Organ Donation & Transplant Matters Resources
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Organ Donation & Transplant Matters Resources
Combining reports, research findings and topic reviews
Curated by Deborah Verran
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Ministerio de Salud suspendió programa de trasplante renal in Venezuela

Ministerio de Salud suspendió programa de trasplante renal in Venezuela | Organ Donation & Transplant Matters Resources | Scoop.it

Ministerio de Salud suspendió programa de trasplante renal


It has been confirmed that the Ministry of Health in Venezuela has suspended deceased donor organ donation as well as renal transplantation effective the 1st of June 2017.


This follows on from months of critical shortages of pharmaceutical agents including in particular the immunosuppressive drugs Tacrolimus and Mycophenolate Mofetil which are two of the medications most commonly prescribed to transplant recipients.


This comes on top of an increasing number of reports of adverse health outcomes in Venezuela as the health care system struggles to deliver services in the face on increasing shortages of consumable items as well as medications.


The online article includes the forceful response from the Venezuelan society of Nephrology



Deborah Verran's insight:
Patients with end stage kidney disease in Venezuela are running out of options. Humanitarian assistance will be required to support the Venezuela healthcare system in the short to medium term.
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What Happens When A Living Kidney Donor Needs A Transplant in the United States?

What Happens When A Living Kidney Donor Needs A Transplant in the United States? | Organ Donation & Transplant Matters Resources | Scoop.it
A new study from the United States examines how well the system works to prioritize the needs of previous live kidney donors if they end up needing a kidney transplant of their own.

Live kidney donors can receive priority for a kidney transplant if it is determined that their remaining kidney is failing. However it seems that this information may not be fully understood across the healthcare system within the United States.


Hence the importance of this retrospective review of just over 200 live kidney donors. For more information click on the banner headline.
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Kidney donor’s death a ‘nightmare scenario’ for UCSF program

Kidney donor’s death a ‘nightmare scenario’ for UCSF program | Organ Donation & Transplant Matters Resources | Scoop.it

News from the United States that the University of California San Francisco (UCSF) has suspended its live donor kidney transplant program whilst an investigation is carried out into the recent death of a live donor following surgery.  

 

UCSF’s suspension of its living donor program for kidney transplants this week after the death of a donor highlights a rare but potential complication for a procedure that’s typically an altruistic gift by a friend or family member to a patient who requires a kidney transplant.

 

For more on this story click on the banner headline....

Deborah Verran's insight:

A reminder that live kidney donation involves major surgery both for the donor as well as the recipient and hence is not risk free.

 

Results of the investigation into the death of this particular donor are now awaited

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Early Stanford live kidney donor dies aged 99 years

Early Stanford live kidney donor dies aged 99 years | Organ Donation & Transplant Matters Resources | Scoop.it

One of Stanford hospitals first living kidney donors lived a long and fulfilling life with her family until her death in April 2015.

 

In 1965 Inga Goodnight donated a kidney to her young son Gary Goodnight (picture above years later). Despite the fact that Inga was only the third live kidney donor in the Stanford hospitals renal transplant programme, the transplant procedure undertaken in 1965 was a success.

 

Inga went on to live a full life and more on both her and Gary's stories can be accessed by clicking on the banner headline.

Deborah Verran's insight:

An interesting story of one of early live kidney donors in the United States and how the transplant procedure allowed her son to live well into adulthood.

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Desperately needed organs from anonymous living donors are saving lives but raise ethical concerns

Desperately needed organs from anonymous living donors are saving lives but raise ethical concerns | Organ Donation & Transplant Matters Resources | Scoop.it

The National Post in Canada was recently invited to document one woman's altruistic living kidney donation — an act that still generates controversy and is even banned in some U.S. hospitals. In the process an exploration was undertaken to also explore some of the ethical issues around altruistic live organ donation which contribute to the reluctance of some transplant hospitals to offer this service.

