Neurogenic Orthostatic Hypotension
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Stand Studies is Currently Enrolling Patients

Stand Studies is Currently Enrolling Patients | Neurogenic Orthostatic Hypotension | Scoop.it
"If you are at least 18 years old and have symptomatic orthostatic hypotension (SOH), you may be eligible to participate in a STAND 405/406 clinical research study.
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MSA Coalition's comment, June 21, 2013 10:34 AM
Did you know if midodrine is not found to be effective in these studies, the FDA may withdrawal it from the US market? If this happens and the FDA does not approve droxidopa soon, patients suffering and disabled by neurogenic orthostatic hypotension will have no FDA approved treatment options.
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Association between orthostatic hypotension and cardiovascular risk, cerebrovascular risk, cognitive decline and falls as well as overall mortality: a systematic review and meta-analysis

Association between orthostatic hypotension and cardiovascular risk, cerebrovascular risk, cognitive decline and falls as well as overall mortality: a systematic review and meta-analysis | Neurogenic Orthostatic Hypotension | Scoop.it
Neurology Medical Article: Association between orthostatic hypotension and cardiovascular risk, cerebrovascular risk, cognitive decline and falls as well as overall mortality: a systematic review and meta-analysis (Association between orthostatic...
MSA Coalition's insight:

An interesting meta-analysis on the risks of orthostatic hypotension

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Droxidopa for neurogenic orthostatic hypotension: A randomized, placebo-controlled, phase 3 trial

Droxidopa for neurogenic orthostatic hypotension: A randomized, placebo-controlled, phase 3 trial | Neurogenic Orthostatic Hypotension | Scoop.it
Neurology Medical Article: Droxidopa for neurogenic orthostatic hypotension: A randomized, placebo-controlled, phase 3 trial (#neurology Droxidopa for neurogenic orthostatic hypotension: A randomized, placebo-controlled, phase 3 trial: ...
MSA Coalition's insight:

We are still awaiting news on when droxidopa will become available in the US for those suffering from neurogenic orthostatic hypotension (neurogenic OH).  Droxidopa was approved by the FDA earlier this year.  We will keep you updated as we hear more.

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Understanding the FDA Committee’s Decision to Recommend Approval for Neurogenic Orthostatic Hypotension Drug

Understanding the FDA Committee’s Decision to Recommend Approval for Neurogenic Orthostatic Hypotension Drug | Neurogenic Orthostatic Hypotension | Scoop.it
From James Beck, Ph.D., Director of Research ProgramsYou may have read the recent news about the small pharmaceutical company,Chelsea Therapeutics, and their drug Northera™ (droxidopa). Chelsea rec...
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US advisory panel backs approval for Chelsea drug Northera - Reuters

US advisory panel backs approval for Chelsea drug Northera - Reuters | Neurogenic Orthostatic Hypotension | Scoop.it
US advisory panel backs approval for Chelsea drug Northera Reuters It is designed to treat neurogenic orthostatic hypotension (NOH), a rare, chronic type of low blood pressure that occurs on standing and is associated with certain neurological...
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Chelsea Therapeutics Announces First Patient Dosed in ...

Chelsea Therapeutics Announces First Patient Dosed in ... | Neurogenic Orthostatic Hypotension | Scoop.it
Symptomatic nOH is a chronic disorder that is caused by an underlying neurogenic disorder, such as Parkinson's disease, multiple system atrophy (MSA) or pure autonomic failure (PAF). Symptoms of nOH include dizziness, ...
MSA Coalition's insight:

Chelsea THerapeutics has started enrollment for their latest neurogenic orthostatic hypotension clinical trial

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Letters about Neurogenic Orthostatic Hypotension Needed

Letters about Neurogenic Orthostatic Hypotension Needed | Neurogenic Orthostatic Hypotension | Scoop.it
If you have neurogenic orthostatic hypotension and live in the US your help is needed. Write to the FDA and Congress so they know the unmet need.
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FDA Panel to Review Chelsea's Northera - Yahoo News

