Organ Donation & ...
Follow
Find
5.8K views | +0 today
 
Scooped by Deborah Verran
onto Organ Donation & Transplant Matters Resources
Scoop.it!

Liver Transplantation — A Vision Realized — NEJM

Liver Transplantation — A Vision Realized — NEJM | Organ Donation & Transplant Matters Resources | Scoop.it

In this perspective published in the medical journal, The New England Journal of Medicine — Liver Transplantation — A Vision Realized, the history of how liver transplantation became a clinical reality is outlined.

 

The article focuses on pioneering surgeons Sir Roy Calne and Dr Thomas Starzl(joint winners of the Lasker award). The factors contributing to the success of liver transplantation included- development of surgical techniques, new immunosuppressant medications becoming available, the sourcing of livers for transplantation from deceased donors post declaration of brain death.

 

The UPMC media release and video of Dr Thomas Starzl reflecting on receiving the Lasker award can be viewed via the following link-

http://www.upmc.com/media/NewsReleases/2012/Pages/Starzl-Receives-2012-Lasker-Award.aspx

 

 A video on the history of these two surgeons achievements can be viewed via the Lasker Foundation link-

http://www.laskerfoundation.org/awards/2012_c_interview_calne.htm

 

 

more...
No comment yet.
Organ Donation & Transplant Matters Resources
Combining reports, research findings and topic reviews
Curated by Deborah Verran
Your new post is loading...
Your new post is loading...
Scooped by Deborah Verran
Scoop.it!

Tissue engineering: Organs from the lab - Nature.com

Tissue engineering: Organs from the lab - Nature.com | Organ Donation & Transplant Matters Resources | Scoop.it

The body's organs are more complex than any factory. Attempts to mirror their physiology in the laboratory are now getting closer to capturing their individual intricacies.

 

This well written article outlines the gains that have been made with organ and tissue engineering, particularly the "organ on a chip" technology which is now increasingly being used for research and testing purposes.

 

However due to the inherent complexities in all of the human organs there is still a lot more in the way of research which needs to be undertaken. This is in order to allow step wise progress in the bioengineering of organs to be made.

Deborah Verran's insight:

The latest summary of this fascinating area of ongoing research.

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Organ Transplants Up Slightly in the United States, Hospitals Urged to Do More

Organ Transplants Up Slightly in the United States, Hospitals Urged to Do More | Organ Donation & Transplant Matters Resources | Scoop.it

Recently it was reported that there had been an increase in the number of organ transplants performed within the United States for 2015 compared to 2014.

 

However this does not mean that efforts to improve on this outcome now cease. In this article published online, several of the leaders in the Organ Procurement Network outline their thoughts on what needs to happen in order to improve on this outcome. One.transplant surgeon is quoted as stating that  "registering donors is "part of our responsibility as caregivers".

Deborah Verran's insight:

A thought provoking article which will be of interest to healthcare professionals with leadership and/or management roles in both organ donation and transplantation.

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Draft guidelines issued to tackle illegal kidney trade - The Times of India

Draft guidelines issued to tackle illegal kidney trade - The Times of India | Organ Donation & Transplant Matters Resources | Scoop.it

In a move to bring in greater transparency and tackle the illegal kidney trade while prioritising those in urgent need of renal transplant across India, the National Organ and Transplant Centre has come out with draft guidelines that aim to determine the criteria for receiving a kidney from a deceased donor.

 

This is the first stage in a process that has commenced within India of moving to a national centrally co-ordinated system for the allocation of all organs from deceased donors.

Deborah Verran's insight:

This will be of interest to healthcare professional with an interest in policy guidelines pertaining to organ donation as well as organ transplantation,

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Kidney donor’s death a ‘nightmare scenario’ for UCSF program

Kidney donor’s death a ‘nightmare scenario’ for UCSF program | Organ Donation & Transplant Matters Resources | Scoop.it

News from the United States that the University of California San Francisco (UCSF) has suspended its live donor kidney transplant program whilst an investigation is carried out into the recent death of a live donor following surgery.  

