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Neuroscience_technics
Neuroscience requires a wide range of technologies
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The OpenPicoAmp : an open-source planar lipid bilayer amplifier for hands-on learning of neuroscience

The OpenPicoAmp : an open-source planar lipid bilayer amplifier for hands-on learning of neuroscience | Neuroscience_technics | Scoop.it

Neuroscience education can be promoted by the availability of low cost and engaging teaching materials. To address this issue, we developed an open-source lipid bilayer amplifier, the OpenPicoAmp, which is appropriate for use in introductory courses in biophysics or neurosciences dealing with the electrical properties of the cell membrane. The amplifier is designed using the common lithographic printed circuit board fabrication process and off-the-shelf electronic components. In addition, we propose a specific design for experimental chambers allowing the insertion of a commercially available polytetrafluoroethylene film. This experimental setup can be used in simple experiments in which students monitor the bilayer formation by capacitance measurement and record unitary currents produced by ionic channels like gramicidin A. Used in combination with a low-cost data acquisition board this system provides a complete solution for hands-on lessons, therefore improving the effectiveness in teaching basic neurosciences or biophysics. - by Shlyonsky V et al., arXiv:1403.7439 2014 

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Journal Club: Tracking a complete voltage-sensor cycle with metal-ion bridges

Journal Club: Tracking a complete voltage-sensor cycle with metal-ion bridges | Neuroscience_technics | Scoop.it

In this post I would like to start an online discussion about a very interesting recent PNAS paper: Tracking a complete voltage-sensor cycle with metal-ion bridges by Henrion et al. I know that other people in the voltage-gated cation channel field are very interested in this paper and it also relates to many of the topics I have been discussing in my posts. I thought it would be a good idea to discuss it and a journal club type format encourages contributions from anyone who is interested. So read the paper and join in the discussion! (...) - by M Letts on LettsScience, August 26, 2012

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