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Rescooped by Stefan M Cooper Jr from New drug approvals
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Oxindole as starting material in organic synthesis

Oxindole as starting material in organic synthesis | Org Chem | Scoop.it
Oxindole as starting material in organic synthesis (13-8074LR) Arkivoc 2013 Part (i): Special Issue 'Reviews and Accounts' [pp. 470-535] Full Text: PDF (1,621K)   ,,,,,,,,,,,,,,,,,,,,,,free access ...

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Rescooped by Stefan M Cooper Jr from Natural Products Chemistry Breaking News
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The Emergence of the Structure of the Molecule and the Art of Its Synthesis

The Emergence of the Structure of the Molecule and the Art of Its Synthesis | Org Chem | Scoop.it

At the core of chemistry lie the structure of the molecule, the art of its synthesis, and the design of function within it. This Essay traces the understanding of the structure of the molecule, the emergence of organic synthesis, and the art of total synthesis from the 19th century to the present day.

 

Prof. Dr. K. C. Nicolaou

Angewandte Chemie International Edition

Article first published online: 3 DEC 2012

DOI: 10.1002/anie.201207081


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The sultan of synthesis - Chemistry World

The sultan of synthesis - Chemistry World | Org Chem | Scoop.it
Chemistry World The sultan of synthesis Chemistry World 'Nothing really inspired me until chemistry came along – it was love at first sight.' This love affair has consumed US chemist Phil Baran of the Scripps Research Institute in La Jolla,...
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Rescooped by Stefan M Cooper Jr from Natural Products Chemistry Breaking News
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Merging Chemical Synthesis and Biosynthesis: A New Chapter in the Total Synthesis of Natural Products and Natural Product Libraries

Merging Chemical Synthesis and Biosynthesis: A New Chapter in the Total Synthesis of Natural Products and Natural Product Libraries | Org Chem | Scoop.it

Natural product synthesis is a stressful task. Exploiting the understanding of biosynthetic pathways and implementing genetic engineering into the synthetic chemist’s portfolio paves the way for new alternatives for natural product synthesis. This Minireview describes “hybrid” strategies of organic synthesis and biosynthesis that result in facile access to complex natural products and libraries based on them.


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