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MERS-Coronavirus The Next Global Pandemic - Death Toll 58 And Climbing

MERS-Coronavirus The Next Global Pandemic - Death Toll 58 And Climbing | MERS-CoV | Scoop.it
  Reuters News Service just announced two more new cases and another death from the deadly MERS virus. Could MERS be the next global pandemic? The 3 new cases were headline news in the Arab online ...
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Experts express concern over coronavirus infection - Arab News

Experts express concern over coronavirus infection - Arab News | MERS-CoV | Scoop.it
UW Today
Experts express concern over coronavirus infection
Arab News
Health experts have expressed their concern at the increasing number of coronavirus infection reports and resulting deaths in different parts of the country.
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Scientists engineer strain of MERS coronavirus for use in a vaccine

Scientists have developed a strain of the Middle East respiratory syndrome coronavirus that could be used as a vaccine against the disease, according to a study to be published in mBio®, the online open-access journal of the American Society for...
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MERS-CoV, Saudi Arabia: MoH announces four new human cases (September 10 2013): 100 cases, 47 deaths so far - FluTrackers

MERS-CoV, Saudi Arabia: MoH announces four new human cases (September 10 2013): 100 cases, 47 deaths so far - FluTrackers | MERS-CoV | Scoop.it
MERS-CoV, Saudi Arabia: MoH announces four new human cases (September 10 2013): 100 cases, 47 deaths so far Novel Coronavirus - NCoV ( hCoV-EMC) 2012 - 2013 (RT @FluTrackers: #Saudi Arabia - MoH announces 4 new #nCoV #coronavirus human cases (September...
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Toronto SARS expert to go to Saudi Arabia to help with coronavirus ...

Toronto SARS expert to go to Saudi Arabia to help with coronavirus ... | MERS-CoV | Scoop.it
Authorities in Saudi Arabia have invited outside experts to help it deal with a large outbreak of the new coronavirus in the eastern Saudi city of al Hofuf, and a Canadian infectious diseases specialist is among them.
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3 more Saudis die of SARS-like virus

3 more Saudis die of SARS-like virus | MERS-CoV | Scoop.it
Three more die of MERS coronavirus in Saudi Arabia, the health ministry says.
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The Many Mysteries of MERS | The Scientist Magazine®

The Many Mysteries of MERS | The Scientist Magazine® | MERS-CoV | Scoop.it
As researchers test a treatment for Middle East respiratory syndrome, the deadly coronavirus that causes it slowly reveals itself.
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As MERS-coronavirus death toll rises, more evidence points to dromedary camels as source

As MERS-coronavirus death toll rises, more evidence points to dromedary camels as source | MERS-CoV | Scoop.it
Two Saudi women have died from the MERS coronavirus, raising to 44 the number of people in the kingdom who have died from the SARS-like virus.
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WHO | World Health Organization Updates 6-7 September 2013

WHO | World Health Organization        Updates 6-7 September 2013 | MERS-CoV | Scoop.it
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Saudi Arabia reports 2 more deaths from SARS-like virus - CTV News

Saudi Arabia reports 2 more deaths from SARS-like virus - CTV News | MERS-CoV | Scoop.it
CTV News Saudi Arabia reports 2 more deaths from SARS-like virus CTV News RIYADH, Saudi Arabia - Saudi Arabia's Health Ministry says two more people have died from an SARS-like virus, raising the total number of fatalities in the centre of the...
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Pandemic Information News: #MERS #Coronavirus Saudi Arabia MOH Announces New Registration of 2 Deaths & 2 Cases

Pandemic Information News: #MERS #Coronavirus Saudi Arabia MOH Announces New Registration of 2 Deaths & 2 Cases | MERS-CoV | Scoop.it
RT @pandemic_news: #MERS #Coronavirus Saudi Arabia MOH Announces New Registration of 2 Deaths & 2 Cases http://t.co/ooW6pZ6Znp
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Emergence of the Middle East Respiratory Syndrome Coronavirus

Emergence of the Middle East Respiratory Syndrome Coronavirus | MERS-CoV | Scoop.it

It began routinely enough. A patient with severe respiratory disease at the Dr. Soliman Fakeeh Hospital in Jeddah, Saudi Arabia was getting worse and no one knew why. A sample of sputum was sent to Dr. Ali Mohamed Zaki to identify the culprit, as he had identified these diseases many times before. However, this time would be different. The sample showed no positive hits on any of the virus assays he normally used. He contacted Dr. Ron Fouchier, at Erasmus Medical College in Rotterdam, Netherlands, to see if he could be of help. Dr. Zaki's initial idea was that the virus was a paramyxovirus, and Dr Fouchier had recently published a Pan-paramyxovirus polymerase chain reaction (PCR) assay [1]. In Dr. Fouchier's lab, the virus was identified as a novel coronavirus, one that had never been seen before.

 

Coronavirus graphic from Russell Kightley Media

 

 


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Ed Rybicki's curator insight, September 5, 2013 11:39 PM

Nice account of how MERS emerged - and what may happen with it.

