Organ Donation & Transplant Matters Resources
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Organ Donation & Transplant Matters Resources
Combining reports, research findings and topic reviews
Curated by Deborah Verran
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New Stanford blood test identifies heart-transplant rejection earlier than conventional biopsy - Stanford Medical Center Report

New Stanford blood test identifies heart-transplant rejection earlier than conventional biopsy - Stanford Medical Center Report | Organ Donation & Transplant Matters Resources | Scoop.it

Reported online via the Stanford Medical Center Report the news that
a blood test can identify heart-transplant rejection at an earlier stage than a conventional biopsy (as pictured).

 

The test detects of circulating donor DNA in the blood of heart transplant recipients. As this is a preliminary report more experience needs to be gained with this test prior to it becoming a possible addition to the current laboratory testing that is used to help monitor transplant recipients.

Deborah Verran's insight:

The next phase in the investigation of 'biomarkers' that will assist in the management of heart transplant recipients

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Life, Death and the Organ Allocation System - Lawfuel

Life, Death and the Organ Allocation System - Lawfuel | Organ Donation & Transplant Matters Resources | Scoop.it

This opinion piece posted online under the title "Life, Death and the Organ Allocation System" is written by a lawyer in the United States.

 

On the one-year anniversary of the Sarah Murnaghan lung allocation case, Philadelphia litigator Steve Harvey writes about about the case as well as the factors behind the ongoing critical shortage of organs within the United States.

Deborah Verran's insight:

Thoughtful, well written and of interest to professionals involved in organ donation

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Barriers To Knowledge Sharing

Barriers To Knowledge Sharing | Organ Donation & Transplant Matters Resources | Scoop.it

Knowledge sharing is the corner-stone of many organisations’ knowledge-management (KM) strategy. Despite the growing significance of knowledge sharing’s practices for organisations’ competitiveness and market performance, several barriers make it difficult for KM to achieve the goals and deliver a positive return on investment.

 


Via Kenneth Mikkelsen
Deborah Verran's insight:

The barriers to KS can occur at the level of the individuals, within organizations or between organizations. This article elegantly outlines how and why these barriers may exist.

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Ignasi Alcalde's curator insight, May 26, 2014 4:16 AM

Knowledge Management basics and barriers

 

 

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What Makes a Good Chairman?

What Makes a Good Chairman? | Organ Donation & Transplant Matters Resources | Scoop.it

What are the qualities of strong board chairs? This online posting provides an outline on what are currently perceived to be the important qualities (& skill sets) of board chairs. This incldues leadership and doing the 'right thing'.

 

http://t.co/1355cnIJvI


Deborah Verran's insight:

This article will be of interest to healthcare professionals who hold leadership roles and have governance responsibilities

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Transplant patient wins payout over kidney from donor with cancer

Transplant patient wins payout over kidney from donor with cancer | Organ Donation & Transplant Matters Resources | Scoop.it

Reported via The Guardian in the United Kingdom that Robert Law (pictured) aged, 62, had to undergo six cycles of chemotherapy after receiving a kidney from woman who had lymphoma http://t.co/EKEVGfRdug)...

 

More background information on the case can be found by clicking on the link

Deborah Verran's insight:

Comprehensive processes are required in organ donation systems to prevent the overlooking of critical information which can then lead to adverse consequences

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Mechanism helps explain persistence of hepatitis C virus but new treatments on the horizon

Mechanism helps explain persistence of hepatitis C virus but new treatments on the horizon | Organ Donation & Transplant Matters Resources | Scoop.it

The first part of this post is the news that researchers at the University of California, San Diego School of Medicine have identified a mechanism that explains why people with the hepatitis C virus get liver disease. Plus this may be why the virus is able to evade the normal mechanisms in the body that eradicate similar viral pathogens. For more on this story click

on the banner headline.

