis toxin Cyt2Aa against hemipteran insect pests (2013)

PNAS: Retargeting of the Bacillus thuringiensis toxin Cyt2Aa against hemipteran insect pests (2013) | Organic Farming, Genetics and the future of food | Scoop.it

Although transgenic crops expressing Bacillus thuringiensis (Bt) toxins have been used successfully for management of lepidopteran and coleopteran pest species, the sap-sucking insects (Hemiptera) are not particularly susceptible to Bt toxins. To overcome this limitation, we demonstrate that addition of a short peptide sequence selected for binding to the gut of the targeted pest species serves to increase toxicity against said pest. Insertion of a 12-aa pea aphid gut-binding peptide by adding to or replacing amino acids in one of three loops of the Bt cytolytic toxin, Cyt2Aa, resulted in enhanced binding and toxicity against both the pea aphid, Acyrthosiphon pisum, and the green peach aphid, Myzus persicae. This strategy may allow for transgenic plant-mediated suppression of other hemipteran pests, which include some of the most important pests of global agriculture.


Via Kamoun Lab @ TSL
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Was the global food crisis really a crisis? | International Food Policy Research Institute (IFPRI)

Was the global food crisis really a crisis? | International Food Policy Research Institute (IFPRI) | Organic Farming, Genetics and the future of food | Scoop.it
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Scientists find genes to tackle climate change in outback rice - UQ News Online - The University of Queensland

Scientists find genes to tackle climate change in outback rice - UQ News Online - The University of Queensland | Organic Farming, Genetics and the future of food | Scoop.it
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