 

UCSF’s suspension of its living donor program for kidney transplants this week after the death of a donor highlights a rare but potential complication for a procedure that’s typically an altruistic gift by a friend or family member to a patient who requires a kidney transplant.

 

For more on this story click on the banner headline....

Deborah Verran's insight:

A reminder that live kidney donation involves major surgery both for the donor as well as the recipient and hence is not risk free.

 

Results of the investigation into the death of this particular donor are now awaited

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

ViosWorks MRI Software Visualizes Blood Flow In and Around Heart (VIDEO)

ViosWorks MRI Software Visualizes Blood Flow In and Around Heart (VIDEO) | Organ Donation & Transplant Matters Resources | Scoop.it

At RSNA in Chicago this last week GE Healthcare introduced its ViosWorks software for analyzing cardiac MRI scans.

 

The software allows for the real time imaging of blood flow which is evident in the video which is contained within this online article. This can be accessed via clicking on the banner headline.

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Charges brought against makers of dietary supplement linked to liver damage - PBS NewsHour

Charges brought against makers of dietary supplement linked to liver damage - PBS NewsHour | Organ Donation & Transplant Matters Resources | Scoop.it

A Dallas company that had been ordered to recall a dietary supplement pill because of links to liver damage has now been indicted along with several of its executives on charges that they intentionally mis-branded their products and then continued to sell them.

 

 This is a postscript to the chain of events involving a nutritional supplement marketed under the label OxyElite Pro which was associated with cases of acute liver failure, particularly within the United States. Some of the patients with acute liver failure subsequently required liver transplantation due to the severity of their medical condition.

Deborah Verran's insight:

A cautionary tale of a chain of events surrounding a nutritional supplement that failed to meet regulatory standards within the United States.

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Campaign uses Apple Store opening queue clip to encourage organ donor registration

Campaign uses Apple Store opening queue clip to encourage organ donor registration | Organ Donation & Transplant Matters Resources | Scoop.it

A Belgian campaign group used the queue for the recent opening of the Apple Store in Brussels to create a clever video encouraging people to register as organ donors. People on the waiting list for organ transplantation switched places with people waiting for the latest Apple gadgets in exchange for a commitment to register as an organ donor.

 

The video can be accessed via the landing page which is accessed via clicking on the banner headline.

Deborah Verran's insight:

Clever analogy of waiting in line compared to waiting on an organ transplant waiting list

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Human leg is STOLEN from OneLegacy van en route to a tissue donation in California

Human leg is STOLEN from OneLegacy van en route to a tissue donation in California | Organ Donation & Transplant Matters Resources | Scoop.it

The theft of a human leg from a vehicle occurred early this last week as employees of nonprofit organization OneLegacy were eating at The Original Pantry Cafe in Los Angeles.

 

The theft is now being investigated by authorities as it is illegal to steal human body parts in Western Countries. For more on the story click on the banner headline.

Deborah Verran's insight:

A reminder that it is illegal to interfere with a human body or parts thereof following death.

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Organ transplants decline in number - The Slovak Spectator

Organ transplants decline in number - The Slovak Spectator | Organ Donation & Transplant Matters Resources | Scoop.it

This report outlines how Slovakia has fallen behind neighbouring countries when it comes to the per annum rates of organ donors.

 

Mention is made of what are felt to be some of the possible contributory factors despite the fact that Slovakia has opt out legislation in place. In addition steps are now being taken to come up with possible solutions which may be implemented to help increase the rates of organ donation.

Deborah Verran's insight:

Interesting commentary on the current status of organ donation in Slovakia

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

$11mn, 36-hour historic head transplant to be carried out in China in 2017

$11mn, 36-hour historic head transplant to be carried out in China in 2017 | Organ Donation & Transplant Matters Resources | Scoop.it

Italian doctor Sergio Canavero, along with his Chinese colleague Ren Xiaoping, appear set to conduct the world’s first head transplant on a 30-year-old Russian patient (pictured) suffering from a rare degenerative disease. The operation is planned for December 2017.