 

The second part is news on some of the new antiviral combinations which appear promising for the treatment of hepatitis C. For more on this click on either of the following links-

 

http://www.medicalnewstoday.com/releases/275472.php#.U057niNk8H8.twitter

 

http://www.medicalnewstoday.com/releases/275468.php

 

 

 

Deborah Verran's insight:

With hepatitis C being the most common indication for liver transplantation in many countries, any progress in either the understanding of how the virus causes liver disease or in treating this virus is extremely important

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ISHLT Announces Latest Results of both the NOVEL and the INSPIRE Lung Trials of EVLP

ISHLT Announces Latest Results of both the NOVEL and the INSPIRE Lung Trials of EVLP | Organ Donation & Transplant Matters Resources | Scoop.it

Two clinical research updates have been announced at the 2014 ISHLT meeting. Both involve the use of ex-vivo lung preservation technology. The Results of the NOVEL Lung Trial Show Great Promise at this stage and more info can be obtained by clicking on the banner headline.

 

The results of the INSPIRE Lung Trial can be accessed by clicking on the following link-

http://www.prweb.com/releases/2014/04/prweb11720765.htm

 

Deborah Verran's insight:

Early stages of understanding the place of ex-vivo lung preservation as an option for both managing and evaluating deceased donor lungs prior to transplantation

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Social Media & Healthcare: Improve Service and Expand Reach

Innovative uses of social media to support health care service, marketing, and outreach. Slides from social media panel at educational event sponsored by Nat...

Via Plus91
Deborah Verran's insight:

A slideshow providing interesting statistics as well as examples of how US hospitals are engaging in social media, including the positives and negatives

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'Change rules on baby organ donors' - MSN UK

'Change rules on baby organ donors' - MSN UK | Organ Donation & Transplant Matters Resources | Scoop.it

The results of a study published online in a medical journal have led experts to call for a 'Change to the rules on small baby organ donors' within the United Kingdom (UK). Because of the current limitation on the lower age limit for small paediatric organ donors, in the  UK a baby in need of a life saving heart donation - where only small newborn hearts are suitable for transplant - often needs to wait until a donor organ is flown in from somewhere else.

 

To read more about the research behind this story click on the banner headline. For the press release from the hospital where this research was undertaken (Great Ormond Street in London) click on the following link-

 

http://www.gosh.nhs.uk/news/press-releases/2014-press-release-archive/great-ormond-street-hospital-study-highlights-untapped-potential-of-newborn-organ-donation-in-the-uk/

 

Deborah Verran's insight:

Important research which may lead to changes being made to the current rules for peadiatric organ donation within the United Kingdom

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Global Observatory on Donation & Transplantation (GODT)

Global Observatory on Donation & Transplantation (GODT) | Organ Donation & Transplant Matters Resources | Scoop.it

Overseen by the World Health Organization and ONT in Spain is the Global Observatory on Donation and Transplantation.

 

For data on global organ donation rates as well as as the rates of solid organ transplantation click on the banner headline. To access slides from the most recent annual report click on the graphic (pictured) on the GODT home page

Deborah Verran's insight:

Accurate, reliable data presented via graphics which allow for a ready comparison of both the rates of organ donation and organ transplantation

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The Ethics Of Solving The Transplant Organ Shortage

The Ethics Of Solving The Transplant Organ Shortage | Organ Donation & Transplant Matters Resources | Scoop.it

At the 2014 AAAS meeting in Chicago, medical ethicist Mark Siegler laid out a framework for a potentially provocative solution to the shortage of kidneys available for transplantation.

 

His recommendations all pertain to enhancing live kidney donation as a means of increasing the number of kidney transplants that can be performed, particularly within the United States.

Deborah Verran's insight:

In order to optimise the number of live donor kidney transplants that are able to be undertaken within any country it is important to examine where barriers may exist

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Microrobotic technique combines 3D printing and tissue engineering

Microrobotic technique combines 3D printing and tissue engineering | Organ Donation & Transplant Matters Resources | Scoop.it

Researchers at Brigham and Women's Hospital (BWH) and Carnegie Mellon University have introduced a unique micro-robotic technique to assemble the components of complex materials, the foundation of tissue engineering and 3D printing, described in the Jan. 28, 2014, issue of Nature Communications ("Untethered micro-robotic coding of three-dimensional material composition").

