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Study reports liver donors face mortality risk with LDLT - from News-Medical.Net - News-Medical.net

Study reports liver donors face mortality risk with LDLT - from News-Medical.Net - News-Medical.net | Organ Donation & Transplant Matters Resources | Scoop.it

Published Study reports that live liver donors face a mortality risk with LDLT  A study published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplant Society has revealed what are the current estimated risks for morbidity and mortality with adult live liver donation...

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Organ Donation & Transplant Matters Resources
Combining reports, research findings and topic reviews
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How organ donation is getting nudge in the right direction in the United Kingdom - The Independent

How organ donation is getting nudge in the right direction in the United Kingdom - The Independent | Organ Donation & Transplant Matters Resources | Scoop.it

This report via The Independent outlines how organ donation is getting a nudge in the right direction within the United Kingdom.

For years the NHS has grappled with the conundrum of how to increase the number of people on Britain's Organ Donor Register. Now the results of some interesting research has revealed what type of messaging is most likely to resonate with members of the community.

 

Postive messages which are appealling to individuals are more likely to work versus messages outlining the harsh realities of potential transplant recipients.

 

Examples of the questions that were asked for this research are outlined in the following article-

http://www.dailymail.co.uk/news/article-2528726/Selfish-ploy-attract-100-000-new-organ-donors-year.html

 

An update of the results of this research were published online in March 2014-

http://tom.loosemore.com/2014/03/18/one-link-on-gov-uk-350000-more-organ-donors/

 

Deborah Verran's insight:

Effective messaging that is directed  to members of the community about organ donation, seems far more likely to lead to public engagement and hence the appropriate actions being taken

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Don't Take 'No' for an Answer: An Experiment with Actual Organ Donor Registrations in the USA

Don't Take 'No' for an Answer: An Experiment with Actual Organ Donor Registrations in the USA | Organ Donation & Transplant Matters Resources | Scoop.it

Results of this research by Judd E. Kessler and Alvin B Roth outline the impact of active choice on decision making with respect to organ donation. Some of the findings may come as a surprise.

 

It appears that there are a number of findings that emanate from this research-

 

a) it is useful to encourage people to join organ donor registries

b) it is important to keep asking the question about organ donation

c) however active choice can also lead to a downside which is manifest by the rate of 'family refusals' at the time that the potential scenario then becomes a reality

Deborah Verran's insight:

Thoughtful analysis of an important issue posted online via Harvard Business. Professor Alvin Roth is a Nobel Prize laureate.

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How Much for a Kidney? Should live donors be compensated?

How Much for a Kidney? Should live donors be compensated? | Organ Donation & Transplant Matters Resources | Scoop.it

How best to encourage and support organ donation is the subject of an this online series of articles which debate this topic.


Titled How Much for a Kidney? the series is published via the New Yprk Times and focuses on kidney transplantation. 

 

According to the World Health Organization, 80,000 kidney transplants are performed worldwide each year, yet the demand now out strips the supply of donor kidneys.

 

To access the series of articles, click on the banner headline.

 

To read the article on why the testing of well thought out incentives for organ donation now needs to be considered click on the following link-

http://www.nytimes.com/roomfordebate/2014/08/21/how-much-for-a-kidney/test-incentives-for-organ-donations-theres-no-reason-not-to

 

Deborah Verran's insight:

Polished, professional series of viewpoints on how best to increase organ donation published via the New York Times

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US FDA approves XVIVO lung preservation device

US FDA approves XVIVO lung preservation device | Organ Donation & Transplant Matters Resources | Scoop.it

The U.S. Food and Drug Administration has approved the XVIVO Perfusion System (XPS) with STEEN Solution, a device for preserving donated lungs that do not initially meet the standard criteria for transplantation.

 

The XVIVO XPS lung perfusion system is one of several devices currently being trialed around the world. It is now hoped that with the judicious use of this type of technology that more donor lungs will be deemed suitable for transplantation. Once this technology becomes more widely available it is anticipated that this should lead to an increase in the numbers of lung transplants over the next 2-5 years.