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Qatar reports first coronavirus death - Kuwait News Agency

Qatar reports first coronavirus death - Kuwait News Agency | MERS-CoV | Scoop.it
Al-Shorfa Qatar reports first coronavirus death Kuwait News Agency DOHA, Sept 3 (KUNA) -- Qatar's Supreme Council of Health (SCH) reported Tuesday the first confirmed death of the Middle East Respiratory Syndrome coronavirus and the third case...
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Mers - will it start the next global pandemic? - The Guardian

Mers - will it start the next global pandemic? - The Guardian | MERS-CoV | Scoop.it
The Guardian
Mers - will it start the next global pandemic?
The Guardian
Since April 2012, 108 cases of a new virus have been reported in humans, resulting in 50 deaths.
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MERS continues grip in Saudi Arabia - Xinhua | English.news.cn

MERS continues grip in Saudi Arabia - Xinhua | English.news.cn | MERS-CoV | Scoop.it
After killing one more in Saudi Arabia, the MERS virus continues its grip.
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Eight new Saudi cases push global MERS total to 130 - CIDRAP

Eight new Saudi cases push global MERS total to 130 - CIDRAP | MERS-CoV | Scoop.it
CIDRAP Eight new Saudi cases push global MERS total to 130 CIDRAP Marc Sprenger, MD, PhD, director of the European Centre for Disease Prevention and Control (ECDC) told CIDRAP News that his agency continues to collect and analyze data about new...
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Engineering a Replication-Competent, Propagation-Defective Middle East Respiratory Syndrome Coronavirus as a Vaccine Candidate

ABSTRACT

Middle East respiratory syndrome coronavirus (MERS-CoV) is an emerging coronavirus infecting humans that is associated with acute pneumonia, occasional renal failure, and a high mortality rate and is considered a threat to public health. The construction of a full-length infectious cDNA clone of the MERS-CoV genome in a bacterial artificial chromosome is reported here, providing a reverse genetics system to study the molecular biology of the virus and to develop attenuated viruses as vaccine candidates. Following transfection with the cDNA clone, infectious virus was rescued in both Vero A66 and Huh-7 cells. Recombinant MERS-CoVs (rMERS-CoVs) lacking the accessory genes 3, 4a, 4b, and 5 were successfully rescued from cDNA clones with these genes deleted. The mutant viruses presented growth kinetics similar to those of the wild-type virus, indicating that accessory genes were not essential for MERS-CoV replication in cell cultures. In contrast, an engineered mutant virus lacking the structural E protein (rMERS-CoV-ΔE) was not successfully rescued, since viral infectivity was lost at early passages. Interestingly, the rMERS-CoV-ΔE genome replicated after cDNA clone was transfected into cells. The infectious virus was rescued and propagated in cells expressing the E protein in trans, indicating that this virus was replication competent and propagation defective. Therefore, the rMERS-CoV-ΔE mutant virus is potentially a safe and promising vaccine candidate to prevent MERS-CoV infection.


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Camel MERS Antibodies Raise Surveillance Concerns

Recombinomics Commentary (Carmel #MERS antibodies raise serious surveillance concerns #beta2c #nCoV #coronavirus #SARS-like http://t.co/NfBo64fmNl)
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Treatment For Middle East Coronavirus Works In Monkey Tests : NPR

Treatment For Middle East Coronavirus Works In Monkey Tests : NPR | MERS-CoV | Scoop.it
Scientists offer a glimmer of hope that a treatment for humans with the deadly disease might be on the horizon.
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MERS-coronavirus kills one person in Saudi Arabia, another in Qatar - Reuters

MERS-coronavirus kills one person in Saudi Arabia, another in Qatar Reuters DUBAI, Sept 8 (Reuters) - The MERS coronavirus has killed two more people in the Gulf, one in Saudi Arabia where the strain emerged last year, and one in neighbouring...
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Pandemic Information News: #MERS Turkey Suspected Case Died and 3 Others Transferred to Riyadh KSA

Pandemic Information News: #MERS Turkey Suspected Case Died and 3 Others Transferred to Riyadh KSA | MERS-CoV | Scoop.it
#MERS Turkey Suspected Case Died and 3 Others Transferred to Riyadh KSA http://t.co/usiNam00C1
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MERS-CoV, Saudi Arabia: 4 new confirmed cases, including 2 new deaths (MoH, September 7 2013): 92 cases, 46 deaths so far (real number of cases announced by Saudi MoH is 96) - FluTrackers

MERS-CoV, Saudi Arabia: 4 new confirmed cases, including 2 new deaths (MoH, September 7 2013): 92 cases, 46 deaths so far (real number of cases announced by Saudi MoH is 96) - FluTrackers | MERS-CoV | Scoop.it
MERS-CoV, Saudi Arabia: 4 new confirmed cases, including 2 new deaths (MoH, September 7 2013): 92 cases, 46 deaths so far (real number of cases announced by Saudi MoH is 96) Novel Coronavirus - NCoV ( hCoV-EMC) 2012 - 2013 (#nCoV, #Saudi Arabia: 2...
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Turkey: A little more on the suspected MERS cases

BIRD FLU NEWS Turkey: A little more on the suspected MERS cases (crofsblogs) http://t.co/dS74hOTQLH follow warren today
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MERS-CoV, Saudi Arabia: Ministry of Health Update (September 5 2013): 88 cases, 44 deaths so far - FluTrackers

MERS-CoV, Saudi Arabia: Ministry of Health Update (September 5 2013): 88 cases, 44 deaths so far - FluTrackers | MERS-CoV | Scoop.it
MERS-CoV, Saudi Arabia: Ministry of Health Update (September 5 2013): 88 cases, 44 deaths so far Novel Coronavirus - NCoV ( hCoV-EMC) 2012 - 2013 (RT@FluTrackers #Saudi Arabia - MoH announces 4 more #nCoV #coronavirus cases including 2 deaths
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Qatar announces first fatality from Sars-like Mers virus - Straits Times

Qatar announces first fatality from Sars-like Mers virus - Straits Times | MERS-CoV | Scoop.it
Qatar announces first fatality from Sars-like Mers virus Straits Times DOHA (AFP) - A woman has died in Qatar after contracting the Mers coronavirus, becoming the first recorded fatality from the Sars-like virus in the Gulf state, local press...
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