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Organ Donation & Transplant Matters Resources
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FDA Panel Favors Device to Boost Lung Transplant Success - MedPage Today

FDA Panel Favors Device to Boost Lung Transplant Success - MedPage Today | Organ Donation & Transplant Matters Resources | Scoop.it

The news has come that an FDA Panel has given the approval for a normothermic lung preservation device to continue to be used in clinical research in order to boost lung transplant success as reported via MedPage Today.

 

A Canadian center involved in the HELP trial increased the proportion of donated lungs actually transplanted from 25% to 36% after starting to use the EXVIVO lung perfusion device. Of note there remains limited data for the medium to long term outcomes of lungs that have been transplanted after being preserved using this particular device. 

Deborah Verran's insight:

News that the EXVIVO lung preservation device has  received a preliminary limited approval by the FDA in the United States (humanitarian use device exemption)

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Re-conditioning lungs for transplant UK trial of ex-vivo lung preservation

Re-conditioning lungs for transplant UK trial of ex-vivo lung preservation | Organ Donation & Transplant Matters Resources | Scoop.it

News out of the United Kingdom (UK) this week is that UK transplant centres are set to trial a technique which re-conditions lungs retrieved from organ donors to improve the lungs ability to function.

 

Although initially reported as "lung washing" this is actually ex-vivo lung preservation. Circulating oxygen and a balanced preservation fluid through the lungs following the surgical retrieval may help improve their condition. "Reconditioned lungs" may then be able to be transplanted into recipients such as the woman featured in this news release.

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UCLA performs first 'breathing lung' transplant in United States - EurekAlert (press release)

The first lung transplant has been performed in the United States where the TransMedics organ preservation device was utilised.  The procedure occurred at the University of California Los Angeles and has been termed a 'breathing lung' transplant  due to the manner in which organ preservation is achieved.

 

Further specific information can be sourced via

http://www.medlatest.com/2012/11/28/ucla-performs-breathing-lung-transplant-united-states/

 

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