Organ Donation & Transplant Matters Resources
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Organ Donation & Transplant Matters Resources
Combining reports, research findings and topic reviews
Curated by Deborah Verran
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A patient has 'caught' a kiwi fruit allergy from a bone marrow transplant

A patient has 'caught' a kiwi fruit allergy from a bone marrow transplant | Organ Donation & Transplant Matters Resources | Scoop.it
This is the first proof that this particular type of transplant procedure can lead to the spread of specific food allergies from the donor to the recipient. The fact that the allergy developed in the recipient reflects transmission of the cells responsible for the immune response that underpins the particular allergy in question.

Similar cases have been reported on occasion in liver transplant recipients.
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Simple steps can safeguard against Ebola transmission through organ donation in the United States

Simple steps can safeguard against Ebola transmission through organ donation in the United States | Organ Donation & Transplant Matters Resources | Scoop.it

While serious infections can be transmitted from donated organs, the risk of passing Ebola virus disease from an organ donor to a recipient is extremely small.

 

This is the conclusion reached by researchers in the United States in a recent editorial published in the American Journal of Transplantation.

 

As there is no readily available blood test available in all regions which could provide a rapid answer to whether or not a potential organ donor was harboring Ebola a safer strategy is to rely on the donors' recent history.

Deborah Verran's insight:

Steps are being taken within the United States to put safeguards in place across the organ donation system to prevent Ebola transmission occurring.

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New proposal for the better allocation of donated livers in transplants

New proposal for the better allocation of donated livers in transplants | Organ Donation & Transplant Matters Resources | Scoop.it

Researchers at the University of Cordoba (Spain) have developed a system that measures compatibility between donors and the most serious receivers in liver transplants. 

 

This takes into account over 30 donor and recipient variables from a retrospective analysis of over 1,000 liver transplant procedures,

 

However as yet the new algorithm has not been prospectively validated. 

 

Click on the banner headline to read more about the research.

Deborah Verran's insight:

The matching of donor livers to recipients involves that a number of both donor as well as recipient variables be taken into consideration. Apart from blood group matching, size matching of the donor organ to the recipient as well as undertaking a risk assessment of the outcome of the planned transplant procedure are all important in practice.

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New Bio-Sensors May Save Lung Transplant Patients from Organ Failure

New Bio-Sensors May Save Lung Transplant Patients from Organ Failure | Organ Donation & Transplant Matters Resources | Scoop.it

In the future a new system of sub classifying donor lungs, based on molecular profiling, could make more donor lungs available for transplantation purposes. 

 

This report is of new research on using a molecular probe in order to detect whether donor lungs may be at risk of poor early function following transplantation .

 

This is the first step in the use of this very modern technology in order to provide this particular type of extra information which can be used to assist with making decisions on whether donor lungs are suitable for transplantation. In addition the information may also be used to subclassify the donor lungs into whether they are considered normal or high risk organs for initial poor graft function following transplantation. More on this story can be viewed by clicking on the banner headline

Deborah Verran's insight:

This new molecular probe type of technology will need to be subjected to further trials so that a clearer picture can be gained of both its accuracy and validity 

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New Stanford blood test identifies heart-transplant rejection earlier than conventional biopsy - Stanford Medical Center Report

New Stanford blood test identifies heart-transplant rejection earlier than conventional biopsy - Stanford Medical Center Report | Organ Donation & Transplant Matters Resources | Scoop.it

Reported online via the Stanford Medical Center Report the news that
a blood test can identify heart-transplant rejection at an earlier stage than a conventional biopsy (as pictured).

 

The test detects of circulating donor DNA in the blood of heart transplant recipients. As this is a preliminary report more experience needs to be gained with this test prior to it becoming a possible addition to the current laboratory testing that is used to help monitor transplant recipients.

Deborah Verran's insight:

The next phase in the investigation of 'biomarkers' that will assist in the management of heart transplant recipients

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