MERS-CoV
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PRO/AH/EDR> MERS-COV (03): Korea, virus mutation

PRO/AH/EDR> MERS-COV (03): Korea, virus mutation | MERS-CoV | Scoop.it

PRO/AH/EDR> MERS-COV (03): Korea, virus mutation https://t.co/CYxwtjhuhN #HazMat

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Oman - MoH announces new coronavirus MERS case - January 4, 2016 - FluTrackers

Oman announces seventh confirmed case of infection Coruna The Ministry of Health announced today (Monday) for the diagnosis of new cases of AIDS Middle East acute
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Avian Flu Diary: WHO MERS Update - Oman

Avian Flu Diary: WHO MERS Update - Oman | MERS-CoV | Scoop.it

#10,864Earlier this week in Oman: MOH Announces 7th MERS Case, we learned of a new Coronavirus infection, but few details were provided.

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Study by Chinese Researchers Reveals Different Variants of MERS Virus

Study by Chinese Researchers Reveals Different Variants of MERS Virus | MERS-CoV | Scoop.it

A study led by Chinese researchers published on Friday, Dec.

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MERS virus: Drying out the reservoir

MERS virus: Drying out the reservoir | MERS-CoV | Scoop.it

The recently discovered coronavirus now referred to as MERS (for Middle East Respiratory Syndrome) causes an infectious respiratory disease in humans, which can be fatal. The virus is thought to be transmitted to humans primarily via contact with dromedary camels. Now researchers led by virologist Gerd Sutter at Ludwig-Maximilians-Universität (LMU) in Munich, in collaboration with teams led by Professor Bart L. Haagmans of the Erasmus Medical Center (MC) in Rotterdam and Professor Albert Osterhaus of University of Veterinary Medicine Hannover, Foundation (TiHo), have successfully tested a candidate vaccine against MERS, in camels. "We have been able to show, for the first time, that our vaccine can significantly reduce the virus load in infected camels," says Sutter. The results of the trial appear in the latest issue of the journal "Science".

The new vaccine, MVA-MERS-S, was developed by Sutter and his team two years ago. In cooperation with researchers based at Philipps University in Marburg and the team in Rotterdam, he introduced a gene for the so-called spike protein of MERS into the genome of a weakened strain of poxvirus (MVA). The resulting modified poxvirus particles expressed the MERS protein on the surface of infected cells, and these engineered viruses form the basis of the new vaccine. Several preliminary data over the past two years have confirmed the immunogenicity and efficacy of MVA-MERS-S in mice. The scientists now describe the outcome of the first direct test of the vaccine in camels.

 

The MERS virus was first identified in Saudi Arabia in 2012. To date, some 1400 cases of MERS have been reported, of which one-third proved fatal. Its primary hosts, however, are dromedary camels, as revealed by the detection of antiviral antibodies and the presence of MERS particles in the nasal cavity in infected animals. Although camels infected with the virus show relatively mild symptoms, all the evidence suggests that they can transmit the pathogen to humans, who can subsequently pass it on to others. Hence, vaccination of camels against MERS virus is an obvious method of choice for the prevention of human infections. Successful immunization would deprive the virus of its primary host and break the chain of transmission, effectively minimizing the risk of future MERS epidemics in human populations.

But the vaccine from Sutter's laboratory actually turns out to another advantage: "Immunization with MVA-MERS-S simultaneously protects camels from camelpox, a disease similar to smallpox in humans - which can be life-threatening in dromedaries," Bart L. Haagmans of the Erasmus Medical Center explains.


In camels infected with the MERS virus, symptoms of disease are confined to the upper respiratory tract. In the new study, the researchers infected a total of 8 camels. Half of these had been immunized, both intranasally and intramuscularly, with MVA-MERS-S three weeks prior to exposure to the virus. "In this group of animals, the vaccine had induced the development of sufficient amounts of antibodies to inhibit viral multiplication and prevent the appearance of disease symptoms upon infection," says Dr. Asisa Volz, a member of Prof. Sutter's group. In addition, anti-MERS antibodies were detected in both the nasal mucosa and in the bloodstream of immunized animals. The controls, on the other hand, which were injected with poxviruses particles lacking the S protein, exhibited the typical runny nose, and infectious virus was readily detectable in nasal secretions. "Our results clearly show that vaccination with MVA-MERS-S markedly reduces the numbers of viruses present in the nasal epithelia of camels," says Albert Osterhaus of the Universität der Veterinärmedizin, Hannover.