FDA Panel to Review Chelsea's Northera - Yahoo News | Neurogenic Orthostatic Hypotension | Scoop.it
FDA Panel to Review Chelsea's Northera Yahoo News Chelsea Therapeutics is looking to get Northera approved for the treatment of symptomatic neurogenic orthostatic hypotension (:NOH) in patients with primary autonomic failure (Parkinson's disease,...
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What is Orthostatic Hypotension: The Dizzy Standup

What is Orthostatic Hypotension: The Dizzy Standup | Neurogenic Orthostatic Hypotension | Scoop.it
With my family’s history of heart disease I tend to over analyze and worry about everything that may have to do with my heart (probably not good for my stress levels!) One example of this is when o...
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Chelsea Therapeutics Says FDA Panel to Review Northera ...

Chelsea Therapeutics Says FDA Panel to Review Northera ... | Neurogenic Orthostatic Hypotension | Scoop.it
NOH is a chronic neurogenic disorder resulting from deficient release of norepinephrine that predominantly affects patients with primary autonomic failure, a group of diseases which includes Parkinson's disease (PD), multiple ...
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Chelsea Therapeutics Announces FDA Advisory Committee to Review ... - Virtual-Strategy Magazine (press release)

Chelsea Therapeutics Announces FDA Advisory Committee to Review ...
MSA Coalition's insight:

January 14th will be an important day for the future of neurogenic orthostatic hypotension treatments

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Why New neurogenic Orthostatic Hypotension Treatments Are Needed

Why New neurogenic Orthostatic Hypotension Treatments Are Needed | Neurogenic Orthostatic Hypotension | Scoop.it
RT @TreatNOH: Why New neurogenic Orthostatic Hypotension Treatments Are Needed http://t.co/oicMJvGRF5 via @sharethis
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Orthostatic Hypotension in Patients with Dementia: Clinical... : Cognitive and Behavioral Neurology

Orthostatic Hypotension in Patients with Dementia:  Clinical... : Cognitive and Behavioral Neurology | Neurogenic Orthostatic Hypotension | Scoop.it
Objective:To evaluate orthostatic hypotension (OH) prevalence, risk factors, signs and symptoms, and treatment response in patients with dementia.
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Does Advocacy Make A Difference « MSA

Does Advocacy Make A Difference « MSA | Neurogenic Orthostatic Hypotension | Scoop.it
Just last month, The MSA Coalition®, a few other advocacy group leaders, two caring physicians, and about a dozen patients suffering from neurogenic orthostatic hypotension (neurogenic OH) made a big impact on an ...
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Mayo Edge: Dizziness a common problem with many possible causes - Post-Bulletin

Mayo Edge: Dizziness a common problem with many possible causes - Post-Bulletin | Neurogenic Orthostatic Hypotension | Scoop.it
Mayo Edge: Dizziness a common problem with many possible causes
Post-Bulletin
This can be triggered by a common condition known as orthostatic hypotension or postural hypotension.
MSA Coalition's insight:

Orthostatic hypotension (OH) is also very common in multiple system atrophy patients.  In fact, as many as 80% of all MSA patients suffer from symptomatic neurogenic OH.

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FDA approves droxidopa for neurogenic orthostatic hypotension ...

FDA approves droxidopa for neurogenic orthostatic hypotension ... | Neurogenic Orthostatic Hypotension | Scoop.it
... has been approved for the treatment of patients with neurogenic orthostatic hypotension, a rare, chronic, and often debilitating condition associated with Parkinson's disease, multiple system atrophy, and pure autonomic failure, the Food ...
MSA Coalition's insight:

Droxidopa has been approved by the FDA for neurogenic orthostatic hypotension (low blood pressure upon standing that is caused by a neurological condition.)