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'Heart in a box': Pioneering device keeps donor organs alive OUTSIDE the body

'Heart in a box': Pioneering device keeps donor organs alive OUTSIDE the body | Organ Donation & Transplant Matters Resources | Scoop.it


Traditionally, all donor organs are placed in a cool-box and surrounded by ice to prevent them deteriorating on their journey between hospitals.

 

However new technology in the form of transportable machines is

leading to changes in how some organs are maintained following their removal from the donor.

 

This report focuses on the preliminary experience with the use of normothermic machine preservation in the Harefield heart transplant programme in the United Kingdom

Deborah Verran's insight:

Another report on the preliminary use of machine preservation in heart transplantation. Further data from the prospective clinical trials that are currently being undertaken is now awaited

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Chief Medical Officer appointed to a US OPO

Chief Medical Officer appointed to a US OPO | Organ Donation & Transplant Matters Resources | Scoop.it

This last week one of the US Organ Procurement Organization's announced that it had appointed a physician to a top medical post

Following a successful initiative to improve the viability of donated organs, Mid-America Transplant Services (MTS) named Dr Marklin as its new CMO.

Deborah Verran's insight:

Part of an evolving trend to have physicians involved in OPO operations in light of the specialized nature of many of the aspects of organ donor assessment and management

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The Importance of Managing Mission Knowledge at NASA

The Importance of Managing Mission Knowledge at NASA | Organ Donation & Transplant Matters Resources | Scoop.it

Reported online via T + D is this article titled Managing Mission Knowledge at NASA
 
This fundamental question lies at the heart of NASA's efforts in knowledge management (KM), and as explained in the article due to the nature of the work undertaken by NASA, failure can be costly.

Deborah Verran's insight:

This article will be of interest to professionals who are tasked with dealing with knowledge management within organizations

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Nepal's Organ Trail: How traffickers steal kidneys

Nepal's Organ Trail: How traffickers steal kidneys | Organ Donation & Transplant Matters Resources | Scoop.it

Reported online via the CNN Freedom Project. In Nepal, organ traffickers are duping villagers into having operations and taking their kidneys.

 

Click on the banner headline to read more about this story

Deborah Verran's insight:

Yet another example of 'needy' individuals being paid (not a lot of money) to donate one of their kidneys with brokers involved in the transactions. Of most concern is how some of the donors are being coerced into actually going ahead.

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New Stanford blood test identifies heart-transplant rejection earlier than conventional biopsy - Stanford Medical Center Report

New Stanford blood test identifies heart-transplant rejection earlier than conventional biopsy - Stanford Medical Center Report | Organ Donation & Transplant Matters Resources | Scoop.it

Reported online via the Stanford Medical Center Report the news that
a blood test can identify heart-transplant rejection at an earlier stage than a conventional biopsy (as pictured).

 

The test detects of circulating donor DNA in the blood of heart transplant recipients. As this is a preliminary report more experience needs to be gained with this test prior to it becoming a possible addition to the current laboratory testing that is used to help monitor transplant recipients.

Deborah Verran's insight:

The next phase in the investigation of 'biomarkers' that will assist in the management of heart transplant recipients

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Life, Death and the Organ Allocation System - Lawfuel

Life, Death and the Organ Allocation System - Lawfuel | Organ Donation & Transplant Matters Resources | Scoop.it

This opinion piece posted online under the title "Life, Death and the Organ Allocation System" is written by a lawyer in the United States.

 

On the one-year anniversary of the Sarah Murnaghan lung allocation case, Philadelphia litigator Steve Harvey writes about about the case as well as the factors behind the ongoing critical shortage of organs within the United States.

Deborah Verran's insight:

Thoughtful, well written and of interest to professionals involved in organ donation

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Barriers To Knowledge Sharing

Barriers To Knowledge Sharing | Organ Donation & Transplant Matters Resources | Scoop.it

Knowledge sharing is the corner-stone of many organisations’ knowledge-management (KM) strategy. Despite the growing significance of knowledge sharing’s practices for organisations’ competitiveness and market performance, several barriers make it difficult for KM to achieve the goals and deliver a positive return on investment.

 


Via Kenneth Mikkelsen
Deborah Verran's insight:

The barriers to KS can occur at the level of the individuals, within organizations or between organizations. This article elegantly outlines how and why these barriers may exist.