 

Concerns over the safety and the long term well being of a live organ donor who is not related in any way to the transplant recipient have helped contribute to the high degree of caution around this process.

 

The live donor featured in this article is interviewed along with members of her surgical team as well as other health professionals with expertise in the assessment of live organ donors. The full text of this interesting article can be viewed by clicking on the banner headline.

Deborah Verran's insight:

A well written article that will be of interest to anyone with an interest in live organ donation

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How Much for a Kidney? Should live donors be compensated?

How Much for a Kidney? Should live donors be compensated? | Organ Donation & Transplant Matters Resources | Scoop.it

How best to encourage and support organ donation is the subject of an this online series of articles which debate this topic.


Titled How Much for a Kidney? the series is published via the New Yprk Times and focuses on kidney transplantation. 

 

According to the World Health Organization, 80,000 kidney transplants are performed worldwide each year, yet the demand now out strips the supply of donor kidneys.

 

To access the series of articles, click on the banner headline.

 

To read the article on why the testing of well thought out incentives for organ donation now needs to be considered click on the following link-

http://www.nytimes.com/roomfordebate/2014/08/21/how-much-for-a-kidney/test-incentives-for-organ-donations-theres-no-reason-not-to

 

Deborah Verran's insight:

Polished, professional series of viewpoints on how best to increase organ donation published via the New York Times

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Ethical dilemmas surround those willing to sell, buy kidneys on black market - CBS News

Ethical dilemmas surround those willing to sell, buy kidneys on black market - CBS News | Organ Donation & Transplant Matters Resources | Scoop.it

This article outlines the ethical dilemmas that surround those willing to sell, and buy kidneys on the black market and is posted online via
CBS News in the United States.

 
There's no denying that there is a shortage of organ donations in the United States and that this leads to some individuals looking to 'buy a kidney'. However what is less well known are some of the risks with this approach as well as the downsides.

 

The article is in advance of a programme on this topic which will air via HBO in the United States in November. However for those who are interested there is a short video of an interview held with ethicist Arthur Kaplan on the topic of paying live kidney donors.

Deborah Verran's insight:

This will be of interest to healthcare professionals associated with both live and deceased donor organ donation programmes

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Official: Kidney for Ohio Transplant Put in Trash

Official: Kidney for Ohio Transplant Put in Trash | Organ Donation & Transplant Matters Resources | Scoop.it

Part of the organ donation process includes packaging of the organs for subsequent transplantation into recipients. There are usually defined procedures and systems in place encompassing all donor scenarios. Tnis is important in order to both ensure and maintain quality as well as mitigate against possible errors.

 

This brief report out of the USA details an incident where a kidney was discarded due to human error. A health commissioner says a nurse accidentally disposed of a kidney from a living donor at an Ohio hospital that later suspended its kidney transplant program.

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The Relationship Between Social Media and Organ Donation? It’s Complicated.

The Relationship Between Social Media and Organ Donation? It’s Complicated. | Organ Donation & Transplant Matters Resources | Scoop.it

Some surgeons worry that the ease of Facebook entreaties particularly to save the lives of some transplant recipients, might inspire potential organ donors to make their decisions too lightly.


As outlined in this article, one transplant center in the United States suddenly found themselves under enormous pressure to field hundreds of enquiries from potential organ donors. This occurred after a Facebook post that was made by the parent of a sick child went viral.


Apart from dealing with the actual volume of calls and other expressions of interest, the initial problem faced by the transplant center was how to come up with a short list of suitable potential donors. This was followed by how to deal with all of the other expressions of interest, for which one solution was to request that people make contact with other not for profit organizations/stakeholders on how best to proceed.

Deborah Verran's insight:
A good description of some of the issues that can arise if a social media campaign for a live organ donor goes viral.
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Iran’s cash-for-kidney programme not without controversy

Iran’s cash-for-kidney programme not without controversy | Organ Donation & Transplant Matters Resources | Scoop.it

Iran’s kidney  transplant programme stands apart from other organ donation systems around the world by openly allowing payments, typically of several thousand dollars to live kidney donors.


