Digital Optical Biopsy
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Digital Optical Biopsy
Eliminating diagnostic and treatment uncertainties with real-time digital in vivo microscopy and AI-based assisted-interpretation
Curated by Sacha Loiseau
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Interview with Dr Bertrand Napoléon Confocal Laser Endomicroscopy

Interview with Dr Bertrand Napoléon Confocal Laser Endomicroscopy | Digital Optical Biopsy | Scoop.it
Dr Bertrand Napoléon Confocal Laser Endomicroscopy (CLE) is helping prevent certain pancreatic cancers
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Webinar recording by Mauna Kea Technologies: In vivo cancer imaging

In vivo cancer imaging: monitor the tumor and its microenvironment at cellular resolution. Learn about cutting-edge research using Cellvizio Lab from Maun
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Barrow research focuses on use of new technology for imaging brain tumors

Barrow research focuses on use of new technology for imaging brain tumors | Digital Optical Biopsy | Scoop.it
Scientists at Barrow Neurological Institute have recently made discoveries about use of a new technology for imaging brain tumors in the operating room -- a finding that could have important implications for identifying and locating invading cells...
Sacha Loiseau's insight:
CLE for neurosurgery is ... a no-brainer ! There is great adequacy between the needs and the answers provided by real time microscopy in the brain. 
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Mauna Kea Technologies Announces Cook Medical's Introduction of the Cellvizio Platform at the American Urological Association Annual Meeting

Mauna Kea Technologies Announces Cook Medical's Introduction of the Cellvizio Platform at the American Urological Association Annual Meeting | Digital Optical Biopsy | Scoop.it
PARIS, May 9, 2016 /PRNewswire/ -- Mauna Kea Technologies Announces Cook Medical's Introduction of the Cellvizio Platform at the America
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In vivo assessment of tumour angiogenesis in colorectal cancer: Role of confocal laser endomicroscopy - De Palma - Colorectal Disease - Wiley Online Library

In vivo assessment of tumour angiogenesis in colorectal cancer: Role of confocal laser endomicroscopy - De Palma - Colorectal Disease - Wiley Online Library | Digital Optical Biopsy | Scoop.it

Aim
Tumour neoangiogenesis is a key factor for tumour progression and metastatic spread. The possibility to assess tumour angiogenesis might provide prognostic information.

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Human colorectal mucosal microbiota correlates with its host niche physiology revealed by endomicroscopy

Human colorectal mucosal microbiota correlates with its host niche physiology revealed by endomicroscopy | Digital Optical Biopsy | Scoop.it

The human gut microbiota plays a pivotal role in the maintenance of health, but how the microbiota interacts with the host at the colorectal mucosa is poorly understood.

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Assessment of Crohn's disease activity by confocal laser endomicroscopy - Neumann - 2012 - Inflammatory Bowel Diseases - Wiley Online Library

Assessment of Crohn's disease activity by confocal laser endomicroscopy - Neumann - 2012 - Inflammatory Bowel Diseases - Wiley Online Library | Digital Optical Biopsy | Scoop.it

Background:
Confocal laser endomicroscopy (CLE) allows microscopic imaging within the mucosal layer of the gut during ongoing endoscopy.

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GUEST OPINION: You'd be surprised who can get lung cancer - Glenwood Springs Post Independent

GUEST OPINION: You'd be surprised who can get lung cancer - Glenwood Springs Post Independent | Digital Optical Biopsy | Scoop.it
The public generally doesn’t think of lung cancer affecting people who are in their 20s or 30s — let alone someone who is seemingly fit and healthy and who
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BRIEF-Mauna Kea Technologies announces collaboration with Siemens ... - Reuters

Nov 3 (Reuters) - Mauna Kea Technologies SA :* Announces collaboration with Siemens Healthcare toevaluate endomicroscopy with Cellvizio in interventionalradiology* Doctors will use Cellvizio with Siemens...
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Endomicroscopy and electromyography of neuromuscular junctions in situ - Brown - 2014 - Annals of Clinical and Translational Neurology - Wiley Online Library

Published: Endomicroscopy and electromyography of neuromuscular junctions in situ #neurodegenerative #ccbs... http://t.co/PSwN9wQ1e0
Sacha Loiseau's insight:

Very interesting combination of an endomicroscopy probe and an electromyography probe ! 

