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'Change rules on baby organ donors' - MSN UK

'Change rules on baby organ donors' - MSN UK | Organ Donation & Transplant Matters Resources | Scoop.it

The results of a study published online in a medical journal have led experts to call for a 'Change to the rules on small baby organ donors' within the United Kingdom (UK). Because of the current limitation on the lower age limit for small paediatric organ donors, in the  UK a baby in need of a life saving heart donation - where only small newborn hearts are suitable for transplant - often needs to wait until a donor organ is flown in from somewhere else.

 

To read more about the research behind this story click on the banner headline. For the press release from the hospital where this research was undertaken (Great Ormond Street in London) click on the following link-

 

http://www.gosh.nhs.uk/news/press-releases/2014-press-release-archive/great-ormond-street-hospital-study-highlights-untapped-potential-of-newborn-organ-donation-in-the-uk/

 

Deborah Verran's insight:

Important research which may lead to changes being made to the current rules for peadiatric organ donation within the United Kingdom

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Tissue engineering: Organs from the lab - Nature.com

Tissue engineering: Organs from the lab - Nature.com | Organ Donation & Transplant Matters Resources | Scoop.it

The body's organs are more complex than any factory. Attempts to mirror their physiology in the laboratory are now getting closer to capturing their individual intricacies.

 

This well written article outlines the gains that have been made with organ and tissue engineering, particularly the "organ on a chip" technology which is now increasingly being used for research and testing purposes.

 

However due to the inherent complexities in all of the human organs there is still a lot more in the way of research which needs to be undertaken. This is in order to allow step wise progress in the bioengineering of organs to be made.

Deborah Verran's insight:

The latest summary of this fascinating area of ongoing research.

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Surgeon describes first skull and scalp transplant, Newshour - BBC World Service

Surgeon describes first skull and scalp transplant, Newshour - BBC World Service | Organ Donation & Transplant Matters Resources | Scoop.it

Surgeon Michael Klebuc describes the operation that was required to replace Jim Boysen's skull and scalp.

 

Dr Klebuc also describes the challenges with sourcing the appropriate size matched and colour matched composite tissue graft that was used to partially replace this patients own skull and scalp. The audio can be accessed via clicking on the banner headline.

 

A more detailed online report of the planning that was required as well as the conduct of the surgery and the aftercare of this patient can be accessed via the following link-

http://www.washingtonpost.com/news/morning-mix/wp/2015/06/05/texas-man-gets-worlds-first-skull-and-scalp-transplant-plus-a-new-kidney-and-pancreas/

 

Deborah Verran's insight:

This patient underwent both a composite tissue transplant as well as a combined kidney-pancreas solid organ transplant. This required the co-operation of multiple surgical teams as well as rigorous attention to both planning and undertaking the surgical procedure.

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Transplant Network Reaches Milestone of 500,000 Deceased Donor Organ Transplants

Transplant Network Reaches Milestone of 500,000 Deceased Donor Organ Transplants | Organ Donation & Transplant Matters Resources | Scoop.it

As of May 19, 2015, the national transplant allocation system developed by United Network for Organ Sharing has coordinated 500,000 organ transplants from deceased donors in the United States since its beginning in October 1987.

Deborah Verran's insight:

A significant mile stone was reached this last week by the United Network of Organ Sharing in the United States

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Drugs produce high hepatitis C eradication rates, even in patients with liver disease

Drugs produce high hepatitis C eradication rates, even in patients with liver disease | Organ Donation & Transplant Matters Resources | Scoop.it

This is the latest report of success being achieved with new direct anti-viral drugs in the treatment of hepatitis C.

 

Two clinical trials of antiviral drug combinations report that 12-week courses are leading to effective viral eradication for a high percentage of patients with chronic hepatitis C infection.

 

To read more on the particular drugs involved and what the exact results were please click on the banner headline.

Deborah Verran's insight:

Further evidence of the efficacy of some of the new antiviral agents for treating chronic hepatitis C. It is hoped that eventually there will be less patients requiring liver transplantation for liver disease due to this particular virus.

