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Study supports single-question alcohol screen for adolescents

Study supports single-question alcohol screen for adolescents | Not related | Scoop.it
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Wow. "For adolescents ages 18-20, the researchers found that the best screen for alcohol problems was to ask whether individuals had engaged in 12 or more drinking days (i.e., a day in which at least one standard drink is consumed) in the past year. Thirty-one percent of those who reported drinking at this level had alcohol use disorder"
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Solving the drink problem

The United Kingdom’s new guidelines on alcohol consumption are a sound example of evidence-based policymaking.
Yurii Aulchenko's insight:

Quote from the report: Drinking alcohol even at low levels contributes to a wide range of health harms, to a range of diseases and to hospital admissions. Hence, there is no level of drinking that can be recommended as completely safe long term ...

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The myopia boom

The myopia boom | Not related | Scoop.it
Short-sightedness is reaching epidemic proportions. Some scientists think they have found a reason why.
Yurii Aulchenko's insight:

Interesting. I knew that book-reading (even in poor light) did not increase risk of myopia, but did not know that current theory is that lack of exposure to bright light is the risk factor. 

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Rescooped by Yurii Aulchenko from ROBOTIC SURGERY
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Rise of Machines in Surgery Lowers Costs, Improves Patient Outcomes

Rise of Machines in Surgery Lowers Costs, Improves Patient Outcomes | Not related | Scoop.it
Robotic-assisted surgery is a game-changing technology in medicine, yet it is deeply misunderstood and often dismissed as just another expensive tool driving up the costs of surgery. This could not be farther from the truth....

Via Gilbert C FAURE
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Gilbert C FAURE's curator insight, June 10, 2014 5:43 AM

To date, more than 1.5 million da Vinci surgeries have been performed worldwide with an extremely low death rate, a declining rate of adverse events, and a growing body of clinical evidence that demonstrates safety, effectiveness and an ability to reduce both costs and complications of open surgery.

As a surgeon who has performed thousands of procedures -- including open manual laparoscopic and robotic-assisted urologic cancer surgeries -- author believes robotic-assisted surgery is the kind of technological disruption that truly will reform health care.

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Eat Breakfast to Lose Weight? Not So Fast

Eat Breakfast to Lose Weight? Not So Fast | Not related | Scoop.it
Study challenges conventional wisdom around morning meal
Yurii Aulchenko's insight:

Another conventional wisdom is wrong (or - the effect is small :) )

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$1,000 Pill For Hepatitis C Spurs Debate Over Drug Prices

$1,000 Pill For Hepatitis C Spurs Debate Over Drug Prices | Not related | Scoop.it
A drug to cure hepatitis C has FDA approval. But at $84,000 per person, who will have access to it?
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[1311.6876] Want a Good Answer? Ask a Good Question First!

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The authors study Stack Overflow and suggest a "family of algorithms to jointly predict the quality of questions and answers"

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Tweets loud and quiet - O'Reilly Radar

Tweets loud and quiet - O'Reilly Radar | Not related | Scoop.it
Writers who cover Twitter find the grandiose irresistible: nearly every article about the service’s IPO this fall mentioned the heroes of the Arab Spring who toppled dictators with 140-character...
Yurii Aulchenko's insight:

Quote: "Active Twitter accounts follow a median 117 users, and the vast majority of them–76%–follow more people than follow them. Which brings to mind both discussions about the mathematics of pairing and studies that suggest reciprocated friendship is both rare and valuable"

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Humor, laughter, and physical health: m - PubMed Mobile

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More rigorous and theoretically informed research is needed before firm conclusions can be drawn about possible health benefits of humor and laughter. Published in 2001, journal's impact factor 15
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Humor Theories and the Physiological Benefits of Laughter

Humor Theories and the Physiological Benefits of Laughter | Not related | Scoop.it
“ There are 3 main theories used to explain the functions of humor: (1) the relief theory, (2) the incongruity theory, and (3) the superiority theory.”
Yurii Aulchenko's insight:
Interesting read - need to track references - experimental designs are not clear, numbers were not that impressive - not sure, but I think official medicine does not consider laughter as a physiologically healing agent - impact factor of the publishing journal is 0.34 - who is up for few replication studies?!
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Earliest evidence for commensal processes of cat domestication

Earliest evidence for commensal processes of cat domestication | Not related | Scoop.it
Yurii Aulchenko's insight:

...earliest known (5,300 years ago) evidence for mutualistic relationships between people and cats... cats were advantageous to farmers [cats hunted mice eating grain], whereas food in villages was attractive to cats...