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New laser helping patients with inflammatory bowel disease

New laser helping patients with inflammatory bowel disease | Digital Optical Biopsy | Scoop.it
Inflammatory bowel diseases, like Crohn's and ulcerative colitis, affect more than 1.5 million Americans.
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Medtronic’s CoreValve Aces Clinical Trial, Gets Speedy FDA Approval

Medtronic’s CoreValve Aces Clinical Trial, Gets Speedy FDA Approval | Digital Optical Biopsy | Scoop.it
Medtronic proudly announced that the FDA, thanks to outstanding study results, has bypassed asking an independent advisory panel for comment and approved the CoreValve transcatheter valve replacement system for patients with severe aortic stenosis...
Sacha Loiseau's insight:
This French phenomenal success is getting even better...
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EVA: Your Endomicroscopy Virtual Assistant for Cellvizio Optical Biopsy - YouTube

Mauna Kea Technologies introduces EVA, the Endomicroscopy Virtual Assistant that makes Cellvizio Optical Biopsy even more intuitive and integrated than ever ...
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Laser endomicroscope to be trialed in child heart surgery

Laser endomicroscope to be trialed in child heart surgery | Digital Optical Biopsy | Scoop.it
Cellvizio platform from Mauna Kea Technologies under evaluation in NIH-backed study.
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Laser endomicroscope to be trialed in child heart surgery

Laser endomicroscope to be trialed in child heart surgery | Digital Optical Biopsy | Scoop.it
Cellvizio platform from Mauna Kea Technologies under evaluation in NIH-backed study.
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Computer Aided Diagnosis for Confocal Laser Endomicroscopy in Advanced Colorectal Adenocarcinoma. - PubMed - NCBI

Computer Aided Diagnosis for Confocal Laser Endomicroscopy in Advanced Colorectal Adenocarcinoma. - PubMed - NCBI | Digital Optical Biopsy | Scoop.it
PLoS One. 2016 May 4;11(5):e0154863. doi: 10.1371/journal.pone.0154863. eCollection 2016.
Sacha Loiseau's insight:
CAD for CLE is clearly a very important avenue. Our own work on this matter is leading to exciting developments. This team is taking another approach which shows promises as well. 
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Mauna Kea Technologies Cellvizio Featured Prominently at 2016 World Congress for Bronchology and Interventional Pulmonology

Mauna Kea Technologies Cellvizio Featured Prominently at 2016 World Congress for Bronchology and Interventional Pulmonology | Digital Optical Biopsy | Scoop.it
From BioPortfolio: Mauna Kea Technologies (Euronext: MKEA, OTCQX: MKEAY) inventor of Cellvizio®, the multidisciplinary confocal lase
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Mauna Kea Technologies Completes Enrollment of 200 Patient Contact II Study on Characterization of Pancreatic Cysts with Needle-Based Confocal Laser Endomicroscopy

PARIS, February 25,2016 /PRNewswire/ -- Mauna Kea Technologies Completes Enrollment of 200 Patient Contact II Study on Characterization of Pancreatic Cysts...

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Development of a new classification for in vivo diagnosis of duodenal epithelial tumors with confocal laser endomicroscopy: A pilot study - Nonaka - 2015 - Digestive Endoscopy - Wiley Online Library

Development of a new classification for in vivo diagnosis of duodenal epithelial tumors with confocal laser endomicroscopy: A pilot study - Nonaka - 2015 - Digestive Endoscopy - Wiley Online Library | Digital Optical Biopsy | Scoop.it

Background and Aim
Confocal laser endomicroscopy (CLE) has been established for in vivo diagnosis of various gastrointestinal diseases. However, validated criteria for confocal diagnosis of duodenal tumors do not exist.