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Regenerative Medicine - JAMA: The Journal of the American Medical Association

Regenerative Medicine - JAMA:  The Journal of the American Medical Association | Organ Donation & Transplant Matters Resources | Scoop.it

This Viewpoint describes how regenerative medicine through advances in cell biology, biomaterial science, and biological molecule discovery can replace or regenerate human cells, tissues, and organs harmed by disease or injury. However the full replacement of solid organs remains at this stage a vision, with many barriers needing to be overcome via ongoing laboratory research.

 

The first page of the article can be viewed by clicking on the banner headline. The full article requires access to a subscription to JAMA or can be purchsed online

Deborah Verran's insight:

This is one of a steady stream of review articles appearing regularly in the scientific literature on this relatively new area in medicine.

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Europe's first heart transplant from a donation after circulatory death organ donor

Europe's first heart transplant from a donation after circulatory death organ donor | Organ Donation & Transplant Matters Resources | Scoop.it

Surgeons at the Papworth hospital in Cambridgeshire, the United Kingdom have performed the first successful heart transplant in Europe using a heart retrieved from a donation after circulatory death (DCD) organ donor.

 

 Importantly the heart was placed on the TransMedics organ Care System device (pictured), following its removal from the deceased donor. This allowed for an assessment to be made as to the suitability of the heart to then be transplanted. A video which includes footage of the man who received the donor heart can be accessed by clicking on the banner headline.

 

This follows on from the report from Australia of two successful heart transplants from DCD organ donors in 2014 http://sco.lt/7Z57IX

 

Deborah Verran's insight:

News that a second heart transplant programme has successfully transplanted the heart from a DCD organ donor

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The BiVACOR artificial heart: developed in Queensland Australia

The BiVACOR artificial heart: developed in Queensland Australia | Organ Donation & Transplant Matters Resources | Scoop.it

This story is about a new type of artificial heart which has been developed in Australia and is now being trialed in a large animal model. This type of heart is unusual in that the flow of blood is not intermittent, hence there is no pulse which can be detected in the recipient.

 

The full article contains information about the developers, the collaborative partnerships that have been required to ensure the research could get to this stage as well as more information about the device itself. This can be accessed by clicking on the banner headline.

 

The hope is that this type of device will ultimately be trialed in humans. If it is successful then it could be an alternative to conventional heart transplantation in selected cases.

Deborah Verran's insight:

Well put together article, containing fine graphics. A must read for anyone interested in medical technology

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Overcoming the barriers to organ transplants in Bolivia

Overcoming the barriers to organ transplants in Bolivia | Organ Donation & Transplant Matters Resources | Scoop.it

This report comes via the Associated Press in LA PAZ, Bolivia (AP).

and features the case of a woman who finally received a live donor kidney transplant towards the end of 2014 as part of a new government sponsored initiative. This involves promoting organ transplantation as well as working on overcoming pre-existing cultural barriers, some of which are explored in the article.

 

Prior to the transplant Maria Ramos battled bouts of depression for seven years as she underwent thrice-weekly dialysis treatments to keep her alive.  Her ambition of becoming a schoolteacher at times was previously an unattainable dream.

 

 

Deborah Verran's insight:

News from Bolivia of some of the measures being taken to improve the rates of organ transplantation

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Pregnancy Outcomes are Similar for Adult and Child Female Kidney Transplant Recipients

Pregnancy Outcomes are Similar for Adult and Child Female Kidney Transplant Recipients | Organ Donation & Transplant Matters Resources | Scoop.it

Pregnancy outcomes are similar for women who have received a kidney transplant, whether they were a child or an adult at the time when they got their transplant, according to a new study published in the February issue of JAMA Pediatrics.

 

These are the conclusions of researchers who analysed data held in the ANZDATA Registry.

Deborah Verran's insight:

Important data which can be used to help guide clinicians in offering advice to women of child bearing age post kidney transplantation

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Pitt-UPMC exploring way to keep donated livers viable longer via machine preservation

Pitt-UPMC exploring way to keep donated livers viable longer via machine preservation | Organ Donation & Transplant Matters Resources | Scoop.it

Livers and other organs begin lacking oxygen the moment they are removed from the organ donor and hence may have sustained damage by the time a transplant occurs.