Although there is some oversight of the relevant processes including at the level of the hospitals, where this particular programme attracts international concern is whether the financial payment acts as an inducement to live kidney donors.


For more on this story click on the banner headline.

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Lanie Ross - When Altruism Goes Awry: Live Kidney Donors in End Stage Renal Disease

This lecture titled 'When Altruism Goes Awry: Living Kidney Donors in End Stage Renal Disease' was delivered via Lanie Ross, MD, University of Chicago November 13, 2015 

 

It explores what is known about live kidney donors who have gone on to develop end stage renal failure within the United States. It also outlines the current limitations of registry data and how this may be improved.

Deborah Verran's insight:

This talk will be of interest to healthcare professionals with a role in the oversight and management of living kidney donation.

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Surgeon describes first skull and scalp transplant, Newshour - BBC World Service

Surgeon describes first skull and scalp transplant, Newshour - BBC World Service | Organ Donation & Transplant Matters Resources | Scoop.it

Surgeon Michael Klebuc describes the operation that was required to replace Jim Boysen's skull and scalp.

 

Dr Klebuc also describes the challenges with sourcing the appropriate size matched and colour matched composite tissue graft that was used to partially replace this patients own skull and scalp. The audio can be accessed via clicking on the banner headline.

 

A more detailed online report of the planning that was required as well as the conduct of the surgery and the aftercare of this patient can be accessed via the following link-

http://www.washingtonpost.com/news/morning-mix/wp/2015/06/05/texas-man-gets-worlds-first-skull-and-scalp-transplant-plus-a-new-kidney-and-pancreas/

 

Deborah Verran's insight:

This patient underwent both a composite tissue transplant as well as a combined kidney-pancreas solid organ transplant. This required the co-operation of multiple surgical teams as well as rigorous attention to both planning and undertaking the surgical procedure.

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New US kidney allocation rules give hope to people waiting for donated kidneys

New US kidney allocation rules give hope to people waiting for donated kidneys | Organ Donation & Transplant Matters Resources | Scoop.it

This last week a number of new rules around the allocation of deceased donor kidneys have come into place within the United States.

 

The new rules change the way that organ allocation now occurs for people waiting for a new kidney. It includes a formula which allows for longevity matching of the donor kidneys with potential recipients. Doctors hope that this new allocation system will now maximize the outcomes of transplanting these relatively scarce donor organs.

 

The media release from the United Network of Organ Sharing (UNOS) can be viewed via the following link-

http://www.unos.org/about/index.php?topic=newsroom&article_id=2897

 

Deborah Verran's insight:

This represents major change to the kidney allocation algorithms within the United States with the aim of achieving better patient outcomes.

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India has addressed blood donation, it must now do the same with organ donation

India has addressed blood donation, it must now do the same with  organ donation | Organ Donation & Transplant Matters Resources | Scoop.it

This detailed article outlines the multiple factors which contribute to an unmet need for organ donation within India.

 

Although living kidney and living liver transplantation are both performed, these are costly procedures and hence only available to those who can afford to pay.

 

A similar perspective from Dr Avnish Seth, the Director of Fortis Organ Retrieval & Transplant can be viewed via the following link-

http://blog.organdonationday.in/?p=30

 

 

Deborah Verran's insight:

There remain challenges within India with respect to establishing a robust system for deceased donor organ donation across the country

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Ferritin plays central role in kidney damage by controlling iron - UAB News

Ferritin plays central role in kidney damage by controlling iron - UAB News | Organ Donation & Transplant Matters Resources | Scoop.it

It appears that Ferritin plays central role in kidney damage by controlling iron as reported via UAB News. In a research model a protein known as, ferritin, appears to protect the kidneys against a damaging after-effect of injury, heart failure or hardened arteries by controlling levels of iron, according to this research study...

Deborah Verran's insight:

Untangling the role of iron in the kidney, more complex than previously believed

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