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Dr. Wellikoff talks about Cellvizio and Lung Cancer Awareness Month

Dr. Wellikoff talks about Cellvizio and Lung Cancer Awareness Month | Digital Optical Biopsy | Scoop.it
Dr. Adam Wellikoff at the Louisiana State University Health Sciences Center Shreveport is using Cellvizio to spot potential lung cancers.
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New molecular imaging technology could improve bladder-cancer detection, researchers say

New molecular imaging technology could improve bladder-cancer detection, researchers say | Digital Optical Biopsy | Scoop.it
Researchers have developed a new imaging method that targets a protein known as CD47 in human bladder cancer. This technology may greatly improve cancer detection and enable more accurate surgeries.
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NantHealth raised $320 million to bolst it's offers- a cloud-based, clinical decision support platform used by at least 250 hospitals

NantHealth raised $320 million to bolst  it's offers- a cloud-based, clinical decision support platform used by at least 250 hospitals | Digital Optical Biopsy | Scoop.it

NantHealth raised $320 million in a round led by Kuwait Investment Authority (KIA) with participation from Verizon, Celgene, BlackBerry, and Blackstone. KIA contributed $250 million to the round, according to Nant. This brings the company’s total funding to north of $400 million.

KIA also invested $100 million in NantHealth earlier this year — in May. BlackBerry’s investment in the company was announced in April.

NantHealth offers a cloud-based, clinical decision support platform used by at least 250 hospitals, according to the company. Nant offers a range of services, including a population health platform and a suite of products built to provide a learning system for the treatment of cancer.

In addition to the funding, NantHealth announced that former WebMD COO, United Healthcare CIO, and VantageMed CEO Steve Curd was hired as NantHealth’s Chief Operating Officer. The company also hired former Strand Diagnostics President and Genomics Health Vice President of US Sales Laura Beggrow as NantHealth’s executive vice president of commercialization.

“Our new leadership team has the expertise, relationships and deep knowledge necessary to drive NantHealth forward and make our vision of transforming the healthcare system and delivering truly personalized medicine a reality,” NantHealth CEO and Founder Patrick Soon-Shiong said in a statement. “Their addition to the company along with KIA’s continued investments show the strength and confidence in NantHealth’s ability to deliver on 21st century medicine and value-based population health care.”

NantHealth is something of a rollup since it includes a number of acquisitions over the years, like medication adherence offering Vitality GlowCaps and the home health technology provider Boston Life Labs. Nant Health also invested $8 million in Fluential, in November 2013, a stealthy but longstanding company working on “of speech optimization and deep language understanding tools for mobile devices, wearables and consumer ‘personal assistant’ applications.”


Via Chatu Jayadewa
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In Vivo Confocal Laser Endomicroscopy Improves Diagnosis of Barrett's ... - BioNews Texas

In Vivo Confocal Laser Endomicroscopy Improves Diagnosis of Barrett's ... - BioNews Texas | Digital Optical Biopsy | Scoop.it
In Vivo Confocal Laser Endomicroscopy Improves Diagnosis of Barrett's ...
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Surveillance of Barrett's esophagus: why biopsy if you can endomicroscopy

Gastrointestinal Endoscopy, Volume 79, Issue 2, Pages 222-223, February 2014, Authors:Manuel Berzosa, MD; Michael B.
Sacha Loiseau's insight:
Excellent editorial !
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Efficacy of confocal laser endomicroscopy for discriminating colorectal neoplasms from non-neoplasms: a systematic review and meta-analysis

Efficacy of confocal laser endomicroscopy for discriminating colorectal neoplasms from non-neoplasms: a systematic review and meta-analysis | Digital Optical Biopsy | Scoop.it
RT @TripCancer: Efficacy of confocal laser endomicroscopy for discriminating colorectal neoplasms from non-neoplasms http://t.co/hhOABBjOLj
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