 

In cases where the circulation to the liver has ceased for a period of time prior to its removal from the organ donor, the damage to the liver can be greater.

 

This report outlines the use of a liver preservation machine that was initially developed in Europe as part of ongoing research efforts into the optimal method of preserving donor livers. To read more on this story click on the banner headline.

Deborah Verran's insight:

The preservation machine featured in this article is one of two that have initially been developed in Europe. It is now being used in preliminary trials by some liver transplant programmes around the world. Data on liver transplant outcomes utilizing this technology are expected to be available in another 1-2 years. 

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Investigation being undertaken of the organ donor retrieval process for a case in Germany

Investigation being undertaken of the organ donor retrieval process for a case in Germany | Organ Donation & Transplant Matters Resources | Scoop.it

The German Medical Association is investigating an incident where surgeons began to operate on a north German man who was not strictly brain dead.

 

The specifics of the case are not known however it has been confirmed that an investigation will now be undertaken for a case where concerns have been expressed around the sequence of events during organ retrieval surgery.

Deborah Verran's insight:

It is essential that the certification of brain death follows established protocols and standards to prevent unintended consequences.

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Simple steps can safeguard against Ebola transmission through organ donation in the United States

Simple steps can safeguard against Ebola transmission through organ donation in the United States | Organ Donation & Transplant Matters Resources | Scoop.it

While serious infections can be transmitted from donated organs, the risk of passing Ebola virus disease from an organ donor to a recipient is extremely small.

 

This is the conclusion reached by researchers in the United States in a recent editorial published in the American Journal of Transplantation.

 

As there is no readily available blood test available in all regions which could provide a rapid answer to whether or not a potential organ donor was harboring Ebola a safer strategy is to rely on the donors' recent history.

Deborah Verran's insight:

Steps are being taken within the United States to put safeguards in place across the organ donation system to prevent Ebola transmission occurring.

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From unknown to mainstream, Gift of Life program in Philadelphia turns 40

From unknown to mainstream, Gift of Life program in Philadelphia turns 40 | Organ Donation & Transplant Matters Resources | Scoop.it

The Gift of Life Organ Procurement Organization (OPO) has been responsible for the delivery of key services related to organ and tissue donation to the local region for 40 years.

 

The long-time CEO Howard Nathan reflects on nearly four decades in the organ donation and procurement business.

 

Howard provides insights into what it took to take a fledgling organization on a journey towards turning it into one of the leading OPO's within the United States.

Deborah Verran's insight:

A must read for healthcare professionals interested in leadership and management of organizations responsible for key aspects of services delivery within the healthcare sector pertaining to organ and tissue donation.

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In death, doctor's organ donation mission receives new life

In death, doctor's organ donation mission receives new life | Organ Donation & Transplant Matters Resources | Scoop.it

The recent death of a middle aged Canadian anesthesiologist (anaesthetist) who then went on to be an organ donor has attracted media attention.

 

During her life Dr Jennifer Bender had publicly advocated for organ donation. Hence it came as a shock to everyone who knew her when she recently collapsed and went on to die in hospital.

 

Mourning colleagues have been quick to point to the eight or so lives that may have been saved by Jennifer Bender’s thoughtfulness and discussions with her immediate family about organ donation.

 

The rest of this story can be vewed by clicking on the banner headline.

Deborah Verran's insight:

A reminder of the importance of both thinking about organ donation and having the chat with family members even if you are relatively young and seem to be in good health.

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Intensive care practices in brain death diagnosis and organ donation - Escudero - 2015 - Anaesthesia - Wiley Online Library

Intensive care practices in brain death diagnosis and organ donation - Escudero - 2015 - Anaesthesia - Wiley Online Library | Organ Donation & Transplant Matters Resources | Scoop.it

This abstract is from an early view article about Intensive care practices around the declaration of Brain Death for the purposes of organ donation in Spain. The link to the abstract is via http://t.co/7RD8ncfiLl

 

Access to the full article is via a paid subscription.