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Ignasi Alcalde's curator insight, May 26, 4:16 AM

Knowledge Management basics and barriers

 

 

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What Makes a Good Chairman?

What Makes a Good Chairman? | Organ Donation & Transplant Matters Resources | Scoop.it

What are the qualities of strong board chairs? This online posting provides an outline on what are currently perceived to be the important qualities (& skill sets) of board chairs. This incldues leadership and doing the 'right thing'.

 

http://t.co/1355cnIJvI


Deborah Verran's insight:

This article will be of interest to healthcare professionals who hold leadership roles and have governance responsibilities

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Transplant patient wins payout over kidney from donor with cancer

Transplant patient wins payout over kidney from donor with cancer | Organ Donation & Transplant Matters Resources | Scoop.it

Reported via The Guardian in the United Kingdom that Robert Law (pictured) aged, 62, had to undergo six cycles of chemotherapy after receiving a kidney from woman who had lymphoma http://t.co/EKEVGfRdug)...

 

More background information on the case can be found by clicking on the link

Deborah Verran's insight:

Comprehensive processes are required in organ donation systems to prevent the overlooking of critical information which can then lead to adverse consequences

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Organ donation: is an opt-in or opt-out system better?

Organ donation: is an opt-in or opt-out system better? | Organ Donation & Transplant Matters Resources | Scoop.it


Around the world, organ donation policies vary greatly between countries. So is it better to have a donation system where people have to opt in or one where they opt out?

 

This question was asked recently by some researchers in the United Kingdom. They examined the rates of organ donation in a number of countries around the world according to whether opt in or opt out types of legislation were in place.

 

There appears to be higher rates of deceased donor organ donation in countries with an opt out system whilst the opposite was true for living donation. As outlined in this article there are other factors which contribute to the rates of organ donation both within and between countries.

 

The ex CEO of BC Transplant in Canada (Bill Barrable) outlines why moving to a presumed consent system was not supported back in time within Canada -

 

http://www.theglobeandmail.com/globe-debate/organ-donation-the-perils-of-presumed-consent/article20783431/?__scoop_post=2cd7f780-450d-11e4-a362-001018304b75&__scoop_topic=543333#__scoop_post=2cd7f780-450d-11e4-a362-001018304b75&__scoop_topic=543333

 

Finally, the results of some recently published research on whether there is a region of the brain which can be identified to be associated with altruism in live kidney donors can be viewed via this link-

 

http://www.medicaldaily.com/organ-donor-brains-bigger-region-linked-altruism-neural-roots-generosity-303638?__scoop_post=e685b850-4244-11e4-f327-001018304b75&__scoop_topic=543333#.VB_emdJ6-m4.twitter

 

 

 

 

Deborah Verran's insight:

The rates of organ donation within and between countries represent the end result of many factors which all need to be in place in order for optimal rates of organ donation to be sustained.

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Legal battle over organ donors' final wishes in the NW of the United States

Legal battle over organ donors' final wishes in the NW of the United States | Organ Donation & Transplant Matters Resources | Scoop.it

Recently in the United States a hospital sought resolution of a dispute between the known wishes of a potential organ donor and his family members.

 

As outlined in the article, the young man was declared brain dead as the result of fatal head injuries that he sustained in an automobile accident. It appears that during life, the man had declared his intent to be an organ donor when registering for his drivers license.

 

When family members were approached for authorization for the organ donation process to proceed they refused. At that point the hospital concerned took the matter to court.

 

The organ donation surgery then proceeded, two days following the court hearing. 

 

In this case the court has upheld the principle of 'first person authorization' which has been the subject of a previous post on this site-

 

http://sco.lt/6IC1dh

 

Deborah Verran's insight:

Their are some inaccuracies in the online report. First organ retrieval surgery is not performed prior to death. Second the term 'harvest' is no longer deemed an appropriate descriptor of the surgical organ recovery process.

 

The case does bring home the importance of family members all being aware of their loved ones wishes when it comes to organ donation.