 

The presented approach uses untethered magnetic micro-robotic coding for precise construction of individual cell-encapsulating hydrogels (such as cell blocks). The micro-robot, which is remotely controlled by magnetic fields, can move one hydrogel at a time to build structures. This is critical in tissue engineering, as human tissue architecture is complex, with different types of cells at various levels and locations. When building these structures, the location of the cells is significant in that it will impact how the structure will ultimately function. "Compared with earlier techniques, this technology enables true control over bottom-up tissue engineering," explains Tasoglu.

 

Tasoglu and Demirci also demonstrated that micro-robotic construction of cell-encapsulating hydrogels can be performed without affecting cell vitality and proliferation. Further benefits may be realized by using numerous micro-robots together in bioprinting, the creation of a design that can be utilized by a bioprinter to generate tissue and other complex materials in the laboratory environment."

 

 


Via Dr. Stefan Gruenwald
Deborah Verran's insight:

Another interesting step in the research that is being performed in the tissue engineering sphere. However there is a lot more research required before bioengineered tissues can be used for transplantation into humans

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Sieg Holle's curator insight, February 16, 2014 11:23 AM

Towards our age of abundance and self sufficiency and personal choice?

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Long-term Survival Possible for Pediatric Heart Transplant Patients - Newswise (press release)

Long-term Survival Possible for Pediatric Heart Transplant Patients - Newswise (press release) | Organ Donation & Transplant Matters Resources | Scoop.it

Via the Society of Thoracic Surgeons comes these two press releases on the long term outcomes of heart transplantation. 

 

In one study Hannah Copeland, MD and colleagues from Loma Linda University in Loma Linda, CA, reviewed the medical charts of 337 pediatric heart transplant recipients. To read more click on the banner headline.

 

The second press release on the long term outcomes of adult heart transplant recipients can be viewed by clicking on the following link-

http://www.newswise.com/articles/heart-transplant-success-improving-patients-living-longer?ret=/articles/list&category=medicine&page=1&search%5Bstatus%5D=3&search%5Bsort%5D=date+desc&search%5Bsection%5D=10&search%5Bhas_multimedia%5D=

 

Deborah Verran's insight:

The outcomes following heart transplantation continue to improve with many patients now surviving up to 20 years following the procedure.

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Flock Associates - Recife Sport club: Immortal Fans. Integrated Marketing by Ogilvy Brazil - YouTube

A report via Brazil which will resonate with soccer fans around the world as the Soccer World cup begins. This story was initially  reported online via http://www.flock-associates.com

 

Taking advantage of the strong bond and enormous pride that Recife fans felt towards their soccer team, Ogilvy & Mather Brazil engineered a campaign to encourage the fans to sign up to be organ donors

 

The results have been amazing and are a testament to the power of passion for a sport translating into a benefit for the community as outlined in this short YouTube video

Deborah Verran's insight:

Soccer fans in Brazil are not only passionate about their sport but in the case of one club are passionate about organ donation as well

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Organ donation infographic & event - BAME communities

Organ donation infographic & event - BAME communities | Organ Donation & Transplant Matters Resources | Scoop.it

As a result of outreach activities held in the United Kingdom the data that have been obtained have been analysed and converted into an infographic.

 

This organ donation infographic summarises the key insights for theawareness and support for organ donation amongst Black, Asian and Minority Ethnic (BAME) communities.

 

For more information, click on the banner headline.

Deborah Verran's insight:

Interesting data from the United Kingdom on the levels of knowledge and awareness in the BAME communities

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Kidney transplant patients live longer than those in intensive home hemodialysis - Medical Xpress

Kidney transplant patients live longer than those in intensive home hemodialysis - Medical Xpress | Organ Donation & Transplant Matters Resources | Scoop.it

Analysis of data from a research study performed in Canada has revealed that Kidney transplant patients live longer than those receiving intensive home hemodialysis.