 

Details remain sketchy at this stage as to how the donor body will be sourced along with as to which hospital will be involved.

 

Related video footage can be viewed via the following link-

https://youtu.be/YsgJPteCwww

 

Deborah Verran's insight:

The world now waits to see whether this so called planned procedure will actually now take place

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

New Bio-Sensors May Save Lung Transplant Patients from Organ Failure

New Bio-Sensors May Save Lung Transplant Patients from Organ Failure | Organ Donation & Transplant Matters Resources | Scoop.it

In the future a new system of sub classifying donor lungs, based on molecular profiling, could make more donor lungs available for transplantation purposes. 

 

This report is of new research on using a molecular probe in order to detect whether donor lungs may be at risk of poor early function following transplantation .

 

This is the first step in the use of this very modern technology in order to provide this particular type of extra information which can be used to assist with making decisions on whether donor lungs are suitable for transplantation. In addition the information may also be used to subclassify the donor lungs into whether they are considered normal or high risk organs for initial poor graft function following transplantation. More on this story can be viewed by clicking on the banner headline

Deborah Verran's insight:

This new molecular probe type of technology will need to be subjected to further trials so that a clearer picture can be gained of both its accuracy and validity 

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Researchers achieving improved outcomes with Pig-to-Primate Organ Transplants - MIT Technology Review

Researchers achieving improved outcomes with Pig-to-Primate Organ Transplants - MIT Technology Review | Organ Donation & Transplant Matters Resources | Scoop.it

A biotech company’s genetically engineered pigs are now setting new records for outcomes as the result of xenotransplantation of some of the organs into primates.

 

It appears that years of laboratory research are now beginning to deliver promising results with the use of these particular animal organs for transplantation purposes. It may be possible that if the results continue to improve that trials in humans may be contemplated in the not too distant future.

Deborah Verran's insight:

Good summary of the current status of xenotransplantation. The full article can be accessed by clicking on the banner headline.

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Organ donation: Faces at the front line - National - NZ Herald News

Organ donation: Faces at the front line - National - NZ Herald News | Organ Donation & Transplant Matters Resources | Scoop.it

Dr Emma Merry an Intensive Care Unit (ICU) Physician can still remember how nervous she felt the first time she spoke to a grieving family about the possibility of donating their loved one's organs. 

 

As Dr Merry explains in her interview for this story, there are a number of challenges faced by ICU physicians who are faced with dealing with the relatives of a potential organ donor who is in the ICU.

 

The article also delves into what are some of the possible contributory factors behind the relatively low rates of organ donation within New Zealand compared to many other Western countries.

Deborah Verran's insight:

Sound account from an ICU physician of the challenges that they face when dealing with a prospective organ donor. 

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Sri Lanka Suspends Kidney Transplants for Foreigners After India Arrests

Sri Lanka Suspends Kidney Transplants for Foreigners After India Arrests | Organ Donation & Transplant Matters Resources | Scoop.it

The Sri Lankan government last week suspended all kidney transplants for foreigners, after Indian police said they were investigating alleged organ sales.

 

This has come about following reports of organ trading involving individuals who then traveled from India to Sri Lanka in order to undergo the transplant surgery.

Deborah Verran's insight:

Results of the investigation are now awaited. Of note this pertains to live donor kidney transplantation.

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Leonard Bailey MD First paed heart transplant in the USA

HealthFeed provides the most trusted health video content on YouTube with a network of professional experts.

Doctors and experts provide research and expertise in a short succinct format.

 

Here Dr Leonard Bailey talks about the first paediatric heart transplant in the United States and how the lessons learnt helped pave the way for the successful cases which followed.

 

 

Deborah Verran's insight:

An interesting perspective on how paediatric heart transplantation became a clinical reality in the United States.

