Current status of chemokines in the adult CNS | Neuroscience_topics | Scoop.it

Highlights

  • A better understanding of the role of chemokines and their receptors in the CNS in addition to the immune system.
  • This review focuses on recent data about three couples CXCL12/CXCR4, CCL2/CCR2, and CX3CL1/CX3CR1 in the adult CNS.
  • Description of their cellular expression, distributions, and roles in neurotransmission and neuromodulation.
  • This review summarizes current evidence on the role of these chemokine systems in the pathogenesis of CNS disorders.

by Réaux-Le Goazigo A. et al.Progress in Neurobiology, In Press, Available online 27 February 2013