Organ Donation & Transplant Matters Resources
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Organ Donation & Transplant Matters Resources
Combining reports, research findings and topic reviews
Curated by Deborah Verran
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TransMedics Announces The World's First Human Liver Transplantation Using The Organ Care System (OCS™) Liver Technology & The Initiation of The OCS™ Liver PROTECT U.S. Pivotal Trial: TransMedics, Inc.

TransMedics Announces The World's First Human Liver Transplantation Using The Organ Care System (OCS™) Liver Technology & The Initiation of The OCS™ Liver PROTECT U.S. Pivotal Trial: TransMedics, Inc. | Organ Donation & Transplant Matters Resources | Scoop.it

TransMedicsInc announces the transplantation of the first human liver using the #OCSLiver ex-vivo preservation device as well as initiation of the multicentre prospective PROTECT trial.

 

For more information click on the banner headline

Deborah Verran's insight:

This is one of at least three ex-vivo liver preservation devices now in trial around the world. The outcome data are awaited with interest noting that the benefits of ex-vivo liver preservation will need to be clear for this type of technology to be incorporated into routine practice.

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Pitt-UPMC exploring way to keep donated livers viable longer via machine preservation

Pitt-UPMC exploring way to keep donated livers viable longer via machine preservation | Organ Donation & Transplant Matters Resources | Scoop.it

Livers and other organs begin lacking oxygen the moment they are removed from the organ donor and hence may have sustained damage by the time a transplant occurs.

 

In cases where the circulation to the liver has ceased for a period of time prior to its removal from the organ donor, the damage to the liver can be greater.

 

This report outlines the use of a liver preservation machine that was initially developed in Europe as part of ongoing research efforts into the optimal method of preserving donor livers. To read more on this story click on the banner headline.

Deborah Verran's insight:

The preservation machine featured in this article is one of two that have initially been developed in Europe. It is now being used in preliminary trials by some liver transplant programmes around the world. Data on liver transplant outcomes utilizing this technology are expected to be available in another 1-2 years. 

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Proceed II International Heart Transplant Trial Results Revealed at ISHLT 34th ... - PR Web (press release)

Proceed II International Heart Transplant Trial Results Revealed at ISHLT 34th ... - PR Web (press release) | Organ Donation & Transplant Matters Resources | Scoop.it

The Proceed II International Heart Transplant Trial Results are being Revealed at the ISHLT 34th meeting.

 

Preliminary outcome data are favorable for heart transplant outcomes where donor hearts were maintained on the TransMedics Organ Care System device compared to being placed into conventional cold storage prior to transplantation.

 

Further comments from medical professionals on this new technology can be viewed via this link-

http://www.inquisitr.com/1207466/transporting-a-heart-in-a-box-is-a-great-advance-says-dr-mark-plunkett/

 

Deborah Verran's insight:

Promising preliminary results with the use of ex-vivo normothermic heart preservation

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Europe's first heart transplant from a donation after circulatory death organ donor

Europe's first heart transplant from a donation after circulatory death organ donor | Organ Donation & Transplant Matters Resources | Scoop.it

Surgeons at the Papworth hospital in Cambridgeshire, the United Kingdom have performed the first successful heart transplant in Europe using a heart retrieved from a donation after circulatory death (DCD) organ donor.

 

 Importantly the heart was placed on the TransMedics organ Care System device (pictured), following its removal from the deceased donor. This allowed for an assessment to be made as to the suitability of the heart to then be transplanted. A video which includes footage of the man who received the donor heart can be accessed by clicking on the banner headline.

 

This follows on from the report from Australia of two successful heart transplants from DCD organ donors in 2014 http://sco.lt/7Z57IX

 

Deborah Verran's insight:

News that a second heart transplant programme has successfully transplanted the heart from a DCD organ donor

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'Heart in a box': Pioneering device keeps donor organs alive OUTSIDE the body

'Heart in a box': Pioneering device keeps donor organs alive OUTSIDE the body | Organ Donation & Transplant Matters Resources | Scoop.it


Traditionally, all donor organs are placed in a cool-box and surrounded by ice to prevent them deteriorating on their journey between hospitals.

 

However new technology in the form of transportable machines is

leading to changes in how some organs are maintained following their removal from the donor.

 

This report focuses on the preliminary experience with the use of normothermic machine preservation in the Harefield heart transplant programme in the United Kingdom

Deborah Verran's insight:

Another report on the preliminary use of machine preservation in heart transplantation. Further data from the prospective clinical trials that are currently being undertaken is now awaited

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Set Of Donor Lungs Preserved For 11 Hours Outside The Body - RedOrbit

Set Of Donor Lungs Preserved For 11 Hours Outside The Body - RedOrbit | Organ Donation & Transplant Matters Resources | Scoop.it

Reported via RedOrbit- Set Of Donor Lungs Preserved For 11 Hours Outside The Body.

 

The multidisciplinary transplant team at University Hospitals Leuven in Belgium successfully preserved a set of donor lungs for over eleven hours with the help of a machine, the. Organ Care Systems (OCS) device.

 

In this unusual case a combined liver and lung transplant procedure was required to deal with a patient with both acute liver failure and end stage lung disease. To facilitate the lung transplant being performed following the liver transplant procedure, the lungs required prolonged ex-vivo preservation via the OCS device.

Deborah Verran's insight:

One of an increasing number of cases where the OCS device is being used for ex-vivo lung preservation

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