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Search of: midodrine | Active, not recruiting | orthostatic hypotension | Phase 4 - List Results - ClinicalTrials.gov

panelist commentary, labeling, as well as midodrine pIV studies set to report out Q2/mid yr may keep lid on $CHTP http://t.co/L6fe0ZAbcl
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Chelsea Therapeutics' Northera Gets Strong Support From FDA Panel - Wall Street Journal

Chelsea Therapeutics' Northera Gets Strong Support From FDA Panel - Wall Street Journal | Neurogenic Orthostatic Hypotension | Scoop.it
Chelsea Therapeutics' Northera Gets Strong Support From FDA Panel Wall Street Journal The firm said its impression was that "the panel came to appreciate the vagaries of clinical trials for neurological disorders especially in orphan diseases like...
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Neurally Mediated Syncope (NMS) in Nursing Care | DeltaBiology.com

Neurally Mediated Syncope (NMS) in Nursing Care | DeltaBiology.com | Neurogenic Orthostatic Hypotension | Scoop.it
Chronic Primary. Pure autonomic failure; Multiple system atrophy. Chronic Secondary. Diabetes; Amyloid; Paraneoplastic syndromes; Drugs. Neurally Mediated (Reflex). Carotid sinus hypersensitivity; Glossopharyngeal ...
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Sign Up For Neurogenic Orthostatic Hypotension Clinical Trial Opportunities

Sign Up For Neurogenic Orthostatic Hypotension Clinical Trial Opportunities | Neurogenic Orthostatic Hypotension | Scoop.it
Do you have symptomatic neurogenic orthostatic hypotension? If yes, are you interested in being made aware of new clinical trial opportunities?
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Efficacy of treatments for orthostatic hypotension: a systematic review

Efficacy of treatments for orthostatic hypotension: a systematic review | Neurogenic Orthostatic Hypotension | Scoop.it
Via @GerisReg: Limited evidence for treatment of orthostatic hypotension

http://t.co/MkwsUJpKDZ”; #Falls #ptsafety #PreventingFalls
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Orthostatic Hypotension - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References - Icon Health Publications - Download Educational

Orthostatic Hypotension - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References - Icon Health Publications - Download Educational | Neurogenic Orthostatic Hypotension | Scoop.it
This is a 3-in-1 reference book. It gives a complete medical dictionary covering hundreds of DOWNLOAD (Orthostatic Hypotension - A Medical Dictionary, Bibliography, and Annotated Research Guide to Internet References...
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Low Blood Pressure is What Causes Fainting - Telemanagement

Low Blood Pressure is What Causes Fainting - Telemanagement | Neurogenic Orthostatic Hypotension | Scoop.it
Telemanagement Low Blood Pressure is What Causes Fainting Telemanagement Postural hypotension may be due to a large number of causes, including damage to the autonomic nervous system by diabetes (diabetic autonomic neuropathy), a rare, progressive...
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2013 - Multiple System Atrophy

2013 - Multiple System Atrophy | Neurogenic Orthostatic Hypotension | Scoop.it
Gregor K. Wenning, "Multiple System Atrophy"


English | ISBN: 3709106869 | 2013 | 198 pages | PDF | 5 MB


This textbook provides a comprehensive monography on multiple system ...
MSA Coalition's insight:

A new book exclusibely on Multiple System Atrophy. Thank you Professor Wenning for your dedication to the MSA community!!

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Systolic and diastolic component of orthostatic hypotension... : Journal of Hypertension

Objective: Impact of SBP vs. DBP decrement during orthostasis on cardiovascular events in hypertension is not clear.
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More than mere coincidence leads TGen to explore rare disease (Video) - Phoenix Business Journal

More than mere coincidence leads TGen to explore rare disease (Video) - Phoenix Business Journal | Neurogenic Orthostatic Hypotension | Scoop.it
Call it what you want — whether it’s God answering prayers or the stars aligning... VIDEO
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