Organ Donation & Transplant Matters Resources
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Organ Donation & Transplant Matters Resources
Combining reports, research findings and topic reviews
Curated by Deborah Verran
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John Oliver targets dialysis, a procedure that’s exhausting, deadly, and very profitable in the United States

John Oliver targets dialysis, a procedure that’s exhausting, deadly, and very profitable in the United States | Organ Donation & Transplant Matters Resources | Scoop.it

If you understand what is happening in some parts of the United States with patients who are undergoing dialysis then there is the opportunity for steps to be taken to improve the situation.


This includes the patients on dialysis understanding that their treatment options include a kidney transplant. Their family members also need to understand that there are treatment options. In addition members of the wider community can contribute by joining the organ donor registry and also informing their own relatives of this fact. 


The video footage can be viewed via the following link-

https://youtu.be/IDjEtF59Fiw


Deborah Verran's insight:
Dialysis services are frequently outsourced to companies in the United States. One provider comes in for extra scrutiny via this particular on air late night TV program. The video footage is worth watching.
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The truth about organ transport and transplantation in India

The truth about organ transport and transplantation in India | Organ Donation & Transplant Matters Resources | Scoop.it

There continues to be unmet challenges with respect to increasing the numbers of both organ donors as well as organ transplants in India. With there having been only 350 heart transplants conducted in the last 24 years in the country, there is room for improvement.


The current barriers to increasing the number of organ transplants includes the lack of established transplant units, lack of access due to financial restrictions for many patients and a lack of established transport systems ensuring the rapid delivery of organs between hospitals.


This article will be of interest to healthcare professionals who have an interest in organ donation as well as transplantation.

Deborah Verran's insight:
Increasing the numbers of organ donors as well as the numbers of organ transplants in India will require that concentrated efforts are made to deal with the current barriers.
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Charges brought against makers of dietary supplement linked to liver damage - PBS NewsHour

Charges brought against makers of dietary supplement linked to liver damage - PBS NewsHour | Organ Donation & Transplant Matters Resources | Scoop.it

A Dallas company that had been ordered to recall a dietary supplement pill because of links to liver damage has now been indicted along with several of its executives on charges that they intentionally mis-branded their products and then continued to sell them.

 

 This is a postscript to the chain of events involving a nutritional supplement marketed under the label OxyElite Pro which was associated with cases of acute liver failure, particularly within the United States. Some of the patients with acute liver failure subsequently required liver transplantation due to the severity of their medical condition.

Deborah Verran's insight:

A cautionary tale of a chain of events surrounding a nutritional supplement that failed to meet regulatory standards within the United States.

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Drugs produce high hepatitis C eradication rates, even in patients with liver disease

Drugs produce high hepatitis C eradication rates, even in patients with liver disease | Organ Donation & Transplant Matters Resources | Scoop.it

This is the latest report of success being achieved with new direct anti-viral drugs in the treatment of hepatitis C.

 

Two clinical trials of antiviral drug combinations report that 12-week courses are leading to effective viral eradication for a high percentage of patients with chronic hepatitis C infection.

 

To read more on the particular drugs involved and what the exact results were please click on the banner headline.

Deborah Verran's insight:

Further evidence of the efficacy of some of the new antiviral agents for treating chronic hepatitis C. It is hoped that eventually there will be less patients requiring liver transplantation for liver disease due to this particular virus.

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Frailty Tied to Lower Survival Rates After Kidney Transplant

Frailty Tied to Lower Survival Rates After Kidney Transplant | Organ Donation & Transplant Matters Resources | Scoop.it

Research findings have linked increased patient frailty at the time of kidney transplant surgery to an increased mortality rate. This has recently been published online in the American Journal of Transplantation which can be viewed via the following link-

http://au.wiley.com/WileyCDA/PressRelease/pressReleaseId-113402.html

 

 It is suggested by the researchers that doctors should monitor such patients closely after surgery.

Deborah Verran's insight:

At times decisions also have to be made to not proceed with kidney transplant surgery if patients are significantly physically deconditioned. Kidney transplant surgery is major surgery and is combined with the initiation of powerful immunosuppressive drug therapy. This sets this type of surgery apart from operations of a similar magnitude.

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Sofosbuvir taken before or after liver transplant reduces hepatitis C recurrence - aidsmap

Sofosbuvir taken before or after liver transplant reduces hepatitis C recurrence - aidsmap | Organ Donation & Transplant Matters Resources | Scoop.it

The new anti-viral agent Sofosbuvir taken either before or after liver transplant reduces hepatitis C recurrence as reported via aidsmap.

 

An interferon-free combination of sofosbuvir plus ribavirin administered before liver transplantation prevented hepatitis C recurrence in nearly

two-thirds of cases as recently reported at the AASLD meeting.

 

Sofosbuvir is just one of a number of new anti-viral oral agents that are being trialled for the treatment of hepatitis C (as pictured in the graphic). Hence this is an encouraging report.