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

DCD heart transplant in China: Heart stops beating, revives 7 hours later

This is an online report of a successful heart transplant surgical procedure in east China. A heart transplant in Fujian Province was successful even though the donor organ had stopped beating for a period of time in the donor prior to its retrieval.

 

Although there is limited information in this video, it does seem that the donor heart was retrieved from a DCD donor and then transported to the recipient hospital where it was then transplanted.

Deborah Verran's insight:

This is an indication that heart transplantation from DCD donors is now proceeding in China

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Lanie Ross - When Altruism Goes Awry: Live Kidney Donors in End Stage Renal Disease

This lecture titled 'When Altruism Goes Awry: Living Kidney Donors in End Stage Renal Disease' was delivered via Lanie Ross, MD, University of Chicago November 13, 2015 

 

It explores what is known about live kidney donors who have gone on to develop end stage renal failure within the United States. It also outlines the current limitations of registry data and how this may be improved.

Deborah Verran's insight:

This talk will be of interest to healthcare professionals with a role in the oversight and management of living kidney donation.

more...
No comment yet.
Rescooped by Deborah Verran from Leadership
Scoop.it!

The 7 forms of courage every leader should demonstrate

The 7 forms of courage every leader should demonstrate | Organ Donation & Transplant Matters Resources | Scoop.it

Through years of consulting to many organizations, I’ve been blessed to work with wonderful, accomplished leaders......

 

This insight has led to the this author crafting this online article which breaks down the types of courage which are required from leaders if they are to remain effective in leading either teams or organizations


Via Anne Leong
more...
Sandeep Gautam's curator insight, November 26, 2015 1:35 AM

do you have the courage to be a leader?

Scooped by Deborah Verran
Scoop.it!

Inequality in US organ transplants: Researchers detail how the wealthy leverage the opportunity of being allowed on to multiple lists

Inequality in US organ transplants: Researchers detail how the wealthy leverage the opportunity of being allowed on to multiple lists | Organ Donation & Transplant Matters Resources | Scoop.it

It appears that in the United States patients who are financially well off are able to leverage a loop hole in the organ donation system. That is they are able to be on multiple waiting lists for an organ transplant.

 

As revealed by research that was recently presented at a medical scientific meeting, patients who were on wait lists at multiple centers had higher transplant rates. The reasons for this are explored further in the online article which can be viewed by clicking on the banner headline.

Deborah Verran's insight:

A unique loophole in the United States organ donation system provides patients who are well with the opportunity to be listed on more than one transplant centre's waiting list.

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Translating Evidence Into Practice via Social Media: A Mixed-Methods Study

Translating Evidence Into Practice via Social Media: A Mixed-Methods Study | Organ Donation & Transplant Matters Resources | Scoop.it

Background: Approximately 80% of research evidence relevant to clinical practice never reaches the clinicians delivering patient care. There are a number of reasons as to why this is the case.

 

However it may be possible to improve on this statistic via leveraging social media. This particular mixed methods study involved participants in a number of countries around the world  and adds to the current knowledge on the effective use of social media for educational purposes. The research study involved the streaming of curated information to a group of healthcare professionals over a period of time with both pre-test and post-test surveys being undertaken. 

 

For more information on this research as well as what the results were click on the banner headline.

Deborah Verran's insight:

This article will be of interest to healthcare professionals who have roles in knowledge management and knowledge sharing.

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Need a kidney? Inside the world’s biggest organ market

Need a kidney? Inside the world’s biggest organ market | Organ Donation & Transplant Matters Resources | Scoop.it

This report explores the illicit kidney trade in South Asia which has now exploded as brokers use social media to find donors.

 

In this detailed article it becomes evident to the reader that the information has been obtained by interviewing anonymous individuals who are currently involved in the trading of kidneys. It is very clear how the organ trading is now being facilitated and where it may currently be occurring.