Deborah Verran's insight:

This article will be of interest to healthcare professionals involved in the identification and management of potential organ donors particularly in the intensive care unit

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Kidneys for sale: Iran’s trade in organs

Kidneys for sale: Iran’s trade in organs | Organ Donation & Transplant Matters Resources | Scoop.it

Iran is the only country in the world where it is legal to sell a kidney. Donors get money from the buyer and from the state, a system which eradicated waiting lists but, detractors say, now exploits the poor and vulnerable. Here, we follow one terrible story.

 

To read the full story click on the banner headline. There is also a photo library of images available for viewing which relate to the story.

Deborah Verran's insight:

This article exposes the harsh reality of a poor family selling virtually everything they have in order to 'buy' a live donor kidney for their son. This story does not have a happy ending.

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An unexpected microbe is lethal for some organ transplant recipents - Science /AAAS

An unexpected microbe is lethal for some organ transplant recipents - Science /AAAS | Organ Donation & Transplant Matters Resources | Scoop.it

A just released research study points the finger at a certain type of bacteria that can cause a lethal increase in the ammonia levels of lung transplant recipients which can then lead on to death.

 

For the first time as the result of scientific detective work the organisms concerned (Ureaplasma type bacteria), appear to become problematic for lung transplant recipients if they become infected with them.

Deborah Verran's insight:

A significant break through in determining a cause for some of the unexplained deaths in lung transplant recipients

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Inside the hospitals performing thousands black market organ transplant procedures

Inside the hospitals performing thousands black market organ transplant procedures | Organ Donation & Transplant Matters Resources | Scoop.it

In India, where these pictures were taken, around 2,000 people are thought to illegally sell their kidneys each year on the black market. This article exposes this practice and provides some estimates on how many of these type of procedures may be being performed per year internationally.

 

The language used to describe the conditions in some of the hospitals where these particular surgeries are being undertaken is not mild. For further information click on the banner headline.

Deborah Verran's insight:

More evidence of what happens when desperate patients link up with desperate individuals who are prepared to sell their own organs with brokers acting as the so called 'middle men'.

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Surgeons announce world's first successful penis transplant - Washington Post

Surgeons announce world's first successful penis transplant - Washington Post | Organ Donation & Transplant Matters Resources | Scoop.it

The announcement has been made of the worlds first successful penis (penile transplant). This is only the second time a penile transplant has been attempted, and this is the first time that  it has worked.

 

It took a surgical team nine hours to accomplish the surgery and there were constraints around sourcing the penis from a deceased donor.

 

The announcement was followed by a reporter who tweeted out information in a series of tweets which form the basis of this particular online report.

 

Another media report can be accessed via the following link-

http://www.medicaldaily.com/worlds-first-successful-penis-transplant-man-receives-new-sex-organ-after-9-hour-325604

 

Deborah Verran's insight:

This particular type of rare composite tissue transplant requires that a number of conditions be met. This includes the need to balance the long term risks of immune suppressing drugs versus the need to provide a young man with a fully functional penis. 

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Bionic reconstruction gives men first prosthetic hands controlled by mind

Bionic reconstruction gives men first prosthetic hands controlled by mind | Organ Donation & Transplant Matters Resources | Scoop.it

Three Austrians have had their injured limbs amputated, then nerves and muscles have been transplanted from the leg to the arm in each case so that the patients could learn to control their new prosthetic hands.

 

This is the online report summarizing the results of research that has just been published online in the medical journal The Lancet. This new approach to replacing damaged limbs with a hybrid of the patients own tissues and robotic type technology appears to be extremely promising.

 

A video of the functional results with use of the new bionic arm in practice can be viewed via the link which can be accessed by clicking on the banner headline or via the following link-

http://www.theguardian.com/science/video/2015/feb/25/world-first-bionic-hand-controlled-by-mind-video

 

 

Deborah Verran's insight:

Extraordinary development. This approach avoids the risks associated with life long anti-rejection therapy which is required for patients who may instead undergo arm transplantation.

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Why is organ & tissue donation taboo for Kenyans?