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Kidneys for Sale - Israel & Organ Trafficking

Kidneys for Sale - Israel & Organ Trafficking | Organ Donation & Transplant Matters Resources | Scoop.it

When investigators from the New York Times looked into an illegal organ trading operation based in Costa Rica, what they discovered was that all paths led to Israel.


The culprits (brokers),  were among the central operators in Israel's

irrepressible underground kidney market. 

 

Details on who the culprits were, along with what some of the patients also went through can be viewed by clicking on the banner headline.

 

One of the factors which contributes to patients becoming desperate is the low rates of organ donation in Israel. This is subject to a second article outlining in detail the barriers to organ donation in Israel-

 

http://sco.lt/54wOyP

 

In addition an interview with Kevin Sack of the New York Times can be viewed via the following link-

 

https://www.youtube.com/watch?v=f8fhMe6cuHU

 

Deborah Verran's insight:

Detailed story on the kidney transplant racket involving Israeli patients travelling to Costa Rica

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India has addressed blood donation, it must now do the same with organ donation

India has addressed blood donation, it must now do the same with  organ donation | Organ Donation & Transplant Matters Resources | Scoop.it

This detailed article outlines the multiple factors which contribute to an unmet need for organ donation within India.

 

Although living kidney and living liver transplantation are both performed, these are costly procedures and hence only available to those who can afford to pay.

 

A similar perspective from Dr Avnish Seth, the Director of Fortis Organ Retrieval & Transplant can be viewed via the following link-

http://blog.organdonationday.in/?p=30

 

 

Deborah Verran's insight:

There remain challenges within India with respect to establishing a robust system for deceased donor organ donation across the country

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Big Data's Effect on Organ Transplant Wait Lists in the United States

Big Data's Effect on Organ Transplant Wait Lists in the United States | Organ Donation & Transplant Matters Resources | Scoop.it

This report is about the challenges that have been faced in recent years in the United States with increasing numbers of people on transplant waiting lists and how the concept of paired kidney exchange arose. Hint it involved a Professor of Economics (Dr Alvin Roth) who was ultimately awarded the Nobel prize.

 

However there are still challenges with finding matches with paired kidney exchange schemes and the reasons are also outlined in this report.

Deborah Verran's insight:

Interesting report containing both statistics and background information

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Heart Transplant Footage Shows How Far Medical Science Has Come

Heart Transplant Footage Shows How Far Medical Science Has Come | Organ Donation & Transplant Matters Resources | Scoop.it

This report is about how heart transplantation has progressed over the last 45 years and contains video footage of a Heart Transplant procedure. 

Since the first transplant at one programme in the United States,

Stanford University Hospital in 1968, doctors and scientists have refined the operation to an astounding degree. The video can also be viewed by clicking on the following link-

https://www.youtube.com/watch?v=QGtLYtOwtxA

 

Deborah Verran's insight:

An example of quality video footage of a transplant procedure which has been posted online. Not for the squeamish however.

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NIH-funded researchers extend liver preservation for transplantation - EurekAlert (press release)

NIH-funded researchers extend liver preservation for transplantation - EurekAlert (press release) | Organ Donation & Transplant Matters Resources | Scoop.it

Reported online via EurekAlert is the news that NIH-funded researchers in the United States may have developed a new method for extending liver preservation for transplantation.

 

Transplants of skin, kidneys, hearts, lungs, corneas, and livers have become commonplace but due to a shortage of donor organs not all potential transplant recipients will receive a transplant in time.

 

Rat livers where able to be preserved for an extended period of time using a new super cooling method which is described in more detail in the report(click on banner headline).

 

For a more detailed report click on the following link to the NIH press release-

 

http://www.nih.gov/news/health/jun2014/nibib-30.htm

 

Deborah Verran's insight:

More research is now required to see whether this new process can be adapted for the cold preservation of human livers to allow for extended periods of storage prior to transplantation

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Transplant 'fairness' at issue for panel, Georgians

Transplant 'fairness' at issue for panel, Georgians | Organ Donation & Transplant Matters Resources | Scoop.it

A committee on liver transplants in the United States has indicated this last weeks that reducing the nation's number of transplant regions — from the current 11 to four (for the purposes of donor liver allocation) — could potentially save hundreds of lives.