- telling noting about the fact that cats/kitties are cute, which might have been an important factor :)

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Men behaving nicely: Public goods as peacock tails - Van Vugt - 2012 - British Journal of Psychology - Wiley Online Library

Men behaving nicely: Public goods as peacock tails - Van Vugt - 2012 - British Journal of Psychology - Wiley Online Library | Not related | Scoop.it
Yurii Aulchenko's insight:

Men contributed more (to public fund) in the presence of an opposite sex audience... men's contributions went up as they rated the female observer more attractive... These findings support the idea that men compete with each other by creating public goods to impress women.

 

- Very logical idea, but p-values are not too impressive (0.04 and 0.05)

 

- Not sure the design of the experiment (game) is what I would have done - I would have probably set up an experiment with say street-begging or something

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Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia

Phase 3 Trial of Transplantation of Human Islets in Type 1 Diabetes Complicated by Severe Hypoglycemia | Not related | Scoop.it
OBJECTIVE Impaired awareness of hypoglycemia (IAH) and severe hypoglycemic events (SHEs) cause substantial morbidity and mortality in patients with type 1 diabetes (T1D). Current therapies are effective in preventing SHEs in 50–80% of patients with IAH and SHEs, leaving a substantial number of patients at risk. We evaluated the effectiveness and safety of a standardized human pancreatic islet product in subjects in whom IAH and SHEs persisted despite medical treatment.

RESEARCH DESIGN AND METHODS This multicenter, single-arm, phase 3 study of the investigational product purified human pancreatic islets (PHPI) was conducted at eight centers in North America. Forty-eight adults with T1D for >5 years, absent stimulated C-peptide, and documented IAH and SHEs despite expert care were enrolled. Each received immunosuppression and one or more transplants of PHPI, manufactured on site under good manufacturing practice conditions using a common batch record and standardized lot release criteria and test methods. The primary end point was the achievement of HbA1c <7.0% (53 mmol/mol) at day 365 and freedom from SHEs from day 28 to day 365 after the first transplant.

RESULTS The primary end point was successfully met by 87.5% of subjects at 1 year, and by 71% at 2 years. The median HbA1c level was 5.6% (38 mmol/mol) at both 1 and 2 years. Hypoglycemia awareness was restored, with highly significant improvements in Clarke and HYPO scores ( P > 0.0001). No study-related deaths or disabilities occurred. Five of the enrollees (10.4%) experienced bleeds requiring transfusions (corresponding to 5 of 75 procedures), and two enrollees (4.1%) had infections attributed to immunosuppression. Glomerular filtration rate decreased significantly on immunosuppression, and donor-specific antibodies developed in two patients.

CONCLUSIONS Transplanted PHPI provided glycemic control, restoration of hypoglycemia awareness, and protection from SHEs in subjects with intractable IAH and SHEs. Safety events occurred related to the infusion procedure and immunosuppression, including bleeding and decreased renal function. Islet transplantation should be considered for patients with T1D and IAH in whom other, less invasive current treatments would have been ineffective in preventing SHEs.
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Great to hear it is in such advanced stage
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Research Summer School in Statistical Omics, Split, Aug. 2015

Research Summer School in Statistical Omics, Split, Aug. 2015 | Not related | Scoop.it

The aim of this highly intensive School is training of a new generation of the Statistical Omics scientists who understand biology and technology behind the data and can apply modern methods to analysis of these data

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Two weeks left before application deadline for the Research Summer School in Statistical Omics

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A Steak in Genomics™: "Why Do Many Reasonable People Doubt Science?" Discussing the National Geographic Article

A Steak in Genomics™: "Why Do Many Reasonable People Doubt Science?" Discussing the National Geographic Article | Not related | Scoop.it
“Science is not a body of facts,” says geophysicist Marcia McNutt ... “Science is a method for deciding whether what we choose to believe has a basis in the laws of nature or not.”
Yurii Aulchenko's insight:

Quick interesting read

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NPR: When Women Stopped Coding

For decades, the share of women majoring in computer science was rising. Then, in the 1980s, something changed.