Why is organ & tissue donation taboo for Kenyans? | Organ Donation & Transplant Matters Resources | Scoop.it

It appears that deeply engrained religious and cultural beliefs prevent people in Kenya from donating both organs and tissues but some doctors are trying to change attitudes, writes Anne Soy.

 

There is an urgent need for corneas that can then be used to correct the vision of patients affected by disorders of the cornea including keratoconus. Although corneas are imported into Kenya, the cost is prohibitive for many patients as well as the health system. Hence there is a real need to improve the rates of tissue donation along with the rates of organ donation in Kenya so that more patients can benefit.

 

Attempts are being made to educate people in the community with some of the medical professionals now raising awareness of the importance of organ and tissue donation in order to assist with leading the efforts to achieve much needed change in Kenya.

Deborah Verran's insight:

Well written article outlining some of the barriers to organ and tissue donation in Kenya

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India's #1 Impediment To Organ Donation: Doctors - Huffington Post India

India's #1 Impediment To Organ Donation: Doctors - Huffington Post India | Organ Donation & Transplant Matters Resources | Scoop.it

This opinion piece comes via Dr Christopher Barry a Transplant Surgeon who has been spending time in India. Dr Barry shares his perspectives on where he feels the current barriers currently exist to improving the rates of deceased donor organ transplantation across India.

 

The article focuses on barriers within the healthcare system including in particular where medical specialists may be contributing to a lack of forward progress. All doctors and medical professionals across India also need to understand that organ donation is all about saving lives, despite a single loss of life.

Deborah Verran's insight:

A unique perspective on barriers that exist within the healthcare system across India to organ donation.

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Desperately needed organs from anonymous living donors are saving lives but raise ethical concerns

Desperately needed organs from anonymous living donors are saving lives but raise ethical concerns | Organ Donation & Transplant Matters Resources | Scoop.it

The National Post in Canada was recently invited to document one woman's altruistic living kidney donation — an act that still generates controversy and is even banned in some U.S. hospitals. In the process an exploration was undertaken to also explore some of the ethical issues around altruistic live organ donation which contribute to the reluctance of some transplant hospitals to offer this service.

 

Concerns over the safety and the long term well being of a live organ donor who is not related in any way to the transplant recipient have helped contribute to the high degree of caution around this process.

 

The live donor featured in this article is interviewed along with members of her surgical team as well as other health professionals with expertise in the assessment of live organ donors. The full text of this interesting article can be viewed by clicking on the banner headline.

Deborah Verran's insight:

A well written article that will be of interest to anyone with an interest in live organ donation

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Older donors could help reduce organ transplant gap: Canadian Report

Older donors could help reduce organ transplant gap: Canadian Report | Organ Donation & Transplant Matters Resources | Scoop.it

Canada could reduce its persistent shortage of organs for transplant by retrieving more organs from older donors, says a study released Thursday by the Canadian Institute for Health Information. 

 

The variability seen in the rates of organ donation as well as the variation in the demographics of organ donors across the country has led to a closer examination of where the potential exists to increase the rates of organ donation.

 

The report highlights what can be viewed as the current missed opportunities to increase the rates of organ donation across Canada.

 

The link to the full report -

 

http://www.cihi.ca/cihi-ext-portal/internet/en/document/types+of+care/specialized+services/organ+replacements/release_18dec14

 

Deborah Verran's insight:

Variation between the provinces in Canada has led to this closer examination of data pertaining to organ donation. The recommendations are sound and the whole report is worth reading. This will be of interest to professionals who hold the responsibility and/or interest in the performance of health care systems pertaining to organ donation.

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Top marks for organ donation in Scotland

Top marks for organ donation in Scotland | Organ Donation & Transplant Matters Resources | Scoop.it

The latest Report card from Scotland reveals that there has been significant increase in the rates of organ donation and transplantation in recent years.

 

The full media release can be accessed via the following link-

http://news.scotland.gov.uk/News/Top-marks-for-organ-donation-in-Scotland-1255.aspx

 

 

 

Deborah Verran's insight:

Good news from Scotland

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