Via Dr. Stefan Gruenwald
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Hospital patient with suspected MERS virus is held in isolation at Manchester Royal Infirmary

Hospital patient with suspected MERS virus is held in isolation at Manchester Royal Infirmary | MERS-CoV | Scoop.it
The patient was admitted to the hospital’s Accident and Emergency department with a respiratory infection and has been placed in isolation as a precaution
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Saudi Arabia - 1 new Coronavirus MERS case, November 29, 2015 - FluTrackers

Saudi Arabia - 1 new Coronavirus MERS case, November 29, 2015 - FluTrackers | MERS-CoV | Scoop.it
MOH: '1 New Confirmed Corona Cases Recorded' (http://www.moh.gov.sa/en/CCC/PressReleases/Pages/statistics-2015-11-29-001.aspx) MOH: '1 New Confirmed Corona Cases
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Scientists Just Created A Dangerous New Form Of SARS

Scientists Just Created A Dangerous New Form Of SARS | MERS-CoV | Scoop.it
‘It’s been well over a decade since the SARS virus captured the attention of the world, and very nearly devastated the global population.
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Saudi Arabia: Another MERS case in Riyadh, 1/3 of country total health care ... - Outbreak News Today

Saudi Arabia: Another MERS case in Riyadh, 1/3 of country total health care ... - Outbreak News Today | MERS-CoV | Scoop.it
Outbreak News Today
Saudi Arabia: Another MERS case in Riyadh, 1/3 of country total health care ...
Outbreak News Today
After a lull in new cases of Middle East respiratory syndrome coronavirus (MERS-CoV) in Saudi Arabia (no new cases since Oct.
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Middle East respiratory syndrome coronavirus (MERS-CoV) – Saudi Arabia - World Health Organization

Middle East respiratory syndrome coronavirus (MERS-CoV) – Saudi Arabia World Health Organization Between 17 and 24 October 2015, the National IHR Focal Point for the Kingdom of Saudi Arabia notified WHO of 12 additional cases of Middle East...
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Middle East respiratory syndrome coronavirus (MERS-CoV) – Republic of Korea - World Health Organization

On 12 October 2015, the National IHR Focal Point of the Republic of Korea provided follow-up information on a previously reported case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection.
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Two positive cases of MERS Coronavirus announced in Abu Dhabi - Dubai Chronicle

Two positive cases of MERS Coronavirus announced in Abu Dhabi - Dubai Chronicle | MERS-CoV | Scoop.it

Modify your meta The Health Authority - Abu Dhabi, HAAD, has announced two positive cases of the MERS Coronavirus (MERS CoV) by editing it right here

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Middle East respiratory syndrome coronavirus (MERS-CoV) – Oman

On 3 January 2016, the National IHR Focal Point of Oman notified WHO of 1 additional case of Middle East respiratory syndrome coronavirus (MERS-CoV) infection.

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Mutation detected in S. Korean MERS virus: government

Mutation detected in S. Korean MERS virus: government | MERS-CoV | Scoop.it
The Middle East Respiratory Syndrome (MERS) virus that spread through South Korea last year underwent a mutation that could have affected its ability to infect people and the fatality rate, the government said Friday.The Korea Centers for Disease...
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Camels, Cattle and Coronavirus: the Hunt Must Continue

Camels, Cattle and Coronavirus: the Hunt Must Continue | MERS-CoV | Scoop.it
Significant zoonotic sources and routes of transmission of MERS-CoV may yet be identified. This article briefly reviews the animals that potentially harbour MERS-CoV.
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Saudi dies of MERS in Hofuf

Saudi dies of MERS in Hofuf | MERS-CoV | Scoop.it

RIYADH: The Middle East Respiratory Syndrome coronavirus (MERS-CoV) claimed the life of a 57-year-old Saudi man on Sunday, according to an official from the Ministry of Health.

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Saudi Arabia - 1 new Coronavirus MERS case, December 1, 2015 - FluTrackers

Saudi Arabia - 1 new Coronavirus MERS case, December 1, 2015 - FluTrackers | MERS-CoV | Scoop.it
MOH: '1 New Confirmed Corona Cases Recorded' (http://www.moh.gov.sa/en/CCC/PressReleases/Pages/statistics-2015-12-01-001.aspx) http://www.moh.gov.sa/en/CCC/PressReleases/PublishingImages/1-12-2015-01.jpg...
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UK - Manchester patient tested for coronavirus MERS - FluTrackers

UK - Manchester patient tested for coronavirus MERS
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S.Korea - No Mutations Found In Coronavirus-MERS Outbreak, 2015 - FluTrackers

Volume 22, Number 2—February 2016 Dispatch Microevolution of Outbreak-Associated Middle East Respiratory Syndrome Coronavirus, South Korea, 2015 Abstract
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Global experts to address coronavirus conference - Saudi Gazette

Global experts to address coronavirus conference - Saudi Gazette | MERS-CoV | Scoop.it
King Abdulaziz City for Science and Technology will host an international conference on vaccines for the Middle East Respiratory Syndrome (coronavirus)
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MoH plans tougher rules to check coronavirus - Arab News

MoH plans tougher rules to check coronavirus - Arab News | MERS-CoV | Scoop.it
JEDDAH: The Ministry of Health is studying the possibility of enacting tougher norms to protect patients from contracting infections at health facilities, especially the MERS coronavirus, an official
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