Via Mel Melendrez-Vallard
Yurii Aulchenko's insight:

Interesting stats and trends on %women in computer science, but I do not quite buy the explanation. Would be interesting to look how it went in different countries; also more areas of knowledge. 

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Want to Be a PI? What Are the Odds? | Science Careers

Want to Be a PI? What Are the Odds? | Science Careers | Not related | Scoop.it
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Predictive model for chances to become a PI :)

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The Snarky, Clever Comments Hidden in the "Acknowledgments" of Academic Papers

The Snarky, Clever Comments Hidden in the "Acknowledgments" of Academic Papers | Not related | Scoop.it
In a modern scientific paper, if you cruise past the “Materials and Methods” section and stop right before you hit the “References,” you’ll find the “Acknowledgments” section, wherein authors are given space to thank others for their contributions...
Yurii Aulchenko's insight:

Always thought I should hide something in this section which nobody reads. Apparently, not only me...

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Why a startup just published all of its employees’ salaries for the world to see

Why a startup just published all of its employees’ salaries for the world to see | Not related | Scoop.it
San Francisco-based social media startup Buffer just did something unprecedented: It published the salaries of every one of its employees online, available for the public to see.
Yurii Aulchenko's insight:

Quote: "Disclosing salaries within a company is one thing—it promotes openness and fairness, which is a good for morale—but disclosing every employee’s salary to the public is another thing entirely"

 

- Disclosing salaries within company would very much be in-line with the tradition of open book management

 

- Interesting to see their formulas for salary computations

 

- Salary is very little tied to profit. The questions is: if they have a bad year, then?..

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PLOS Biology: An Introduction to Social Media for Scientists

PLOS Biology: An Introduction to Social Media for Scientists | Not related | Scoop.it
“ PLOS Biology is an open-access, peer-reviewed journal that features works of exceptional significance in all areas of biological science, from molecules to ecosystems, including works at the interface with other disciplines.”
Via Mel Melendrez-Vallard
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Gilbert C FAURE's curator insight, July 8, 2014 3:28 AM

n the age of the internet, social media tools offer a powerful way for scientists to boost their professional profile and act as a public voice for science. Although the type of online conversations and shared content can vary widely, scientists are increasingly using social media as a way to share journal articles, advertise their thoughts and scientific opinions, post updates from conferences and meetings, and circulate information about professional opportunities and upcoming events. Google searches now represent the standard approach for discovering information about a topic or person—whether it be search committees collecting information about faculty candidates, graduate students searching out prospective labs, or journalists on the hunt for an expert source. Consequently, in today's technology-driven world, lack of an online presence can severely limit a researcher's visibility, and runs the risk that undesirable search results appear before desirable ones (however, this scenario is easily rectified; see Box 2). A growing body of evidence suggests that public visibility and constructive conversation on social media networks can be beneficial for scientists, impacting research in a number of key ways.

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14 Bad Habits That Prevent Inbox Zero

14 Bad Habits That Prevent Inbox Zero | Not related | Scoop.it
Check out these bad habits that can prevent Inbox Zero.
Yurii Aulchenko's insight:

Definitely agree that long emails, emotional emails is rather bad and is a major time killer. Rather make a phone call. Also agree that situation with emails is a bit of paradox: you are "done" when you have answered all, but your every email brings in reply emails. So do avoid writing emails unless really necessary :D

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From single-cell to cell-pool transcriptomes: stochasticity in gene expression and RNA splicing

From single-cell to cell-pool transcriptomes: stochasticity in gene expression and RNA splicing | Not related | Scoop.it
An international, peer-reviewed genome sciences journal featuring outstanding original research that offers novel insights into the biology of all organisms
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Emerging omics techniques

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Rescooped by Yurii Aulchenko from Future biomed
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Study linking GM maize to rat tumours is retracted

Study linking GM maize to rat tumours is retracted | Not related | Scoop.it
Publisher withdraws paper despite authors' objections, citing weak evidence.

Via Dmitry Alexeev
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