 

A first-ever study from a large Canadian centre has found that kidney

transplant recipients lived longer and had better treatment success regardless of what type of donor kidney that they received. 'Kidney transplant is still the best treatment option says Dr Chris Chan (pictured) who is a nephrologist at the Toronto General Hospital.

 

To read more about the findings of this study, click on the banner headline.

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How best to encourage organ donation: Research brief - Journalist's Resource

How best to encourage organ donation: Research brief - Journalist's Resource | Organ Donation & Transplant Matters Resources | Scoop.it

From the Journalist's Resource web site of the Harvard Kennedy School, Sorenstein Centre on Media, Politics and Public Policy comes this article titled: How best to encourage organ donation.

 

The Research brief Journalist's Resource Physicians have taken up this cause as well, along with recent editorials in the Clinical Journal of the American Society of Nephrology and Medscape. It is apparent that even if the potential of the deceased donor organ donation pool was fully realized within the United States, that there would still be a gap in the numbers of people  awaiting kidney transplantation and the number of available donor organs.

 

Hence the additional importance of live kidney donation and why this particular article contains the conclusion that other measures now need to be adopted within the United States.

Deborah Verran's insight:

Interesting article out of the United States

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An About-Face on a Risky Transplant - New York Times

An About-Face on a Risky Transplant - New York Times | Organ Donation & Transplant Matters Resources | Scoop.it

An About-Face on a Risky Transplant. This report outlines in detail how medical professionals have now come to accept that face transplantation has a place in the management of patients who have sustained severe disfiguring facial trauma. It is accompanied by a series of detailed graphics which can be accessed by clicking on the banner headline.

When patient Richard Lee Norris, 37, received a full face transplant in 2012, years after a gun accident destroyed his chin, lips, teeth and nose. Doctors gave him a new jaw, teeth, tongue, skin and muscles.

Deborah Verran's insight:

Progress is being made with the understanding of how face transplantation has a role in the management of selected patients

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Traits of a Motivated Leader

Traits of a Motivated Leader | Organ Donation & Transplant Matters Resources | Scoop.it
If there is one trait that virtually all effective leaders have, it is motivation – a variety of self-management whereby we mobilize our positive emotions to drive us toward our goals. Motivated leaders are driven to achieve beyond expectations – their own and everyone else’s. The key word here is achieve.

Via David Hain
Deborah Verran's insight:

This article will be of interest to professionals who hold leadership roles and/ or responsibilities

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David Hain's curator insight, April 14, 2014 3:35 AM

Goleman on the importance of intrinsic #motivation for #leaders.

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Proceed II International Heart Transplant Trial Results Revealed at ISHLT 34th ... - PR Web (press release)

Proceed II International Heart Transplant Trial Results Revealed at ISHLT 34th ... - PR Web (press release) | Organ Donation & Transplant Matters Resources | Scoop.it

The Proceed II International Heart Transplant Trial Results are being Revealed at the ISHLT 34th meeting.

 

Preliminary outcome data are favorable for heart transplant outcomes where donor hearts were maintained on the TransMedics Organ Care System device compared to being placed into conventional cold storage prior to transplantation.

 

Further comments from medical professionals on this new technology can be viewed via this link-

http://www.inquisitr.com/1207466/transporting-a-heart-in-a-box-is-a-great-advance-says-dr-mark-plunkett/

 

Deborah Verran's insight:

Promising preliminary results with the use of ex-vivo normothermic heart preservation

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FDA Panel Favors Device to Boost Lung Transplant Success - MedPage Today

FDA Panel Favors Device to Boost Lung Transplant Success - MedPage Today | Organ Donation & Transplant Matters Resources | Scoop.it

The news has come that an FDA Panel has given the approval for a normothermic lung preservation device to continue to be used in clinical research in order to boost lung transplant success as reported via MedPage Today.