 

The combination of Sofosbuvir with a different anti-viral agent Ledipasvir is reported via the Guardian (post publication in The Lancet )-

 

http://www.theguardian.com/science/2013/nov/05/hope-hepatitis-cure-drugs-success-sofosbuvir-ledipasvir?CMP=twt_gu

 

 

Deborah Verran's insight:

Hepatitis C will become a treatable condition. Ongoing tirals mean that more reports will follow on this topic and treatment options will become clearer.

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A Potential Passport for Care Coordination: Healthcare Informatics Magazine

A Potential Passport for Care Coordination: Healthcare Informatics Magazine | Organ Donation & Transplant Matters Resources | Scoop.it

Want to read about an innovative approach for co-ordinating care for patients involving the use of information technology? This report comes from the United States.

 

Via Healthcare Informatics Magazine | Health IT | Information Technology,Health care information technology & IT strategy news for CIOs, CMIOs & clinical informaticists. Also learn about EMR EHR, ARRA HITECH, wireless technologies & meaningful use policy.

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Busiest ever year for organ donation in Scotland

Busiest ever year for organ donation in Scotland | Organ Donation & Transplant Matters Resources | Scoop.it

In news from authorities in Scotland it has been confirmed that the organ donation rate has increased over the last year. 


With the figures for 2016/17 revealing a 34% increase in the number of organ donors in Scotland, this has led to a record number of organ transplants being performed.


One woman (Heather Marshall, pictured above) who was interviewed for this story, describes how undergoing a liver transplant has turned her life around.

Deborah Verran's insight:
Important news out of Scotland with the rate of organ donation now being close to the 25 per million mark
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Culture of silence protected disgraced trachea surgeon

Culture of silence protected disgraced trachea surgeon | Organ Donation & Transplant Matters Resources | Scoop.it

An independent report has found both serious medical inadequacies and an uncritical environment surrounding Dr Paolo Macchiarini whilst he was heading the trachea transplant programme at the Karolinska Institute in Sweden.


In the final chapter of a story that has been attracting media attention for several years the report of the external review has now been released.


The lack of appropriate governance for this particular research programme combined with a lack of medical leadership is clearly  evident.


For the full story click on the banner headline..

Deborah Verran's insight:
Sobering report which shines a light on the inadequate governance processes which surrounded this particular clinical research programme. 
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Inequality in US organ transplants: Researchers detail how the wealthy leverage the opportunity of being allowed on to multiple lists

Inequality in US organ transplants: Researchers detail how the wealthy leverage the opportunity of being allowed on to multiple lists | Organ Donation & Transplant Matters Resources | Scoop.it

It appears that in the United States patients who are financially well off are able to leverage a loop hole in the organ donation system. That is they are able to be on multiple waiting lists for an organ transplant.

 

As revealed by research that was recently presented at a medical scientific meeting, patients who were on wait lists at multiple centers had higher transplant rates. The reasons for this are explored further in the online article which can be viewed by clicking on the banner headline.

Deborah Verran's insight:

A unique loophole in the United States organ donation system provides patients who are well with the opportunity to be listed on more than one transplant centre's waiting list.

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Inside the hospitals performing thousands black market organ transplant procedures

Inside the hospitals performing thousands black market organ transplant procedures | Organ Donation & Transplant Matters Resources | Scoop.it

In India, where these pictures were taken, around 2,000 people are thought to illegally sell their kidneys each year on the black market. This article exposes this practice and provides some estimates on how many of these type of procedures may be being performed per year internationally.

 

The language used to describe the conditions in some of the hospitals where these particular surgeries are being undertaken is not mild. For further information click on the banner headline.

Deborah Verran's insight:

More evidence of what happens when desperate patients link up with desperate individuals who are prepared to sell their own organs with brokers acting as the so called 'middle men'.

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How Apple CEO Steve Jobs got the liver he needed in Memphis

How Apple CEO Steve Jobs got the liver he needed in Memphis | Organ Donation & Transplant Matters Resources | Scoop.it

This story from the United States of America outlines how ex Apple CEO Steve Jobs was able to get a liver transplant by seeking to improve his odds of receiving a donor liver.


However as becomes apparent in the article other patients are also seeking to try and improve their odds and this can involve moving interstate if they are in a position to do so. Not all are successful however, which is a direct result of the large number of patients waiting for what are a scarcer number of donor livers.

Deborah Verran's insight:

Harsh realities of waiting for a liver transplant within the United States

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Artificial Wearable Lung to Help Patients be Mobile Before Transplant - Medgadget.com

Artificial Wearable Lung to Help Patients be Mobile Before Transplant - Medgadget.com | Organ Donation & Transplant Matters Resources | Scoop.it

Reported via Medgadget.com
Research into an artificial Wearable Lung to help patients be mobile prior to lung transplantation. 
 
Patients preparing for a lung transplant often end up bedridden for extended periods of time while awaiting surgery. Hence any advance in technology which could potentially extend the period patients wait whilst allowing them to remain mobile is very important.

 

This is a preliminary report of a device which will need to be trialled on patients.

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