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Organ Donation & Transplant Matters Resources
Combining reports, research findings and topic reviews
Curated by Deborah Verran
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Pitt-UPMC exploring way to keep donated livers viable longer via machine preservation

Pitt-UPMC exploring way to keep donated livers viable longer via machine preservation | Organ Donation & Transplant Matters Resources | Scoop.it

Livers and other organs begin lacking oxygen the moment they are removed from the organ donor and hence may have sustained damage by the time a transplant occurs.

 

In cases where the circulation to the liver has ceased for a period of time prior to its removal from the organ donor, the damage to the liver can be greater.

 

This report outlines the use of a liver preservation machine that was initially developed in Europe as part of ongoing research efforts into the optimal method of preserving donor livers. To read more on this story click on the banner headline.

Deborah Verran's insight:

The preservation machine featured in this article is one of two that have initially been developed in Europe. It is now being used in preliminary trials by some liver transplant programmes around the world. Data on liver transplant outcomes utilizing this technology are expected to be available in another 1-2 years. 

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Study reports liver donors face mortality risk with LDLT - from News-Medical.Net - News-Medical.net

Study reports liver donors face mortality risk with LDLT - from News-Medical.Net - News-Medical.net | Organ Donation & Transplant Matters Resources | Scoop.it

Published Study reports that live liver donors face a mortality risk with LDLT  A study published in Liver Transplantation, a journal of the American Association for the Study of Liver Diseases and the International Liver Transplant Society has revealed what are the current estimated risks for morbidity and mortality with adult live liver donation...

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Declining liver utilization for transplantation in the United States and the impact of donation after cardiac death - Orman - 2012 - Liver Transplantation - Wiley Online Library

Declining liver utilization for transplantation in the United States and the impact of donation after cardiac death - Orman - 2012 - Liver Transplantation - Wiley Online Library | Organ Donation & Transplant Matters Resources | Scoop.it

This retrospective analysis of registry data in the United States has revealed that there has been a recent drop in the supply of quality livers from deceased donor organ donors: http://t.co/XRv8zWYJ

 

There are four factors associated with non-use of the donor liver for transplantation and these are-donation after cardiac death pathway, donor Body Mass Index(a marker for obesity), older donor age and the presence of diabetes.

 

Important point if the donor liver is not retrieved for transplantation it is not 'thrown away'( as reported)-

http://www.foxnews.com/health/2013/01/11/study-finds-increase-in-unused-transplant-livers/

 

 

There are policies and procedures in place within the United States for the differing scenarios where the various deceased donor organs are not able to be transplanted.

Deborah Verran's insight:

Important data, variably reported. Cross posted onto http://scoop.it/t/organ-donation-transplant-matters

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India has addressed blood donation, it must now do the same with organ donation

India has addressed blood donation, it must now do the same with  organ donation | Organ Donation & Transplant Matters Resources | Scoop.it

This detailed article outlines the multiple factors which contribute to an unmet need for organ donation within India.

 

Although living kidney and living liver transplantation are both performed, these are costly procedures and hence only available to those who can afford to pay.

 

A similar perspective from Dr Avnish Seth, the Director of Fortis Organ Retrieval & Transplant can be viewed via the following link-

http://blog.organdonationday.in/?p=30

 

 

Deborah Verran's insight:

There remain challenges within India with respect to establishing a robust system for deceased donor organ donation across the country

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FDA Approves FibroScan(R) For Non-Invasive Liver Diagnosis

FDA Approves FibroScan(R) For Non-Invasive Liver Diagnosis | Organ Donation & Transplant Matters Resources | Scoop.it

Reported via Medical News Today. Echosens(TM) is pleased to announce that the FibroScan(R) device has received 510(k)clearance from the U.S. Food and Drug Administration (FDA) for use as a non-invasive method of  liver imaging.

 

The device is already in use in some parts of the world but penetrating the US market is now a significant development.

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