 

A Canadian center involved in the HELP trial increased the proportion of donated lungs actually transplanted from 25% to 36% after starting to use the EXVIVO lung perfusion device. Of note there remains limited data for the medium to long term outcomes of lungs that have been transplanted after being preserved using this particular device. 

Deborah Verran's insight:

News that the EXVIVO lung preservation device has  received a preliminary limited approval by the FDA in the United States (humanitarian use device exemption)

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Muslim Beliefs May Sway Attitudes Concerning Organ Donation - PsychCentral.com

Muslim Beliefs May Sway Attitudes Concerning Organ Donation - PsychCentral.com | Organ Donation & Transplant Matters Resources | Scoop.it

This online report of research conducted in the United States concludes that muslim beliefs may sway attitudes of some members of the community when it comes to Organ Donation.

 

American Muslims who view negative events as punishment from God are more likely to think that organ donation is unethical.

 

This study highlights the complex interplay that exists between religious beliefs and community attitudes when it comes to decision making around organ donation.

 

Deborah Verran's insight:

Important findings of relevance to healthcare professionals involved with organ donation

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New Organ Procurement Approach May Benefit Transplants - Supply & Demand Chain Executive

New Organ Procurement Approach May Benefit Transplants - Supply & Demand Chain Executive | Organ Donation & Transplant Matters Resources | Scoop.it

This report of a new organ donor management approach which may be beneficial particularly for liver transplant purposes comes from the United States. What it reveals is that centralisation of organ retrieval services potentially is cost effective.

As donor organs have a finite shelf life (ie a limited time that can be spent in cold storage — livers 6 to 10 hours following retrieval from the donor; hearts and lungs even less, kidneys less than 24 hours), measures which can increase the number of organs for transplantation are also important.

 

To read more on this story click on the following link (the sdcexec link is not available free online)-

http://o.canada.com/health/transplant-study-shows-benefits-of-a-single-organ-donation-centre/

 

Deborah Verran's insight:

This development will be watched closely and with interest. Whether it remains more cost effective to transfer potential organ donors to a fully resourced central facility or not, remains to be seen in many regions around the world.

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Infographic: Where Will mHealth Be in 2024?

Infographic: Where Will mHealth Be in 2024? | Organ Donation & Transplant Matters Resources | Scoop.it

Ten years ago, mHealth as we presently know it didn’t exist. But ten years from now, its sophistication and utility may be far greater than anything we can presently envision.


Via Emmanuel Capitaine , Lionel Reichardt / le Pharmageek
Deborah Verran's insight:

A glimpse at the future of mobile technology which will be game changing in many areas including healthcare

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The 1% Rule in Four Digital Health Social Networks: An Observational Study

The 1% Rule in Four Digital Health Social Networks: An Observational Study | Organ Donation & Transplant Matters Resources | Scoop.it

This is the title of a research study reported online via the Journal of Medical Internet Research: The 1% Rule in Four Digital Health Social Networks: An Observational Study

 

Statistics indicate that 90% of the users of the networks in question are lurkers, 9% may interact online and just 1% are responsible for the majority of the content.

 

 


Via Denise Silber
Deborah Verran's insight:

Important result for organizations who are moving into establishing and maintaining online networks in the healthcare sector

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ChemaCepeda's curator insight, February 4, 2014 7:13 PM

La regla del 99% en comunidades virtuales se cumple también en las de salud

Carlo V Caballero-Uribe MD's curator insight, February 4, 2014 8:56 PM

Muy interesante estudio. De las personas que contribuyen en social media , el 1% son los superusuarios que generan la mayor cantidad de contenido y agregan valor, 9% contribuyen ocasionalmente y 90% son solo observadores.tener superususuarios en las comunidades para reclutar y retener es fundamental para el exito a largo plazo. 

Los observadores pueden beneficiarse pero terminan generando poco valor a la red. 

Los que aportan  parecen ser las clave de estás comunidades.

Alejandro Melo-Florián MD's curator insight, February 5, 2014 9:39 PM

Es como la ley de Vilfredo Pareto....