 

Brokers are using social media platforms to assist in sourcing the potential live donors for recipients who are prepared to pay in order to receive a kidney.

 

This activity appears to involve individuals (and professionals) who are currently based both in India and Sri Lanka.

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Increasing Transplant Organ Supply Through Uncontrolled Donation After Circulatory Death

Increasing Transplant Organ Supply Through Uncontrolled Donation After Circulatory Death | Organ Donation & Transplant Matters Resources | Scoop.it

The whole issue of increasing transplant organ supply via the implementation of uncontrolled Donation After Circulatory Death pathways raises legal, ethical and moral issues.

 

This creates a number of challenges at the intersection of health, health care, and policy which are context specific, i.e. are dependent on the specific legislation as well as standards for practice which already exist within a number of countries around the world.

 

This particular article is written for a professional audience within the United States and was posted online via Health Affairs. The one minor deficit of the article is the use of the outdated term cardiac death. 

Deborah Verran's insight:

This article will be of interest in particular to health care professionals who have an interest in policy and regulatory frameworks pertaining to organ donation from deceased donor.

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Shameful organ-donation rates push Hong Kong to excel in transplant surgery

Shameful organ-donation rates push Hong Kong to excel in transplant surgery | Organ Donation & Transplant Matters Resources | Scoop.it

The challenges posed by Hong Kong's shamefully low organ-donation rate has inspired groundbreaking surgery in the city, but still hundreds die on transplant waiting lists.

 

Journalist Stuart Heaver investigates the cultural reluctance to saving strangers and what this has meant for the local transplant programmes, particularly the liver transplant unit. This detailed article can be viewed by clicking on the banner headline.

Deborah Verran's insight:

This detailed article will be of interest both to transplant professionals as well as  professionals who have an interest in the challenges faced by organ donation systems around the world.

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

Organ donor's reported ancestry depends on question format - Medical Xpress

Organ donor's reported ancestry depends on question format - Medical Xpress | Organ Donation & Transplant Matters Resources | Scoop.it

For years, medicine has relied on self-reported race/ethnicity as the basis of an array of decisions, from risk for disease to matching of organ and tissue donors with recipients.

 

However with the increasing recognition of the importance of genetic matching based on sophisticated bioinformatics particularly in bone marrow transplantation the validity of self reported race/ethnicity is now being called into question.

 

The results of research into this very topic have now been reported online and a summary of the research can be viewed by clicking on the banner headline.

Deborah Verran's insight:

For bone marrow transplantation close genetic matching between the donor and the recipient is essential, whereas for most types of solid organ transplantation (except for kidneys) this is not as critical.

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

First Bilateral Hand Transplant in a Child: Zion's Story - YouTube

This is the video about the world’s first bilateral hand transplant performed in young Zion Harvey (pictured above) at The Children’s Hospital of Philadelphia. For more: http://www.chop.edu/handtranspla...

 

An interview with the lead surgeon ( Dr L Scott Levin), provides a lot more detail on the planning and teamwork that was required in order for the procedure to even be contemplated. This can be accessed via the following Medscape link-

 

http://www.medscape.com/viewarticle/848727

 

Deborah Verran's insight:

Quality video which tells the story of Zion's journey through the transplant procedure

more...
No comment yet.
Scooped by Deborah Verran
Scoop.it!

The moral dilemma of organ donation in Egypt

The moral dilemma of organ donation in Egypt | Organ Donation & Transplant Matters Resources | Scoop.it

Egyptians in need of transplants face a choice between trying to source an organ from a live donor or if they have the financial means to try and source a transplant via other avenues.

 

Due to the political instability in Egypt despite the passage of legislation allowing organ donation to occur from deceased donors post declaration of brain death, there have been barriers to implementing this in practice. However progress has been made with respect to shutting down illegal organ trafficking operations.

Deborah Verran's insight:

This article provides an insight into the current challenges and barriers to organ donation in Egpt

more...
No comment yet.