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Organ Donation & Transplant Matters Resources
Combining reports, research findings and topic reviews
Curated by Deborah Verran
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Kidney transplant breakthrough may revolutionize life for organ recipients - Al Jazeera America

Kidney transplant breakthrough may revolutionize life for organ recipients - Al Jazeera America | Organ Donation & Transplant Matters Resources | Scoop.it

This new Kidney transplant breakthrough may revolutionize life for organ recipients if the procedure is shown to be both effective and durable as reported via Al Jazeera America.


By resetting the immune systems of kidney transplant patients, this new scientific clinical protocol could help prevent organ rejection without the need for long term expensive immunosuppressive medications.

 

The report focuses on the.current clinical research protocol being undertaken at NorthWestern University in Chicago where combined haematopoietic stem cell and live donor kidney transplantation are being performed on selected recipients.

Deborah Verran's insight:

Preliminary phases of an interesting clinical research protocol where further middle to longer term results are awaited

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Study suggests breakthrough in organ transplants

Study suggests breakthrough in organ transplants | Organ Donation & Transplant Matters Resources | Scoop.it

This recent news report of a pilot study in renal transplantation summarises how by infusing selected donor bone marrow cells as well as performing a kidney transplant, 5 out of 8 patients were able to be weaned off immunosuppression for a prolonged period of time.

 

Of note the kidney transplants were all from live donors, and the recipient's had to undergo extra treatment's in order to receive the infusion of the especially prepared cells.

 

Patients who are lucky enough to get a transplant for a failed organ usually face a lifetime on anti-rejection drugs [immunosuppression], which are expensive, have undesirable side effects and are not always effective. Hence although it seems promising, the results from this report will need to be replicated in larger prospective clinical trials in order for this type of regimen to be more widely adopted into practice.

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