 

However as outlined in detail in this article published online, the potential to save lives has to be balanced with utility of donor liver allocation as not all donor livers are of the same quality. This difference in the quality of donor livers currently places constraints on the time period in which they can be transplanted following removal from the donor.

 

The article focuses on the concerns held by surgeons at a transplant programme in Atlanta, Georgia as to how the new scheme would work. To read more on this story click on the banner headline.

Deborah Verran's insight:

In countries with large geographic regions the allocation of donor livers requires a balancing of equity with utility taking into account all of the factors which impact on donor liver utilization.

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Flock Associates - Recife Sport club: Immortal Fans. Integrated Marketing by Ogilvy Brazil - YouTube

A report via Brazil which will resonate with soccer fans around the world as the Soccer World cup begins. This story was initially  reported online via http://www.flock-associates.com

 

Taking advantage of the strong bond and enormous pride that Recife fans felt towards their soccer team, Ogilvy & Mather Brazil engineered a campaign to encourage the fans to sign up to be organ donors

 

The results have been amazing and are a testament to the power of passion for a sport translating into a benefit for the community as outlined in this short YouTube video

Deborah Verran's insight:

Soccer fans in Brazil are not only passionate about their sport but in the case of one club are passionate about organ donation as well

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Organ donation infographic & event - BAME communities

Organ donation infographic & event - BAME communities | Organ Donation & Transplant Matters Resources | Scoop.it

As a result of outreach activities held in the United Kingdom the data that have been obtained have been analysed and converted into an infographic.

 

This organ donation infographic summarises the key insights for theawareness and support for organ donation amongst Black, Asian and Minority Ethnic (BAME) communities.

 

For more information, click on the banner headline.

Deborah Verran's insight:

Interesting data from the United Kingdom on the levels of knowledge and awareness in the BAME communities

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Kidney transplant patients live longer than those in intensive home hemodialysis - Medical Xpress

Kidney transplant patients live longer than those in intensive home hemodialysis - Medical Xpress | Organ Donation & Transplant Matters Resources | Scoop.it

Analysis of data from a research study performed in Canada has revealed that Kidney transplant patients live longer than those receiving intensive home hemodialysis.

 

A first-ever study from a large Canadian centre has found that kidney

transplant recipients lived longer and had better treatment success regardless of what type of donor kidney that they received. 'Kidney transplant is still the best treatment option says Dr Chris Chan (pictured) who is a nephrologist at the Toronto General Hospital.

 

To read more about the findings of this study, click on the banner headline.

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How best to encourage organ donation: Research brief - Journalist's Resource

How best to encourage organ donation: Research brief - Journalist's Resource | Organ Donation & Transplant Matters Resources | Scoop.it

From the Journalist's Resource web site of the Harvard Kennedy School, Sorenstein Centre on Media, Politics and Public Policy comes this article titled: How best to encourage organ donation.

 

The Research brief Journalist's Resource Physicians have taken up this cause as well, along with recent editorials in the Clinical Journal of the American Society of Nephrology and Medscape. It is apparent that even if the potential of the deceased donor organ donation pool was fully realized within the United States, that there would still be a gap in the numbers of people  awaiting kidney transplantation and the number of available donor organs.

 

Hence the additional importance of live kidney donation and why this particular article contains the conclusion that other measures now need to be adopted within the United States.

Deborah Verran's insight:

Interesting article out of the United States

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An About-Face on a Risky Transplant - New York Times

An About-Face on a Risky Transplant - New York Times | Organ Donation & Transplant Matters Resources | Scoop.it

An About-Face on a Risky Transplant. This report outlines in detail how medical professionals have now come to accept that face transplantation has a place in the management of patients who have sustained severe disfiguring facial trauma. It is accompanied by a series of detailed graphics which can be accessed by clicking on the banner headline.

When patient Richard Lee Norris, 37, received a full face transplant in 2012, years after a gun accident destroyed his chin, lips, teeth and nose. Doctors gave him a new jaw, teeth, tongue, skin and muscles.

Deborah Verran's insight:

Progress is being made with the understanding of how face transplantation has a role in the management of selected patients

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