Organ Donation & Transplant Matters Resources
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Organ Donation & Transplant Matters Resources
Combining reports, research findings and topic reviews
Curated by Deborah Verran
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Human-Animal Hybrid: Scientists Grow Human Cells Inside Pig Embryos

Human-Animal Hybrid: Scientists Grow Human Cells Inside Pig Embryos | Organ Donation & Transplant Matters Resources | Scoop.it

Scientists injected pig embryos with human stem cells to produce animal embryos that contain human cells. What are the dangers and potential benefits of this technology? This is explored in the full article which can be accessed via clicking on the banner headline.


This online article is the result of the publication of the findings of sophisticated laboratory research into the creation of embryos which contain cells from two different animals. In the research quoted above this involved placing genetically modified human stem cells into pig blastocysts (at the pre-embryo stage). Despite evidence of the human stem cells initially surviving there was limited evidence of them being present at the pig embryo stage as outlined in the full scientific report-


http://www.cell.com/cell/fulltext/S0092-8674(16)31752-4


Despite the headlines generated in some quarters by this particular research, this does not mean that the transplantation of organs from 'humanized pigs' is just around the corner as may have been implied.



Deborah Verran's insight:
This proof of concept study will now need to be followed by more sophisticated research in order to ascertain whether this will lead to so called humanized organs in pigs.
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NIH-funded researchers extend liver preservation for transplantation - EurekAlert (press release)

NIH-funded researchers extend liver preservation for transplantation - EurekAlert (press release) | Organ Donation & Transplant Matters Resources | Scoop.it

Reported online via EurekAlert is the news that NIH-funded researchers in the United States may have developed a new method for extending liver preservation for transplantation.

 

Transplants of skin, kidneys, hearts, lungs, corneas, and livers have become commonplace but due to a shortage of donor organs not all potential transplant recipients will receive a transplant in time.

 

Rat livers where able to be preserved for an extended period of time using a new super cooling method which is described in more detail in the report(click on banner headline).

 

For a more detailed report click on the following link to the NIH press release-

 

http://www.nih.gov/news/health/jun2014/nibib-30.htm

 

Deborah Verran's insight:

More research is now required to see whether this new process can be adapted for the cold preservation of human livers to allow for extended periods of storage prior to transplantation

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